SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5y6g FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		4 / 5 LEU A 146
PRO A 122
ALA A 121
ILE A 119
 None
 0.83A 2aofB-5y6gA:
undetectable		 2aofB-5y6gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 5y6g FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		5 / 11 LEU A 209
LEU A 139
MET A 176
VAL A 174
ILE A 172
 None
 1.04A 2uxoB-5y6gA:
undetectable		 2uxoB-5y6gA:
undetectable