SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y6h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 5y6h FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		4 / 8 LEU A  32
ASN A  62
VAL A  65
GLY A  37
 None
 0.72A 3dcjB-5y6hA:
undetectable		 3dcjB-5y6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 5y6h FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		5 / 12 LEU A 108
LEU A  23
THR A  77
ALA A  75
ILE A  73
 None
 0.98A 4o2bB-5y6hA:
undetectable		 4o2bB-5y6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5y6h FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		5 / 12 LEU A 108
LEU A  23
THR A  77
ALA A  75
ILE A  73
 None
 0.99A 5mioB-5y6hA:
undetectable		 5mioB-5y6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5y6h FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		4 / 6 LEU A  17
LEU A  20
ARG A  21
HIS A  24
 None
 0.87A 6e43A-5y6hA:
undetectable		 6e43A-5y6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5y6h FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		4 / 6 LEU A  17
LEU A  20
ARG A  21
HIS A  24
 None
 0.87A 6e43B-5y6hA:
undetectable		 6e43B-5y6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5y6h FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		4 / 6 LEU A  17
LEU A  20
ARG A  21
HIS A  24
 None
 0.91A 6e43C-5y6hA:
undetectable		 6e43C-5y6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5y6h FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		4 / 6 LEU A  17
LEU A  20
ARG A  21
HIS A  24
 None
 0.78A 6e43D-5y6hA:
undetectable		 6e43D-5y6hA:
undetectable