SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y6i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5y6i -
(-) 		5 / 12 LEU A  94
ALA A  97
THR A 252
VAL A 216
LEU A 108
 None
 1.28A 1cbrA-5y6iA:
undetectable		 1cbrA-5y6iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5y6i -
(-) 		4 / 4 VAL A 137
THR A 138
VAL A 124
GLY A 141
 None
 1.14A 2p2fB-5y6iA:
undetectable		 2p2fB-5y6iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 5y6i -
(-) 		4 / 4 ALA A 224
VAL A 226
PHE A 217
THR A 252
 None
 1.17A 2pkkA-5y6iA:
undetectable		 2pkkA-5y6iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 5y6i -
(-) 		5 / 10 ARG A 247
ALA A 244
LEU A 198
LEU A 212
VAL A 229
 None
 0.99A 3o02A-5y6iA:
undetectable
3o02B-5y6iA:
undetectable		 3o02A-5y6iA:
undetectable
3o02B-5y6iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 5y6i -
(-) 		5 / 9 VAL A 125
VAL A 230
ALA A 211
VAL A 226
ALA A 115
 None
 1.26A 4oqrA-5y6iA:
undetectable		 4oqrA-5y6iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5y6i -
(-) 		4 / 4 VAL A 229
ALA A 211
PHE A 113
THR A 151
 None
 1.49A 4z4fA-5y6iA:
undetectable		 4z4fA-5y6iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5y6i -
(-) 		4 / 4 VAL A 229
ALA A 211
PHE A 113
THR A 151
 None
 1.46A 4z4hA-5y6iA:
undetectable		 4z4hA-5y6iA:
undetectable