SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y6j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 5y6j NUCLEOPROTEIN
(Tomato
spotted
wilt
orthotospovirus) 		4 / 8 ILE A 100
LEU A  96
PHE A  74
GLY A  75
 None
 1.03A 1os6A-5y6jA:
undetectable		 1os6A-5y6jA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 5y6j NUCLEOPROTEIN
(Tomato
spotted
wilt
orthotospovirus) 		5 / 12 ALA A 189
LEU A 190
VAL A 164
ALA A 216
LEU A 219
 None
 1.03A 3ozuA-5y6jA:
2.8		 3ozuA-5y6jA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 5y6j NUCLEOPROTEIN
(Tomato
spotted
wilt
orthotospovirus) 		4 / 8 ILE A 100
LEU A  96
PHE A  74
GLY A  75
 None
 1.00A 3selX-5y6jA:
undetectable		 3selX-5y6jA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 5y6j NUCLEOPROTEIN
(Tomato
spotted
wilt
orthotospovirus) 		4 / 6 ILE A 100
LEU A  96
PHE A  74
GLY A  75
 None
 0.90A 3sj1X-5y6jA:
undetectable		 3sj1X-5y6jA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 5y6j NUCLEOPROTEIN
(Tomato
spotted
wilt
orthotospovirus) 		4 / 7 ILE A 100
LEU A  96
PHE A  74
GLY A  75
 None
 0.97A 4hbfA-5y6jA:
undetectable		 4hbfA-5y6jA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5y6j NUCLEOPROTEIN
(Tomato
spotted
wilt
orthotospovirus) 		4 / 7 ILE A 100
LEU A  96
PHE A  74
GLY A  75
 None
 1.01A 4hc3A-5y6jA:
undetectable		 4hc3A-5y6jA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5y6j NUCLEOPROTEIN
(Tomato
spotted
wilt
orthotospovirus) 		5 / 12 LEU A 150
ALA A 167
TYR A 215
ILE A 162
LEU A 132
 None
 1.09A 5h8tA-5y6jA:
undetectable		 5h8tA-5y6jA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5y6j NUCLEOPROTEIN
(Tomato
spotted
wilt
orthotospovirus) 		5 / 12 LEU A 150
ALA A 167
TYR A 215
ILE A 162
LEU A 132
 None
 1.13A 5ljeA-5y6jA:
undetectable		 5ljeA-5y6jA:
20.90