SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 LEU A  64
GLN A  45
MET B   1
ARG B 122
LEU B  27
 None
 1.47A 1a28A-5y6qA:
undetectable		 1a28A-5y6qA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 5 LEU A 137
SER A  62
LEU A  27
GLY A  49
 None
None
None
FES  A 201 (-3.6A)
 1.08A 1a4lB-5y6qA:
undetectable		 1a4lB-5y6qA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 GLY A 141
GLY C 683
ILE C 745
THR C 722
ILE C 720
 None
 1.05A 1c6zA-5y6qA:
undetectable		 1c6zA-5y6qA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.41A 1c9sA-5y6qC:
undetectable
1c9sK-5y6qC:
undetectable		 1c9sA-5y6qC:
undetectable
1c9sK-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 1c9sA-5y6qC:
undetectable
1c9sB-5y6qC:
undetectable		 1c9sA-5y6qC:
undetectable
1c9sB-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 1c9sB-5y6qC:
undetectable
1c9sC-5y6qC:
undetectable		 1c9sB-5y6qC:
undetectable
1c9sC-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 1c9sC-5y6qC:
undetectable
1c9sD-5y6qC:
undetectable		 1c9sC-5y6qC:
undetectable
1c9sD-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 1c9sD-5y6qC:
undetectable
1c9sE-5y6qC:
undetectable		 1c9sD-5y6qC:
undetectable
1c9sE-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 1c9sE-5y6qC:
undetectable
1c9sF-5y6qC:
undetectable		 1c9sE-5y6qC:
undetectable
1c9sF-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 1c9sF-5y6qC:
undetectable
1c9sG-5y6qC:
undetectable		 1c9sF-5y6qC:
undetectable
1c9sG-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 1c9sG-5y6qC:
undetectable
1c9sH-5y6qC:
undetectable		 1c9sG-5y6qC:
undetectable
1c9sH-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 1c9sH-5y6qC:
undetectable
1c9sI-5y6qC:
undetectable		 1c9sH-5y6qC:
undetectable
1c9sI-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 1c9sJ-5y6qC:
undetectable
1c9sK-5y6qC:
undetectable		 1c9sJ-5y6qC:
undetectable
1c9sK-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.35A 1c9sL-5y6qC:
undetectable
1c9sM-5y6qC:
undetectable		 1c9sL-5y6qC:
undetectable
1c9sM-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 1c9sM-5y6qC:
undetectable
1c9sN-5y6qC:
undetectable		 1c9sM-5y6qC:
undetectable
1c9sN-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 1c9sO-5y6qC:
undetectable
1c9sP-5y6qC:
undetectable		 1c9sO-5y6qC:
undetectable
1c9sP-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 1c9sS-5y6qC:
undetectable
1c9sT-5y6qC:
undetectable		 1c9sS-5y6qC:
undetectable
1c9sT-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 ILE A 118
PHE A  95
ARG A  93
GLN A 152
ILE A 147
 None
 1.12A 1drfA-5y6qA:
undetectable		 1drfA-5y6qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.39A 1gtfA-5y6qC:
undetectable
1gtfK-5y6qC:
undetectable		 1gtfA-5y6qC:
undetectable
1gtfK-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 1gtfA-5y6qC:
undetectable
1gtfB-5y6qC:
undetectable		 1gtfA-5y6qC:
undetectable
1gtfB-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 1gtfB-5y6qC:
undetectable
1gtfC-5y6qC:
undetectable		 1gtfB-5y6qC:
undetectable
1gtfC-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 1gtfC-5y6qC:
undetectable
1gtfD-5y6qC:
undetectable		 1gtfC-5y6qC:
undetectable
1gtfD-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 1gtfE-5y6qC:
undetectable
1gtfF-5y6qC:
undetectable		 1gtfE-5y6qC:
undetectable
1gtfF-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 1gtfF-5y6qC:
undetectable
1gtfG-5y6qC:
undetectable		 1gtfF-5y6qC:
undetectable
1gtfG-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 1gtfG-5y6qC:
undetectable
1gtfH-5y6qC:
undetectable		 1gtfG-5y6qC:
undetectable
1gtfH-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 1gtfH-5y6qC:
undetectable
1gtfI-5y6qC:
undetectable		 1gtfH-5y6qC:
undetectable
1gtfI-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 1gtfI-5y6qC:
undetectable
1gtfJ-5y6qC:
undetectable		 1gtfI-5y6qC:
undetectable
1gtfJ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 1gtfO-5y6qC:
undetectable
1gtfP-5y6qC:
undetectable		 1gtfO-5y6qC:
undetectable
1gtfP-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.35A 1gtfP-5y6qC:
undetectable
1gtfQ-5y6qC:
undetectable		 1gtfP-5y6qC:
undetectable
1gtfQ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.34A 1gtfT-5y6qC:
undetectable
1gtfU-5y6qC:
undetectable		 1gtfT-5y6qC:
undetectable
1gtfU-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 1gtfU-5y6qC:
undetectable
1gtfV-5y6qC:
undetectable		 1gtfU-5y6qC:
undetectable
1gtfV-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.35A 1gtfL-5y6qC:
undetectable
1gtfV-5y6qC:
undetectable		 1gtfL-5y6qC:
undetectable
1gtfV-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 VAL C 258
GLY C 489
ALA C 486
THR C 490
ILE C 488
 None
MCN  C 802 (-3.3A)
None
MCN  C 802 (-3.6A)
MCN  C 802 (-4.3A)
 1.24A 1gtnL-5y6qC:
undetectable
1gtnM-5y6qC:
undetectable		 1gtnL-5y6qC:
undetectable
1gtnM-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.34A 1gtnN-5y6qC:
undetectable
1gtnO-5y6qC:
undetectable		 1gtnN-5y6qC:
undetectable
1gtnO-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.31A 1gtnR-5y6qC:
undetectable
1gtnS-5y6qC:
undetectable		 1gtnR-5y6qC:
undetectable
1gtnS-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 4 GLY C 491
LEU C 671
GLY C 489
ARG C  40
 MCN  C 802 (-3.6A)
MCN  C 802 (-3.9A)
MCN  C 802 (-3.3A)
None
 1.18A 1j7kA-5y6qC:
undetectable		 1j7kA-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		5 / 11 LEU C 706
LEU C 710
ALA B 243
VAL C 711
GLN A  47
 None
None
GOL  B 407 ( 3.7A)
None
None
 1.40A 1kt6A-5y6qC:
undetectable		 1kt6A-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		5 / 11 LEU C 706
LEU C 710
ALA B 243
VAL C 711
GLN A  47
 None
None
GOL  B 407 ( 3.7A)
None
None
 1.36A 1kt7A-5y6qC:
undetectable		 1kt7A-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		3 / 3 ARG B 113
ARG B 209
ARG B 115
 SO4  B 403 ( 2.4A)
None
FAD  B 401 ( 3.5A)
 1.09A 1l7fA-5y6qB:
undetectable		 1l7fA-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		3 / 3 ASP B 193
ASP B 207
LYS B 270
 None
 1.06A 1lqtB-5y6qB:
undetectable		 1lqtB-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		3 / 3 ASP B 193
ASP B 207
LYS B 270
 None
 1.07A 1lquB-5y6qB:
undetectable		 1lquB-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 LEU C 299
LYS C 265
TYR C 206
GLY C 261
TYR C 269
 None
None
None
MCN  C 802 (-3.4A)
None
 1.30A 1lwcA-5y6qC:
undetectable		 1lwcA-5y6qC:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 ALA C 687
LEU C 767
PRO C 203
ALA C 749
GLY C 747
 None
 1.30A 1mjqG-5y6qC:
undetectable
1mjqH-5y6qC:
undetectable		 1mjqG-5y6qC:
undetectable
1mjqH-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY A 141
ALA A 142
ASP A  99
GLY A 104
ILE A 146
 None
None
None
FES  A 202 (-4.1A)
None
 0.97A 1muiA-5y6qA:
undetectable		 1muiA-5y6qA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 PHE A  95
SER A 113
ARG A  59
ALA A 149
 None
 1.19A 1rqpC-5y6qA:
undetectable		 1rqpC-5y6qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 PHE A  95
SER A 113
ARG A  59
ALA A 149
 None
 1.16A 1rqpA-5y6qA:
undetectable		 1rqpA-5y6qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.43A 1utdA-5y6qC:
undetectable
1utdB-5y6qC:
undetectable		 1utdA-5y6qC:
undetectable
1utdB-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.39A 1utdC-5y6qC:
undetectable
1utdD-5y6qC:
undetectable		 1utdC-5y6qC:
undetectable
1utdD-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.41A 1utdD-5y6qC:
undetectable
1utdE-5y6qC:
undetectable		 1utdD-5y6qC:
undetectable
1utdE-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 1utdN-5y6qC:
undetectable
1utdO-5y6qC:
undetectable		 1utdN-5y6qC:
undetectable
1utdO-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.35A 1utdQ-5y6qC:
undetectable
1utdR-5y6qC:
undetectable		 1utdQ-5y6qC:
undetectable
1utdR-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.34A 1utdR-5y6qC:
undetectable
1utdS-5y6qC:
undetectable		 1utdR-5y6qC:
undetectable
1utdS-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 5 ILE B  72
SER B  93
ARG B 103
LEU B  77
 None
None
GOL  B 406 (-4.1A)
None
 1.17A 1y0xX-5y6qB:
undetectable		 1y0xX-5y6qB:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 ALA C 148
ALA C 149
LEU C  68
ILE C 136
ALA C  85
 None
 0.97A 2aclG-5y6qC:
undetectable		 2aclG-5y6qC:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 GLY C  43
GLY C 259
GLU C 211
ILE C  48
ALA C  51
 None
 1.00A 2fk8A-5y6qC:
undetectable		 2fk8A-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		3 / 3 SER C 328
THR C 344
GLN C 324
 None
 0.81A 2fk8A-5y6qC:
undetectable		 2fk8A-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY A 141
ALA A 142
ASP A  99
GLY A 104
ILE A 146
 None
None
None
FES  A 202 (-4.1A)
None
 0.88A 2idwB-5y6qA:
undetectable		 2idwB-5y6qA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 LEU C  68
GLY C 135
ILE C 134
ILE C  77
VAL C 152
 None
 0.96A 2kawA-5y6qC:
undetectable		 2kawA-5y6qC:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 6 PHE C 296
ARG C 204
ASN C 130
ASN B 146
 None
 1.29A 2nyrA-5y6qC:
undetectable		 2nyrA-5y6qC:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 6 GLY B 110
GLY B 164
PHE B 195
PHE B 194
 FAD  B 401 (-3.2A)
FAD  B 401 (-3.4A)
None
None
 0.96A 2qx6A-5y6qB:
undetectable
2qx6B-5y6qB:
undetectable		 2qx6A-5y6qB:
21.74
2qx6B-5y6qB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1162_1
(ALLERGEN ARG R 1)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 4 GLU B 282
ASP B 174
HIS B 261
GLU B 278
 None
 1.47A 2x45A-5y6qB:
undetectable		 2x45A-5y6qB:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		3 / 3 GLU B 282
HIS B 261
GLU B 278
 None
 0.85A 2x45B-5y6qB:
undetectable		 2x45B-5y6qB:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 LEU A  64
GLN A  45
MET B   1
ARG B 122
LEU B  27
 None
 1.39A 3d90A-5y6qA:
undetectable		 3d90A-5y6qA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY A 141
ALA A 142
ASP A  99
GLY A 104
ILE A 146
 None
None
None
FES  A 202 (-4.1A)
None
 0.88A 3ekvA-5y6qA:
undetectable		 3ekvA-5y6qA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 ALA C 217
VAL C 272
ILE C 240
ILE C 254
PRO C 229
 None
 1.26A 3el4B-5y6qC:
undetectable		 3el4B-5y6qC:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 ALA C 217
ILE C 216
PRO C  59
PRO C  62
 None
 0.97A 3fxrA-5y6qC:
undetectable		 3fxrA-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 4 ILE A  78
ARG A  93
ILE C  48
THR A  76
 None
 1.19A 3ia4C-5y6qA:
undetectable		 3ia4C-5y6qA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 GLY C  49
CYH A  48
CYH A 138
PHE C 262
 None
FES  A 201 (-2.2A)
FES  A 202 (-2.2A)
MCN  C 802 (-3.3A)
 1.04A 3ko0D-5y6qC:
undetectable
3ko0E-5y6qC:
undetectable		 3ko0D-5y6qC:
20.00
3ko0E-5y6qC:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 GLY C  49
CYH A  48
CYH A 138
PHE C 262
 None
FES  A 201 (-2.2A)
FES  A 202 (-2.2A)
MCN  C 802 (-3.3A)
 1.05A 3ko0B-5y6qC:
undetectable
3ko0J-5y6qC:
undetectable		 3ko0B-5y6qC:
20.00
3ko0J-5y6qC:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 ILE C 253
THR C 518
ASP C 517
VAL C 226
ILE C 224
 None
GOL  C 811 (-4.8A)
None
None
None
 1.14A 3kpdB-5y6qC:
undetectable		 3kpdB-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		3 / 3 ARG C 371
ASP A  99
GLN C 498
 MCN  C 802 (-4.2A)
None
None
 0.74A 3lcvB-5y6qC:
undetectable		 3lcvB-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 6 ILE A 146
ILE C 745
GLY C 678
VAL C 711
 None
 0.90A 3n3iA-5y6qA:
undetectable		 3n3iA-5y6qA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY A 141
ALA A 142
ASP A  99
GLY A 104
ILE A 146
 None
None
None
FES  A 202 (-4.1A)
None
 0.96A 3oxvA-5y6qA:
undetectable		 3oxvA-5y6qA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY A 141
ALA A 142
ASP A  99
GLY A 104
ILE A 146
 None
None
None
FES  A 202 (-4.1A)
None
 0.97A 3oxvC-5y6qA:
undetectable		 3oxvC-5y6qA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 6 ILE B 262
GLU B 278
PHE B 173
ALA B 172
 None
 0.98A 3pgyA-5y6qB:
undetectable
3pgyB-5y6qB:
undetectable		 3pgyA-5y6qB:
undetectable
3pgyB-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 7 ILE B 319
LEU B 264
GLU B 278
ALA B 172
 None
 0.86A 3r9tB-5y6qB:
undetectable		 3r9tB-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_D_DXCD92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 5 VAL C 619
GLU C 514
LYS C 470
PHE C 606
 None
 1.27A 3rv5C-5y6qC:
0.1
3rv5D-5y6qC:
0.0		 3rv5C-5y6qC:
undetectable
3rv5D-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		3 / 3 HIS C 634
SER C 378
GLU C 375
 None
None
GOL  C 814 (-3.2A)
 0.89A 3s8pA-5y6qC:
undetectable		 3s8pA-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 GLY C 524
VAL C 267
ALA C 484
THR C 518
ALA C 519
 None
None
GOL  C 811 ( 3.7A)
GOL  C 811 (-4.8A)
None
 0.96A 3sugA-5y6qC:
undetectable		 3sugA-5y6qC:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 GLY B 164
ASP B 165
LYS B 232
VAL B 318
ASN B 308
 FAD  B 401 (-3.4A)
FAD  B 401 (-3.5A)
FAD  B 401 (-2.7A)
None
None
 1.11A 4a81A-5y6qB:
undetectable		 4a81A-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 GLU B 282
LEU B 323
ALA B 247
GLU B 278
ARG B 273
 None
 1.48A 4cpzB-5y6qB:
undetectable		 4cpzB-5y6qB:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		3 / 3 ARG C 620
TRP C 232
GLY C 235
 GOL  C 811 (-4.2A)
None
None
 0.98A 4e7cA-5y6qC:
undetectable		 4e7cA-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 7 ALA A 155
ALA A 123
GLY A 124
ILE A 150
 None
 0.59A 4eatA-5y6qA:
undetectable		 4eatA-5y6qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 VAL A  53
THR A 107
PRO A 108
ASN A 136
ILE A 150
 None
 1.45A 4eb6B-5y6qA:
undetectable
4eb6C-5y6qA:
undetectable		 4eb6B-5y6qA:
11.94
4eb6C-5y6qA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 HIS C 213
GLU C 211
ASN C 207
GLY C 261
 None
None
None
MCN  C 802 (-3.4A)
 0.96A 4f93B-5y6qC:
undetectable		 4f93B-5y6qC:
4.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 PHE B 194
ILE B 217
PHE B 195
GLY B 110
 None
None
None
FAD  B 401 (-3.2A)
 0.98A 4fgjA-5y6qB:
undetectable
4fgjB-5y6qB:
undetectable		 4fgjA-5y6qB:
undetectable
4fgjB-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 5 GLY C 113
GLY C 112
ASN C 623
GLU C 242
 None
 1.31A 4fglC-5y6qC:
undetectable		 4fglC-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 ASP C 662
SER C 663
ASN C 724
GLY C 736
 None
 0.98A 4fo4A-5y6qC:
undetectable		 4fo4A-5y6qC:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 5 LEU C 400
ARG C 401
ILE C 322
ASN C 197
 None
 1.02A 4i00A-5y6qC:
undetectable		 4i00A-5y6qC:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 4 VAL B 179
THR B 186
GLU B 212
GLU B 185
 None
 1.38A 4l78A-5y6qB:
undetectable		 4l78A-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 GLY C 692
LEU C 710
TYR C 709
ASN C 703
 None
 1.01A 4m5mA-5y6qC:
undetectable		 4m5mA-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N6P_A_JMSA713_1
(LACTOTRANSFERRIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 4 HIS C 271
ALA C 273
VAL C 272
GLU C 239
 None
 1.38A 4n6pA-5y6qC:
undetectable		 4n6pA-5y6qC:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 GLY A 141
GLY C 683
ILE C 745
THR C 722
ILE C 720
 None
 0.98A 4njvB-5y6qA:
undetectable		 4njvB-5y6qA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		3 / 3 ARG B 103
GLN B  96
GLU A 131
 GOL  B 406 (-4.1A)
None
None
 0.93A 4tvtA-5y6qB:
undetectable		 4tvtA-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		4 / 7 ARG C 445
PHE B 292
ARG B 321
ASP C 648
 None
 1.45A 5a06A-5y6qC:
undetectable		 5a06A-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		4 / 7 ARG C 445
PHE B 292
ARG B 321
ASP C 648
 None
 1.44A 5a06C-5y6qC:
undetectable		 5a06C-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		4 / 7 ARG C 445
PHE B 292
ARG B 321
ASP C 648
 None
 1.44A 5a06D-5y6qC:
undetectable		 5a06D-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		4 / 7 ARG C 445
PHE B 292
ARG B 321
ASP C 648
 None
 1.44A 5a06E-5y6qC:
undetectable		 5a06E-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		4 / 7 ARG C 445
PHE B 292
ARG B 321
ASP C 648
 None
 1.44A 5a06F-5y6qC:
undetectable		 5a06F-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		5 / 12 LEU A  30
VAL A  60
VAL A  53
THR A  39
MET B 105
 None
 1.11A 5bykA-5y6qA:
undetectable		 5bykA-5y6qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		5 / 12 GLY C  49
LEU A  81
GLY A 109
GLY C 259
PHE A 101
 None
 1.12A 5d4uB-5y6qC:
undetectable		 5d4uB-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eeuA-5y6qC:
undetectable
5eeuB-5y6qC:
undetectable		 5eeuA-5y6qC:
undetectable
5eeuB-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5eeuB-5y6qC:
undetectable
5eeuC-5y6qC:
undetectable		 5eeuB-5y6qC:
undetectable
5eeuC-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eeuD-5y6qC:
undetectable
5eeuE-5y6qC:
undetectable		 5eeuD-5y6qC:
undetectable
5eeuE-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eeuE-5y6qC:
undetectable
5eeuF-5y6qC:
undetectable		 5eeuE-5y6qC:
undetectable
5eeuF-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eeuG-5y6qC:
undetectable
5eeuH-5y6qC:
undetectable		 5eeuG-5y6qC:
undetectable
5eeuH-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5eeuH-5y6qC:
undetectable
5eeuI-5y6qC:
undetectable		 5eeuH-5y6qC:
undetectable
5eeuI-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.39A 5eeuN-5y6qC:
undetectable
5eeuO-5y6qC:
undetectable		 5eeuN-5y6qC:
undetectable
5eeuO-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eeuP-5y6qC:
undetectable
5eeuQ-5y6qC:
undetectable		 5eeuP-5y6qC:
undetectable
5eeuQ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eeuR-5y6qC:
undetectable
5eeuS-5y6qC:
undetectable		 5eeuR-5y6qC:
undetectable
5eeuS-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eeuS-5y6qC:
undetectable
5eeuT-5y6qC:
undetectable		 5eeuS-5y6qC:
undetectable
5eeuT-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eeuT-5y6qC:
undetectable
5eeuU-5y6qC:
undetectable		 5eeuT-5y6qC:
undetectable
5eeuU-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5eeuU-5y6qC:
undetectable
5eeuV-5y6qC:
undetectable		 5eeuU-5y6qC:
undetectable
5eeuV-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.37A 5eevB-5y6qC:
undetectable
5eevC-5y6qC:
undetectable		 5eevB-5y6qC:
undetectable
5eevC-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eevD-5y6qC:
undetectable
5eevE-5y6qC:
undetectable		 5eevD-5y6qC:
undetectable
5eevE-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eevE-5y6qC:
undetectable
5eevF-5y6qC:
undetectable		 5eevE-5y6qC:
undetectable
5eevF-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eevG-5y6qC:
undetectable
5eevH-5y6qC:
undetectable		 5eevG-5y6qC:
undetectable
5eevH-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5eevH-5y6qC:
undetectable
5eevI-5y6qC:
undetectable		 5eevH-5y6qC:
undetectable
5eevI-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.39A 5eevN-5y6qC:
undetectable
5eevO-5y6qC:
undetectable		 5eevN-5y6qC:
undetectable
5eevO-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eevP-5y6qC:
undetectable
5eevQ-5y6qC:
undetectable		 5eevP-5y6qC:
undetectable
5eevQ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eevR-5y6qC:
undetectable
5eevS-5y6qC:
undetectable		 5eevR-5y6qC:
undetectable
5eevS-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eevS-5y6qC:
undetectable
5eevT-5y6qC:
undetectable		 5eevS-5y6qC:
undetectable
5eevT-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eevT-5y6qC:
undetectable
5eevU-5y6qC:
undetectable		 5eevT-5y6qC:
undetectable
5eevU-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5eevU-5y6qC:
undetectable
5eevV-5y6qC:
undetectable		 5eevU-5y6qC:
undetectable
5eevV-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5eewB-5y6qC:
undetectable
5eewC-5y6qC:
undetectable		 5eewB-5y6qC:
undetectable
5eewC-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eewD-5y6qC:
undetectable
5eewE-5y6qC:
undetectable		 5eewD-5y6qC:
undetectable
5eewE-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eewE-5y6qC:
undetectable
5eewF-5y6qC:
undetectable		 5eewE-5y6qC:
undetectable
5eewF-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eewG-5y6qC:
undetectable
5eewH-5y6qC:
undetectable		 5eewG-5y6qC:
undetectable
5eewH-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5eewH-5y6qC:
undetectable
5eewI-5y6qC:
undetectable		 5eewH-5y6qC:
undetectable
5eewI-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.39A 5eewN-5y6qC:
undetectable
5eewO-5y6qC:
undetectable		 5eewN-5y6qC:
undetectable
5eewO-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eewP-5y6qC:
undetectable
5eewQ-5y6qC:
undetectable		 5eewP-5y6qC:
undetectable
5eewQ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eewR-5y6qC:
undetectable
5eewS-5y6qC:
undetectable		 5eewR-5y6qC:
undetectable
5eewS-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eewS-5y6qC:
undetectable
5eewT-5y6qC:
undetectable		 5eewS-5y6qC:
undetectable
5eewT-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eewT-5y6qC:
undetectable
5eewU-5y6qC:
undetectable		 5eewT-5y6qC:
undetectable
5eewU-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5eewU-5y6qC:
undetectable
5eewV-5y6qC:
undetectable		 5eewU-5y6qC:
undetectable
5eewV-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5eexB-5y6qC:
undetectable
5eexC-5y6qC:
undetectable		 5eexB-5y6qC:
undetectable
5eexC-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eexD-5y6qC:
undetectable
5eexE-5y6qC:
undetectable		 5eexD-5y6qC:
undetectable
5eexE-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eexE-5y6qC:
undetectable
5eexF-5y6qC:
undetectable		 5eexE-5y6qC:
undetectable
5eexF-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 5eexG-5y6qC:
undetectable
5eexH-5y6qC:
undetectable		 5eexG-5y6qC:
undetectable
5eexH-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5eexH-5y6qC:
undetectable
5eexI-5y6qC:
undetectable		 5eexH-5y6qC:
undetectable
5eexI-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.36A 5eexI-5y6qC:
undetectable
5eexJ-5y6qC:
undetectable		 5eexI-5y6qC:
undetectable
5eexJ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.39A 5eexN-5y6qC:
undetectable
5eexO-5y6qC:
undetectable		 5eexN-5y6qC:
undetectable
5eexO-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eexP-5y6qC:
undetectable
5eexQ-5y6qC:
undetectable		 5eexP-5y6qC:
undetectable
5eexQ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.41A 5eexQ-5y6qC:
undetectable
5eexR-5y6qC:
undetectable		 5eexQ-5y6qC:
undetectable
5eexR-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eexR-5y6qC:
undetectable
5eexS-5y6qC:
undetectable		 5eexR-5y6qC:
undetectable
5eexS-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eexS-5y6qC:
undetectable
5eexT-5y6qC:
undetectable		 5eexS-5y6qC:
undetectable
5eexT-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eexT-5y6qC:
undetectable
5eexU-5y6qC:
undetectable		 5eexT-5y6qC:
undetectable
5eexU-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5eexU-5y6qC:
undetectable
5eexV-5y6qC:
undetectable		 5eexU-5y6qC:
undetectable
5eexV-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.37A 5eeyB-5y6qC:
undetectable
5eeyC-5y6qC:
undetectable		 5eeyB-5y6qC:
undetectable
5eeyC-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eeyD-5y6qC:
undetectable
5eeyE-5y6qC:
undetectable		 5eeyD-5y6qC:
undetectable
5eeyE-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eeyE-5y6qC:
undetectable
5eeyF-5y6qC:
undetectable		 5eeyE-5y6qC:
undetectable
5eeyF-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eeyG-5y6qC:
undetectable
5eeyH-5y6qC:
undetectable		 5eeyG-5y6qC:
undetectable
5eeyH-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5eeyH-5y6qC:
undetectable
5eeyI-5y6qC:
undetectable		 5eeyH-5y6qC:
undetectable
5eeyI-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.36A 5eeyI-5y6qC:
undetectable
5eeyJ-5y6qC:
undetectable		 5eeyI-5y6qC:
undetectable
5eeyJ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.39A 5eeyN-5y6qC:
undetectable
5eeyO-5y6qC:
undetectable		 5eeyN-5y6qC:
undetectable
5eeyO-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eeyP-5y6qC:
undetectable
5eeyQ-5y6qC:
undetectable		 5eeyP-5y6qC:
undetectable
5eeyQ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.41A 5eeyQ-5y6qC:
undetectable
5eeyR-5y6qC:
undetectable		 5eeyQ-5y6qC:
undetectable
5eeyR-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eeyR-5y6qC:
undetectable
5eeyS-5y6qC:
undetectable		 5eeyR-5y6qC:
undetectable
5eeyS-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eeyS-5y6qC:
undetectable
5eeyT-5y6qC:
undetectable		 5eeyS-5y6qC:
undetectable
5eeyT-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eeyT-5y6qC:
undetectable
5eeyU-5y6qC:
undetectable		 5eeyT-5y6qC:
undetectable
5eeyU-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5eeyU-5y6qC:
undetectable
5eeyV-5y6qC:
undetectable		 5eeyU-5y6qC:
undetectable
5eeyV-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.37A 5eezB-5y6qC:
undetectable
5eezC-5y6qC:
undetectable		 5eezB-5y6qC:
undetectable
5eezC-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eezD-5y6qC:
undetectable
5eezE-5y6qC:
undetectable		 5eezD-5y6qC:
undetectable
5eezE-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5eezE-5y6qC:
undetectable
5eezF-5y6qC:
undetectable		 5eezE-5y6qC:
undetectable
5eezF-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 5eezG-5y6qC:
undetectable
5eezH-5y6qC:
undetectable		 5eezG-5y6qC:
undetectable
5eezH-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5eezH-5y6qC:
undetectable
5eezI-5y6qC:
undetectable		 5eezH-5y6qC:
undetectable
5eezI-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.36A 5eezI-5y6qC:
undetectable
5eezJ-5y6qC:
undetectable		 5eezI-5y6qC:
undetectable
5eezJ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.39A 5eezN-5y6qC:
undetectable
5eezO-5y6qC:
undetectable		 5eezN-5y6qC:
undetectable
5eezO-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eezP-5y6qC:
undetectable
5eezQ-5y6qC:
undetectable		 5eezP-5y6qC:
undetectable
5eezQ-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.41A 5eezQ-5y6qC:
undetectable
5eezR-5y6qC:
undetectable		 5eezQ-5y6qC:
undetectable
5eezR-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eezR-5y6qC:
undetectable
5eezS-5y6qC:
undetectable		 5eezR-5y6qC:
undetectable
5eezS-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5eezS-5y6qC:
undetectable
5eezT-5y6qC:
undetectable		 5eezS-5y6qC:
undetectable
5eezT-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5eezT-5y6qC:
undetectable
5eezU-5y6qC:
undetectable		 5eezT-5y6qC:
undetectable
5eezU-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5eezU-5y6qC:
undetectable
5eezV-5y6qC:
undetectable		 5eezU-5y6qC:
undetectable
5eezV-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.37A 5ef0B-5y6qC:
undetectable
5ef0C-5y6qC:
undetectable		 5ef0B-5y6qC:
undetectable
5ef0C-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5ef0D-5y6qC:
undetectable
5ef0E-5y6qC:
undetectable		 5ef0D-5y6qC:
undetectable
5ef0E-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5ef0E-5y6qC:
undetectable
5ef0F-5y6qC:
undetectable		 5ef0E-5y6qC:
undetectable
5ef0F-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 5ef0G-5y6qC:
undetectable
5ef0H-5y6qC:
undetectable		 5ef0G-5y6qC:
undetectable
5ef0H-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5ef0H-5y6qC:
undetectable
5ef0I-5y6qC:
undetectable		 5ef0H-5y6qC:
undetectable
5ef0I-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.36A 5ef0I-5y6qC:
undetectable
5ef0J-5y6qC:
undetectable		 5ef0I-5y6qC:
undetectable
5ef0J-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.39A 5ef0N-5y6qC:
undetectable
5ef0O-5y6qC:
undetectable		 5ef0N-5y6qC:
undetectable
5ef0O-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef0P-5y6qC:
undetectable
5ef0Q-5y6qC:
undetectable		 5ef0P-5y6qC:
undetectable
5ef0Q-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.41A 5ef0Q-5y6qC:
undetectable
5ef0R-5y6qC:
undetectable		 5ef0Q-5y6qC:
undetectable
5ef0R-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef0R-5y6qC:
undetectable
5ef0S-5y6qC:
undetectable		 5ef0R-5y6qC:
undetectable
5ef0S-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5ef0S-5y6qC:
undetectable
5ef0T-5y6qC:
undetectable		 5ef0S-5y6qC:
undetectable
5ef0T-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef0T-5y6qC:
undetectable
5ef0U-5y6qC:
undetectable		 5ef0T-5y6qC:
undetectable
5ef0U-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5ef0U-5y6qC:
undetectable
5ef0V-5y6qC:
undetectable		 5ef0U-5y6qC:
undetectable
5ef0V-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.37A 5ef1B-5y6qC:
undetectable
5ef1C-5y6qC:
undetectable		 5ef1B-5y6qC:
undetectable
5ef1C-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5ef1D-5y6qC:
undetectable
5ef1E-5y6qC:
undetectable		 5ef1D-5y6qC:
undetectable
5ef1E-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5ef1E-5y6qC:
undetectable
5ef1F-5y6qC:
undetectable		 5ef1E-5y6qC:
undetectable
5ef1F-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 5ef1G-5y6qC:
undetectable
5ef1H-5y6qC:
undetectable		 5ef1G-5y6qC:
undetectable
5ef1H-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5ef1H-5y6qC:
undetectable
5ef1I-5y6qC:
undetectable		 5ef1H-5y6qC:
undetectable
5ef1I-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.36A 5ef1I-5y6qC:
undetectable
5ef1J-5y6qC:
undetectable		 5ef1I-5y6qC:
undetectable
5ef1J-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5ef1N-5y6qC:
undetectable
5ef1O-5y6qC:
undetectable		 5ef1N-5y6qC:
undetectable
5ef1O-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef1P-5y6qC:
undetectable
5ef1Q-5y6qC:
undetectable		 5ef1P-5y6qC:
undetectable
5ef1Q-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.41A 5ef1Q-5y6qC:
undetectable
5ef1R-5y6qC:
undetectable		 5ef1Q-5y6qC:
undetectable
5ef1R-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef1R-5y6qC:
undetectable
5ef1S-5y6qC:
undetectable		 5ef1R-5y6qC:
undetectable
5ef1S-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5ef1S-5y6qC:
undetectable
5ef1T-5y6qC:
undetectable		 5ef1S-5y6qC:
undetectable
5ef1T-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef1T-5y6qC:
undetectable
5ef1U-5y6qC:
undetectable		 5ef1T-5y6qC:
undetectable
5ef1U-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5ef1U-5y6qC:
undetectable
5ef1V-5y6qC:
undetectable		 5ef1U-5y6qC:
undetectable
5ef1V-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5ef2B-5y6qC:
undetectable
5ef2C-5y6qC:
undetectable		 5ef2B-5y6qC:
undetectable
5ef2C-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5ef2D-5y6qC:
undetectable
5ef2E-5y6qC:
undetectable		 5ef2D-5y6qC:
undetectable
5ef2E-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5ef2E-5y6qC:
undetectable
5ef2F-5y6qC:
undetectable		 5ef2E-5y6qC:
undetectable
5ef2F-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 5ef2G-5y6qC:
undetectable
5ef2H-5y6qC:
undetectable		 5ef2G-5y6qC:
undetectable
5ef2H-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5ef2H-5y6qC:
undetectable
5ef2I-5y6qC:
undetectable		 5ef2H-5y6qC:
undetectable
5ef2I-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.36A 5ef2I-5y6qC:
undetectable
5ef2J-5y6qC:
undetectable		 5ef2I-5y6qC:
undetectable
5ef2J-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.39A 5ef2N-5y6qC:
undetectable
5ef2O-5y6qC:
undetectable		 5ef2N-5y6qC:
undetectable
5ef2O-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef2P-5y6qC:
undetectable
5ef2Q-5y6qC:
undetectable		 5ef2P-5y6qC:
undetectable
5ef2Q-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.40A 5ef2Q-5y6qC:
undetectable
5ef2R-5y6qC:
undetectable		 5ef2Q-5y6qC:
undetectable
5ef2R-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef2R-5y6qC:
undetectable
5ef2S-5y6qC:
undetectable		 5ef2R-5y6qC:
undetectable
5ef2S-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5ef2S-5y6qC:
undetectable
5ef2T-5y6qC:
undetectable		 5ef2S-5y6qC:
undetectable
5ef2T-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef2T-5y6qC:
undetectable
5ef2U-5y6qC:
undetectable		 5ef2T-5y6qC:
undetectable
5ef2U-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5ef2U-5y6qC:
undetectable
5ef2V-5y6qC:
undetectable		 5ef2U-5y6qC:
undetectable
5ef2V-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5ef3B-5y6qC:
undetectable
5ef3C-5y6qC:
undetectable		 5ef3B-5y6qC:
undetectable
5ef3C-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5ef3D-5y6qC:
undetectable
5ef3E-5y6qC:
undetectable		 5ef3D-5y6qC:
undetectable
5ef3E-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.40A 5ef3E-5y6qC:
undetectable
5ef3F-5y6qC:
undetectable		 5ef3E-5y6qC:
undetectable
5ef3F-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.39A 5ef3G-5y6qC:
undetectable
5ef3H-5y6qC:
undetectable		 5ef3G-5y6qC:
undetectable
5ef3H-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.38A 5ef3H-5y6qC:
undetectable
5ef3I-5y6qC:
undetectable		 5ef3H-5y6qC:
undetectable
5ef3I-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 11 SER C 276
GLY C  65
ALA C 278
HIS C 271
ILE C 138
 None
 1.36A 5ef3I-5y6qC:
undetectable
5ef3J-5y6qC:
undetectable		 5ef3I-5y6qC:
undetectable
5ef3J-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5ef3N-5y6qC:
undetectable
5ef3O-5y6qC:
undetectable		 5ef3N-5y6qC:
undetectable
5ef3O-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef3P-5y6qC:
undetectable
5ef3Q-5y6qC:
undetectable		 5ef3P-5y6qC:
undetectable
5ef3Q-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 9 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.41A 5ef3Q-5y6qC:
undetectable
5ef3R-5y6qC:
undetectable		 5ef3Q-5y6qC:
undetectable
5ef3R-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef3R-5y6qC:
undetectable
5ef3S-5y6qC:
undetectable		 5ef3R-5y6qC:
undetectable
5ef3S-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.37A 5ef3S-5y6qC:
undetectable
5ef3T-5y6qC:
undetectable		 5ef3S-5y6qC:
undetectable
5ef3T-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.36A 5ef3T-5y6qC:
undetectable
5ef3U-5y6qC:
undetectable		 5ef3T-5y6qC:
undetectable
5ef3U-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 GLY C  65
ALA C 278
HIS C 271
ILE C 138
SER C 276
 None
 1.38A 5ef3U-5y6qC:
undetectable
5ef3V-5y6qC:
undetectable		 5ef3U-5y6qC:
undetectable
5ef3V-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 4 ALA C 217
PRO C 229
LEU C 299
HIS C 271
 None
 1.42A 5eskA-5y6qC:
undetectable		 5eskA-5y6qC:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 THR B 107
LEU B  71
ILE B  50
LEU B  56
 FAD  B 401 (-3.0A)
None
None
None
 0.75A 5g48A-5y6qB:
undetectable		 5g48A-5y6qB:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 ASP B  62
GLY B  69
THR B 107
SER B  67
GLU B 218
 None
None
FAD  B 401 (-3.0A)
None
None
 1.35A 5hfjA-5y6qB:
undetectable		 5hfjA-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 ASP B  62
GLY B  69
THR B 107
SER B  67
GLU B 218
 None
None
FAD  B 401 (-3.0A)
None
None
 1.30A 5hfjC-5y6qB:
undetectable		 5hfjC-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 4 LEU C 767
LEU C 688
GLY C 685
GLU C 690
 None
 1.22A 5hhjA-5y6qC:
undetectable		 5hhjA-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 5 TYR B 230
LYS B 232
GLY B 164
SER B  93
 None
FAD  B 401 (-2.7A)
FAD  B 401 (-3.4A)
None
 1.45A 5jhdJ-5y6qB:
undetectable		 5jhdJ-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 8 GLU C 614
PRO C 607
PRO C 611
ASP C 609
 None
 1.14A 5kf8A-5y6qC:
undetectable		 5kf8A-5y6qC:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		4 / 4 GLY A  72
ALA A  70
MET A  18
THR A  65
 None
 1.47A 5n0sB-5y6qA:
undetectable		 5n0sB-5y6qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 PRO C 121
GLY C 131
GLY C 298
VAL C  67
LEU C  68
 None
 1.15A 5o96E-5y6qC:
undetectable
5o96F-5y6qC:
undetectable		 5o96E-5y6qC:
undetectable
5o96F-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		4 / 8 ASN A 136
SER B  99
ILE B 102
MET B 105
 None
None
FAD  B 401 (-4.6A)
None
 1.03A 5u4sB-5y6qA:
undetectable		 5u4sB-5y6qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 PHE B 195
ILE B 191
ILE B 217
ALA B  70
ILE B 213
 None
None
None
FAD  B 401 ( 4.0A)
FAD  B 401 (-3.5A)
 1.08A 5vceA-5y6qB:
undetectable		 5vceA-5y6qB:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 10 ARG C 442
GLY C 650
THR C 651
ILE C 774
ALA C 759
 SO4  C 804 (-4.1A)
None
None
None
None
 1.27A 5vyhA-5y6qC:
undetectable		 5vyhA-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 ALA B 247
GLY B  92
ILE B 262
ASP B 192
ASP B 165
 None
None
None
None
FAD  B 401 (-3.5A)
 1.25A 5wwsB-5y6qB:
undetectable		 5wwsB-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 ASN C 197
GLY C 312
ALA C 313
LEU C 400
LEU C 393
 None
 1.10A 5xxiA-5y6qC:
undetectable		 5xxiA-5y6qC:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		3 / 3 ARG B 113
PHE B  42
ARG B 115
 SO4  B 403 ( 2.4A)
None
FAD  B 401 ( 3.5A)
 1.08A 5y9yA-5y6qB:
undetectable		 5y9yA-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 TYR B 239
MET B 105
THR A  52
LEU A  61
ARG B 236
 FAD  B 401 (-4.8A)
None
None
FES  A 201 ( 4.3A)
None
 1.28A 6baaE-5y6qB:
undetectable		 6baaE-5y6qB:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 TYR B 239
MET B 105
THR A  52
LEU A  61
ARG B 236
 FAD  B 401 (-4.8A)
None
None
FES  A 201 ( 4.3A)
None
 1.28A 6baaF-5y6qB:
undetectable		 6baaF-5y6qB:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 TYR B 239
MET B 105
THR A  52
LEU A  61
ARG B 236
 FAD  B 401 (-4.8A)
None
None
FES  A 201 ( 4.3A)
None
 1.29A 6baaG-5y6qB:
undetectable		 6baaG-5y6qB:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
SMALL SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 TYR B 239
MET B 105
THR A  52
LEU A  61
ARG B 236
 FAD  B 401 (-4.8A)
None
None
FES  A 201 ( 4.3A)
None
 1.28A 6baaH-5y6qB:
undetectable		 6baaH-5y6qB:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		3 / 3 ARG C 656
LYS C 655
ARG B 321
 None
 1.19A 6c06D-5y6qC:
undetectable		 6c06D-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 5y6q ALDEHYDE OXIDASE
SMALL SUBUNIT
ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400;
Methylobacillus
sp.
KY4400) 		4 / 6 PHE B   4
ARG A  23
ILE A   5
ASP A  21
 None
 1.49A 6dhbA-5y6qB:
undetectable		 6dhbA-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		3 / 3 PHE C 164
ARG C 204
ALA C  73
 None
 0.96A 6ecfB-5y6qC:
undetectable		 6ecfB-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 LEU B  59
ALA B  87
SER B 228
LEU B  77
LEU B 170
 None
 0.84A 6ew0B-5y6qB:
undetectable		 6ew0B-5y6qB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 LEU B  59
ALA B  87
SER B 228
LEU B  77
LEU B 170
 None
 0.84A 6ew0D-5y6qB:
undetectable		 6ew0D-5y6qB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 LEU B  59
ALA B  87
SER B 228
LEU B  77
LEU B 170
 None
 0.84A 6ew0F-5y6qB:
undetectable		 6ew0F-5y6qB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 LEU B  59
ALA B  87
SER B 228
LEU B  77
LEU B 170
 None
 0.84A 6ew0G-5y6qB:
undetectable		 6ew0G-5y6qB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 LEU B  59
ALA B  87
SER B 228
LEU B  77
LEU B 170
 None
 0.84A 6ew0H-5y6qB:
undetectable		 6ew0H-5y6qB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 LEU B  59
ALA B  87
SER B 228
LEU B  77
LEU B 170
 None
 0.84A 6ew0I-5y6qB:
undetectable		 6ew0I-5y6qB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_D_FOZD403_0
(THYMIDYLATE SYNTHASE)		 5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT
(Methylobacillus
sp.
KY4400) 		5 / 12 PRO C  59
LEU C 101
LEU C  63
ILE C 138
ALA C  93
 None
 1.35A 6qxsD-5y6qC:
undetectable		 6qxsD-5y6qC:
undetectable