SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		5 / 12 PHE A 272
GLY A 211
ALA A 212
SER A 215
LEU A 219
 OLC  A 507 (-4.8A)
None
None
None
None
 1.08A 1fe2A-5y79A:
undetectable		 1fe2A-5y79A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		5 / 12 PHE A 272
GLY A 211
ALA A 212
SER A 215
LEU A 219
 OLC  A 507 (-4.8A)
None
None
None
None
 0.91A 1igxA-5y79A:
undetectable		 1igxA-5y79A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		5 / 12 PHE A 272
GLY A 211
ALA A 212
SER A 215
LEU A 219
 OLC  A 507 (-4.8A)
None
None
None
None
 1.01A 1igxA-5y79A:
undetectable		 1igxA-5y79A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		5 / 12 SER A 178
THR A 182
ASN A 340
ALA A 149
THR A 153
 None
None
3PG  A 516 ( 4.7A)
OLC  A 504 ( 3.9A)
OLC  A 504 (-4.1A)
 1.25A 2nniA-5y79A:
1.8		 2nniA-5y79A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		5 / 12 ILE A 390
PHE A 199
VAL A 364
GLU A 245
THR A 244
 OLC  A 505 ( 3.9A)
None
OLC  A 505 ( 4.2A)
OLC  A 505 (-3.7A)
None
 1.04A 2vn0A-5y79A:
undetectable		 2vn0A-5y79A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		5 / 12 PHE A 272
GLY A 211
ALA A 212
SER A 215
LEU A 219
 OLC  A 507 (-4.8A)
None
None
None
None
 0.98A 3hs6B-5y79A:
undetectable		 3hs6B-5y79A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		3 / 3 TYR A 336
TYR A 289
GLU A 300
 3PG  A 516 ( 4.8A)
None
None
 0.90A 3pfgA-5y79A:
undetectable		 3pfgA-5y79A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		4 / 8 HIS A 337
LEU A 145
THR A 293
HIS A 181
 None
 1.02A 3w6hA-5y79A:
undetectable		 3w6hA-5y79A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		3 / 3 LYS A 128
ARG A 363
VAL A 202
 None
3PG  A 516 (-2.9A)
OLC  A 505 (-4.9A)
 0.89A 4x3uA-5y79A:
undetectable
4x3uB-5y79A:
undetectable		 4x3uA-5y79A:
8.81
4x3uB-5y79A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		4 / 5 GLU A 207
THR A 360
THR A 230
HIS A 224
 None
None
OLC  A 511 ( 4.8A)
None
 1.23A 5axaA-5y79A:
undetectable		 5axaA-5y79A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		4 / 5 GLU A 207
THR A 360
THR A 230
HIS A 224
 None
None
OLC  A 511 ( 4.8A)
None
 1.20A 5axaC-5y79A:
undetectable		 5axaC-5y79A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		4 / 6 THR A 393
TYR A 396
THR A 230
SER A 397
 None
None
OLC  A 511 ( 4.8A)
None
 1.39A 5b6iB-5y79A:
undetectable		 5b6iB-5y79A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		3 / 3 SER A 193
LEU A 325
MET A 133
 None
 0.87A 5ikrB-5y79A:
undetectable		 5ikrB-5y79A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		4 / 7 LEU A 183
ALA A 186
ALA A 187
THR A 251
 None
 0.88A 6a7jA-5y79A:
undetectable		 6a7jA-5y79A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 5y79 PUTATIVE HEXOSE
PHOSPHATE
TRANSLOCATOR
(Galdieria
sulphuraria) 		5 / 11 THR A 387
VAL A 238
THR A 360
ILE A 361
VAL A 364
 OLC  A 505 (-3.8A)
OLC  A 501 ( 4.4A)
None
None
OLC  A 505 ( 4.2A)
 1.06A 6hcoA-5y79A:
undetectable
6hcoB-5y79A:
undetectable		 6hcoA-5y79A:
19.46
6hcoB-5y79A:
19.46