SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y7i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.19A 1a4gA-5y7iA:
undetectable		 1a4gA-5y7iA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.15A 1a4gB-5y7iA:
undetectable		 1a4gB-5y7iA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.11A 1nncA-5y7iA:
undetectable		 1nncA-5y7iA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		4 / 4 ILE A 116
ASP A 181
LEU A 214
ARG A 143
 None
 1.07A 2a7qA-5y7iA:
undetectable		 2a7qA-5y7iA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.16A 2cmlA-5y7iA:
undetectable		 2cmlA-5y7iA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.14A 2cmlB-5y7iA:
undetectable		 2cmlB-5y7iA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.18A 2cmlC-5y7iA:
undetectable		 2cmlC-5y7iA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.18A 2cmlD-5y7iA:
undetectable		 2cmlD-5y7iA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		3 / 3 LYS A  57
LYS A  19
VAL A  52
 None
 0.93A 3brfA-5y7iA:
undetectable		 3brfA-5y7iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		3 / 3 LYS A 187
ARG A  35
ASP A 111
 None
 1.43A 3o7wA-5y7iA:
undetectable		 3o7wA-5y7iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.16A 3sanA-5y7iA:
undetectable		 3sanA-5y7iA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.12A 3sanB-5y7iA:
undetectable		 3sanB-5y7iA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.18A 3ticA-5y7iA:
undetectable		 3ticA-5y7iA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.17A 3ticB-5y7iA:
undetectable		 3ticB-5y7iA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.18A 3ticC-5y7iA:
undetectable		 3ticC-5y7iA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.17A 3ticD-5y7iA:
undetectable		 3ticD-5y7iA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.10A 4cpnA-5y7iA:
undetectable		 4cpnA-5y7iA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.13A 4cpzA-5y7iA:
undetectable		 4cpzA-5y7iA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.10A 4cpzB-5y7iA:
undetectable		 4cpzB-5y7iA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.16A 4cpzD-5y7iA:
undetectable		 4cpzD-5y7iA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.14A 4cpzF-5y7iA:
undetectable		 4cpzF-5y7iA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.19A 4cpzG-5y7iA:
undetectable		 4cpzG-5y7iA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.16A 4cpzH-5y7iA:
undetectable		 4cpzH-5y7iA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		3 / 3 VAL A  27
GLY A  21
LYS A  19
 None
 0.69A 4k50I-5y7iA:
1.3		 4k50I-5y7iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.15A 4mwrA-5y7iA:
undetectable		 4mwrA-5y7iA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 5y7i CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 2
(Oreochromis
mossambicus) 		5 / 12 GLU A  88
ALA A 180
GLU A  87
ARG A  35
ASN A 183
 None
 1.19A 4wa5A-5y7iA:
undetectable		 4wa5A-5y7iA:
12.60