SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y7w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 5y7w NUCLEAR RECEPTOR
COACTIVATOR 1
(Mus
musculus) 		5 / 12 THR A 269
ASP A 267
ILE A 296
PHE A 299
TYR A 297
 None
 1.15A 1oltA-5y7wA:
undetectable		 1oltA-5y7wA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5y7w NUCLEAR RECEPTOR
COACTIVATOR 1
(Mus
musculus) 		4 / 5 ALA A 310
GLY A 360
CYH A 344
LYS A 343
 None
 1.31A 2ylgA-5y7wA:
undetectable		 2ylgA-5y7wA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5y7w NUCLEAR RECEPTOR
COACTIVATOR 1
(Mus
musculus) 		4 / 5 ALA A 310
GLY A 360
CYH A 344
LYS A 343
 None
 1.37A 5jliA-5y7wA:
undetectable		 5jliA-5y7wA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5y7w NUCLEAR RECEPTOR
COACTIVATOR 1
(Mus
musculus) 		4 / 5 ALA A 310
GLY A 360
CYH A 344
LYS A 343
 None
 1.46A 5jt4A-5y7wA:
undetectable		 5jt4A-5y7wA:
21.68