SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EVE_A_E20A2001_1
(ACETYLCHOLINESTERASE)		 5y82 MEMBRANE PROTEIN
INSERTASE YIDC
(Thermotoga
maritima) 		5 / 10 GLY D  71
LEU D  46
PHE D 126
PHE D 116
TYR D  42
 None
 1.39A 1eveA-5y82D:
undetectable		 1eveA-5y82D:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 5y82 MEMBRANE PROTEIN
INSERTASE YIDC
(Thermotoga
maritima) 		4 / 5 PHE D  72
PHE D 178
HIS D 172
VAL D 192
 None
 1.14A 2lh6A-5y82D:
undetectable		 2lh6A-5y82D:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 5y82 MEMBRANE PROTEIN
INSERTASE YIDC
(Thermotoga
maritima) 		4 / 5 LEU D 217
ARG D 199
ALA D 216
ILE D 202
 None
 1.01A 2qhfA-5y82D:
undetectable		 2qhfA-5y82D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 5y82 MEMBRANE PROTEIN
INSERTASE YIDC
(Thermotoga
maritima) 		5 / 12 ASP D 209
LEU D 169
PHE D 193
ILE D 202
PHE D 127
 None
 1.43A 3ko0G-5y82D:
undetectable
3ko0H-5y82D:
undetectable
3ko0I-5y82D:
undetectable
3ko0J-5y82D:
undetectable		 3ko0G-5y82D:
20.62
3ko0H-5y82D:
20.62
3ko0I-5y82D:
20.62
3ko0J-5y82D:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 5y82 MEMBRANE PROTEIN
INSERTASE YIDC
(Thermotoga
maritima) 		5 / 10 VAL D 138
ILE D 130
ILE D 191
PRO D 141
VAL D 140
 None
 1.00A 3nu6A-5y82D:
undetectable		 3nu6A-5y82D:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 5y82 MEMBRANE PROTEIN
INSERTASE YIDC
(Thermotoga
maritima) 		4 / 6 LEU D 170
VAL D 192
PHE D  72
PHE D  65
 None
 1.15A 3soaA-5y82D:
2.0		 3soaA-5y82D:
12.35