SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y86'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BRP_A_RTLA183_0 (RETINOL BINDING PROTEIN)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 12	LEU A 399 ALA A 316 LEU A 336 HIS A 519 PHE A 495	None	1.38A	1brpA-5y86A: undetectable	1brpA-5y86A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TDN_A_LEUA487_0 (L-AMINO ACID OXIDASE)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	4 / 7	ASN A 340 HIS A 333 PHE A 356 ILE A 319	None	1.29A	1tdnA-5y86A: undetectable	1tdnA-5y86A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UWH_B_BAXB1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 12	ALA A 236 LYS A 238 GLU A 253 LEU A 257 LEU A 326 HIS A 333	HRM A 601 (-3.5A) HRM A 601 (-3.3A) HRM A 601 ( 4.6A) None None None	0.78A	1uwhB-5y86A: 20.5	1uwhB-5y86A: 12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UWJ_A_BAXA1723_2 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	4 / 7	ILE A 215 LYS A 238 LEU A 257 ILE A 331	None HRM A 601 (-3.3A) None None	0.80A	1uwjA-5y86A: 6.3	1uwjA-5y86A: 12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UWJ_B_BAXB1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 12	ILE A 215 VAL A 223 ALA A 236 GLU A 253 LEU A 326 HIS A 333	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.6A) None None	1.00A	1uwjB-5y86A: 6.3	1uwjB-5y86A: 12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YI4_A_ADNA306_1 (PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE PIM-1)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 10	PHE A 220 ALA A 236 ILE A 272 ASP A 294 LEU A 342 ILE A 354	HRM A 601 ( 4.1A) HRM A 601 (-3.5A) HRM A 601 ( 4.8A) None None HRM A 601 (-3.7A)	0.84A	1yi4A-5y86A: 24.7	1yi4A-5y86A: 12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	ILE A 215 VAL A 223 LYS A 238 PHE A 288 ASN A 340 LEU A 342 ASP A 355	None HRM A 601 ( 4.9A) HRM A 601 (-3.3A) HRM A 601 (-3.6A) None None HRM A 601 (-4.7A)	0.75A	2eufB-5y86A: 30.1	2eufB-5y86A: 13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	VAL A 223 LYS A 238 PHE A 288 ASP A 294 ASN A 340 LEU A 342 ASP A 355	HRM A 601 ( 4.9A) HRM A 601 (-3.3A) HRM A 601 (-3.6A) None None None HRM A 601 (-4.7A)	0.59A	2eufB-5y86A: 30.1	2eufB-5y86A: 13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J0D_A_ERYA1498_0 (CYTOCHROME P450 3A4)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 12	ILE A 168 ILE A 162 ALA A 175 ARG A 202 GLU A 210	None	1.12A	2j0dA-5y86A: undetectable	2j0dA-5y86A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_A_B49A1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	ILE A 215 VAL A 223 ALA A 236 ILE A 272 PHE A 288 LEU A 290 LEU A 342	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.8A) HRM A 601 (-3.6A) HRM A 601 (-4.6A) None	0.44A	2y7jA-5y86A: 26.1	2y7jA-5y86A: 12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_B_B49B1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 10	ILE A 215 VAL A 223 ALA A 236 ILE A 272 PHE A 288 LEU A 290 ASP A 355	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.8A) HRM A 601 (-3.6A) HRM A 601 (-4.6A) HRM A 601 (-4.7A)	0.70A	2y7jB-5y86A: 26.3	2y7jB-5y86A: 12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_B_B49B1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 10	ILE A 215 VAL A 223 ALA A 236 ILE A 272 PHE A 288 LEU A 290 LEU A 342	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.8A) HRM A 601 (-3.6A) HRM A 601 (-4.6A) None	0.46A	2y7jB-5y86A: 26.3	2y7jB-5y86A: 12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_C_B49C1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 10	ILE A 215 VAL A 223 ALA A 236 ILE A 272 PHE A 288 LEU A 290 LEU A 342	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.8A) HRM A 601 (-3.6A) HRM A 601 (-4.6A) None	0.47A	2y7jC-5y86A: 26.0	2y7jC-5y86A: 12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_D_B49D1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 10	ILE A 215 VAL A 223 ALA A 236 ILE A 272 PHE A 288 LEU A 290 LEU A 342	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.8A) HRM A 601 (-3.6A) HRM A 601 (-4.6A) None	0.50A	2y7jD-5y86A: 26.2	2y7jD-5y86A: 12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	4 / 5	GLN A 305 PHE A 304 LEU A 402 PHE A 315	None	1.26A	3ablC-5y86A: undetectable 3ablJ-5y86A: undetectable	3ablC-5y86A: undetectable 3ablJ-5y86A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BC9_A_ACRA901_1 (ALPHA AMYLASE, CATALYTIC REGION)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	4 / 7	ASP A 506 SER A 508 SER A 387 GLU A 362	None	1.24A	3bc9A-5y86A: undetectable	3bc9A-5y86A: 10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HEC_A_STIA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 12	ALA A 236 LYS A 238 GLU A 253 ILE A 272 LEU A 290	HRM A 601 (-3.5A) HRM A 601 (-3.3A) HRM A 601 ( 4.6A) HRM A 601 ( 4.8A) HRM A 601 (-4.6A)	0.63A	3hecA-5y86A: 21.9	3hecA-5y86A: 13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HEG_A_BAXA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 12	VAL A 223 ALA A 236 LYS A 238 GLU A 253 LEU A 257 ILE A 272	HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 (-3.3A) HRM A 601 ( 4.6A) None HRM A 601 ( 4.8A)	1.03A	3hegA-5y86A: 24.3	3hegA-5y86A: 13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_A_1N1A1000_1 (P38A)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 12	GLY A 216 VAL A 223 ALA A 236 LYS A 238 LEU A 257 ILE A 272	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 (-3.3A) None HRM A 601 ( 4.8A)	0.79A	3ohtA-5y86A: 7.0	3ohtA-5y86A: 11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_B_1N1B1000_1 (P38A)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 12	GLY A 216 VAL A 223 ALA A 236 LYS A 238 ILE A 272	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 (-3.3A) HRM A 601 ( 4.8A)	0.51A	3ohtB-5y86A: 7.4	3ohtB-5y86A: 11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RGF_A_BAXA465_1 (CYCLIN-DEPENDENT KINASE 8)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	VAL A 223 ALA A 236 GLU A 253 LEU A 257 ILE A 272 PHE A 288 LEU A 326	HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.6A) None HRM A 601 ( 4.8A) HRM A 601 (-3.6A) None	0.59A	3rgfA-5y86A: 20.8	3rgfA-5y86A: 11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RGF_A_BAXA465_1 (CYCLIN-DEPENDENT KINASE 8)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	VAL A 223 ALA A 236 LEU A 257 ILE A 272 PHE A 288 LEU A 326 HIS A 333	HRM A 601 ( 4.9A) HRM A 601 (-3.5A) None HRM A 601 ( 4.8A) HRM A 601 (-3.6A) None None	0.63A	3rgfA-5y86A: 20.8	3rgfA-5y86A: 11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TI1_A_B49A299_1 (CYCLIN-DEPENDENT KINASE 2)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 9	ILE A 215 ALA A 236 PHE A 288 ASP A 294 LEU A 342	None HRM A 601 (-3.5A) HRM A 601 (-3.6A) None None	0.71A	3ti1A-5y86A: 27.1	3ti1A-5y86A: 13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WAR_A_NIOA401_1 (CASEIN KINASE II SUBUNIT ALPHA)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 8	VAL A 223 LYS A 238 ILE A 272 PHE A 288 ILE A 354 ASP A 355	HRM A 601 ( 4.9A) HRM A 601 (-3.3A) HRM A 601 ( 4.8A) HRM A 601 (-3.6A) HRM A 601 (-3.7A) HRM A 601 (-4.7A)	0.50A	3warA-5y86A: 21.7	3warA-5y86A: 12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOS_B_0LIB1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	ALA A 236 LYS A 238 GLU A 253 ILE A 272 LEU A 326 HIS A 333 LEU A 342	HRM A 601 (-3.5A) HRM A 601 (-3.3A) HRM A 601 ( 4.6A) HRM A 601 ( 4.8A) None None None	0.74A	3zosB-5y86A: 14.4	3zosB-5y86A: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BKJ_A_STIA1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	VAL A 223 ALA A 236 GLU A 253 ILE A 256 ILE A 272 MET A 286 LEU A 342	HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.6A) None HRM A 601 ( 4.8A) None None	0.91A	4bkjA-5y86A: 19.7	4bkjA-5y86A: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BKJ_B_STIB1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	ALA A 236 GLU A 253 ILE A 256 ILE A 272 MET A 286 LEU A 342 ASP A 355	HRM A 601 (-3.5A) HRM A 601 ( 4.6A) None HRM A 601 ( 4.8A) None None HRM A 601 (-4.7A)	1.16A	4bkjB-5y86A: 19.8	4bkjB-5y86A: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BKJ_B_STIB1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	VAL A 223 ALA A 236 GLU A 253 ILE A 256 ILE A 272 MET A 286 LEU A 342	HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.6A) None HRM A 601 ( 4.8A) None None	0.90A	4bkjB-5y86A: 19.8	4bkjB-5y86A: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I41_A_MIXA500_1 (SERINE/THREONINE-PRO TEIN KINASE PIM-1)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	11 / 12	PHE A 220 VAL A 223 ALA A 236 ILE A 272 ASP A 294 ASP A 335 LYS A 337 ASN A 340 LEU A 342 ILE A 354 ASP A 355	HRM A 601 ( 4.1A) HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.8A) None None PO4 A 602 (-3.5A) None None HRM A 601 (-3.7A) HRM A 601 (-4.7A)	0.74A	4i41A-5y86A: 24.8	4i41A-5y86A: 12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IAA_A_RTZA401_1 (SERINE/THREONINE-PRO TEIN KINASE PIM-1)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	8 / 11	PHE A 220 VAL A 223 ALA A 236 LYS A 238 ASP A 294 LEU A 342 ILE A 354 ASP A 355	HRM A 601 ( 4.1A) HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 (-3.3A) None None HRM A 601 (-3.7A) HRM A 601 (-4.7A)	0.87A	4iaaA-5y86A: 24.5	4iaaA-5y86A: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IAA_A_RTZA401_1 (SERINE/THREONINE-PRO TEIN KINASE PIM-1)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	8 / 11	VAL A 223 ALA A 236 LYS A 238 ASP A 294 GLU A 339 LEU A 342 ILE A 354 ASP A 355	HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 (-3.3A) None None None HRM A 601 (-3.7A) HRM A 601 (-4.7A)	0.76A	4iaaA-5y86A: 24.5	4iaaA-5y86A: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_A_ADNA401_1 (CYCLIN-DEPENDENT KINASE 9)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 8	ILE A 215 VAL A 223 ALA A 236 ASN A 340 LEU A 342	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) None None	0.55A	4ogrA-5y86A: 29.8	4ogrA-5y86A: 11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_A_ADNA401_1 (CYCLIN-DEPENDENT KINASE 9)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 8	VAL A 223 ALA A 236 ASP A 294 ASN A 340 LEU A 342	HRM A 601 ( 4.9A) HRM A 601 (-3.5A) None None None	0.63A	4ogrA-5y86A: 29.8	4ogrA-5y86A: 11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_I_ADNI401_1 (CYCLIN-DEPENDENT KINASE 9)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 9	VAL A 223 ALA A 236 ASP A 294 ASN A 340 LEU A 342 ASP A 355	HRM A 601 ( 4.9A) HRM A 601 (-3.5A) None None None HRM A 601 (-4.7A)	0.74A	4ogrI-5y86A: 23.8	4ogrI-5y86A: 11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTI_A_MI1A1001_1 (SERINE/THREONINE-PRO TEIN KINASE N1)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	7 / 12	GLY A 216 GLY A 218 GLY A 221 VAL A 223 ALA A 236 LYS A 238 LEU A 342	None PO4 A 602 (-3.5A) None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 (-3.3A) None	0.59A	4otiA-5y86A: 14.2	4otiA-5y86A: 14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMS_A_1N1A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 11	ILE A 215 ALA A 236 GLU A 253 LEU A 291 LEU A 342 ASP A 355	None HRM A 601 (-3.5A) HRM A 601 ( 4.6A) None None HRM A 601 (-4.7A)	0.73A	4qmsA-5y86A: 25.4	4qmsA-5y86A: 11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMS_A_1N1A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 11	ILE A 215 ALA A 236 LYS A 238 LEU A 291 LEU A 342 ASP A 355	None HRM A 601 (-3.5A) HRM A 601 (-3.3A) None None HRM A 601 (-4.7A)	0.86A	4qmsA-5y86A: 25.4	4qmsA-5y86A: 11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMZ_A_B49A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 12	ILE A 215 GLY A 216 VAL A 223 ALA A 236 LEU A 291 LEU A 342	None None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) None None	0.59A	4qmzA-5y86A: 25.4	4qmzA-5y86A: 11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RZ7_A_1E8A901_1 (CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 10	ILE A 215 ALA A 236 LYS A 238 ILE A 272 LEU A 290 LEU A 342	None HRM A 601 (-3.5A) HRM A 601 (-3.3A) HRM A 601 ( 4.8A) HRM A 601 (-4.6A) None	0.44A	4rz7A-5y86A: 8.8	4rz7A-5y86A: 6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XV2_B_P06B801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 12	ALA A 236 LYS A 238 LEU A 257 ASP A 355 PHE A 356	HRM A 601 (-3.5A) HRM A 601 (-3.3A) None HRM A 601 (-4.7A) None	0.86A	4xv2B-5y86A: 20.8	4xv2B-5y86A: 13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IZJ_G_AZ1G2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAR-DAR)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 7	GLY A 216 GLY A 218 SER A 219 VAL A 223 LYS A 238	None PO4 A 602 (-3.5A) PO4 A 602 (-2.7A) HRM A 601 ( 4.9A) HRM A 601 (-3.3A)	0.65A	5izjA-5y86A: 24.1	5izjA-5y86A: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J5X_B_AZ1B2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAL-DAR-DAR- DAR-DAR)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 7	GLY A 216 GLY A 218 VAL A 223 LYS A 238 ASP A 355	None PO4 A 602 (-3.5A) HRM A 601 ( 4.9A) HRM A 601 (-3.3A) HRM A 601 (-4.7A)	0.72A	5j5xA-5y86A: 24.8	5j5xA-5y86A: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 12	GLY A 216 VAL A 223 ALA A 236 PHE A 288 ASP A 294 LEU A 342	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 (-3.6A) None None	0.66A	5l2iA-5y86A: 13.1	5l2iA-5y86A: 13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_B_ADNB401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 9	ILE A 215 GLY A 216 VAL A 223 ALA A 236 ILE A 272	None None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.8A)	0.43A	5lw1B-5y86A: 26.4	5lw1B-5y86A: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_E_ADNE401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 10	GLY A 216 VAL A 223 ALA A 236 ILE A 272 LEU A 290	None HRM A 601 ( 4.9A) HRM A 601 (-3.5A) HRM A 601 ( 4.8A) HRM A 601 (-4.6A)	0.46A	5lw1E-5y86A: 26.1	5lw1E-5y86A: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MQT_A_STIA302_1 (DEOXYCYTIDINE KINASE)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 12	ILE A 381 MET A 427 PRO A 478 PHE A 442 CYH A 452	None	1.36A	5mqtA-5y86A: undetectable	5mqtA-5y86A: 12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OWR_A_1N1A401_1 (SERINE/THREONINE-PRO TEIN KINASE 10)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	4 / 8	ALA A 236 GLU A 253 LEU A 342 ASP A 355	HRM A 601 (-3.5A) HRM A 601 ( 4.6A) None HRM A 601 (-4.7A)	0.64A	5owrA-5y86A: 13.6	5owrA-5y86A: 14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_E_CVIE301_0 (REGULATORY PROTEIN TETR)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 12	MET A 274 GLU A 252 LEU A 257 ILE A 254 VAL A 240	None	1.45A	5vlmE-5y86A: undetectable	5vlmE-5y86A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y9M_X_NIOX401_1 (CASEIN KINASE II SUBUNIT ALPHA')	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 8	VAL A 223 LYS A 238 PHE A 288 ILE A 354 ASP A 355	HRM A 601 ( 4.9A) HRM A 601 (-3.3A) HRM A 601 (-3.6A) HRM A 601 (-3.7A) HRM A 601 (-4.7A)	0.31A	5y9mX-5y86A: 22.0	5y9mX-5y86A: 22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YF9_B_NIOB401_1 (CASEIN KINASE II SUBUNIT ALPHA')	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 7	VAL A 223 LYS A 238 PHE A 288 ILE A 354 ASP A 355	HRM A 601 ( 4.9A) HRM A 601 (-3.3A) HRM A 601 (-3.6A) HRM A 601 (-3.7A) HRM A 601 (-4.7A)	0.51A	5yf9B-5y86A: 27.7	5yf9B-5y86A: 22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YF9_X_NIOX401_1 (CASEIN KINASE II SUBUNIT ALPHA')	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 9	VAL A 223 LYS A 238 ILE A 272 PHE A 288 ILE A 354 ASP A 355	HRM A 601 ( 4.9A) HRM A 601 (-3.3A) HRM A 601 ( 4.8A) HRM A 601 (-3.6A) HRM A 601 (-3.7A) HRM A 601 (-4.7A)	0.50A	5yf9X-5y86A: 19.1	5yf9X-5y86A: 22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YWM_X_NIOX403_0 (CASEIN KINASE II SUBUNIT ALPHA')	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	6 / 7	VAL A 223 LYS A 238 ILE A 272 PHE A 288 ILE A 354 ASP A 355	HRM A 601 ( 4.9A) HRM A 601 (-3.3A) HRM A 601 ( 4.8A) HRM A 601 (-3.6A) HRM A 601 (-3.7A) HRM A 601 (-4.7A)	0.37A	5ywmX-5y86A: 27.4	5ywmX-5y86A: 22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6APH_A_ADNA501_1 (ADENOSYLHOMOCYSTEINA SE)	5y86	DUAL SPECIFICITY TYROSINE-PHOSPHORYLA TION-REGULATED KINASE 3 (Homo sapiens)	5 / 12	LEU A 257 GLU A 253 ASP A 355 LEU A 326 PHE A 288	None HRM A 601 ( 4.6A) HRM A 601 (-4.7A) None HRM A 601 (-3.6A)	1.45A	6aphA-5y86A: undetectable	6aphA-5y86A: 9.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1BRP_A_RTLA183_0","RETINOL BINDING PROTEIN","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"LEU A 399;ALA A 316;LEU A 336;HIS A 519;PHE A 495","None","1.38A","1brpA-5y86A:undetectable","1brpA-5y86A:undetectable"],["1TDN_A_LEUA487_0","L-AMINO ACID OXIDASE","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",4,"ASN A 340;HIS A 333;PHE A 356;ILE A 319","None","1.29A","1tdnA-5y86A:undetectable","1tdnA-5y86A:undetectable"],["1UWH_B_BAXB1723_1","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"ALA A 236;LYS A 238;GLU A 253;LEU A 257;LEU A 326;HIS A 333","HRM A 601 (-3.5A);HRM A 601 (-3.3A);HRM A 601 ( 4.6A);None;None;None","0.78A","1uwhB-5y86A:20.5","1uwhB-5y86A:12.23"],["1UWJ_A_BAXA1723_2","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",4,"ILE A 215;LYS A 238;LEU A 257;ILE A 331","None;HRM A 601 (-3.3A);None;None","0.80A","1uwjA-5y86A:6.3","1uwjA-5y86A:12.23"],["1UWJ_B_BAXB1723_1","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"ILE A 215;VAL A 223;ALA A 236;GLU A 253;LEU A 326;HIS A 333","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.6A);None;None","1.00A","1uwjB-5y86A:6.3","1uwjB-5y86A:12.23"],["1YI4_A_ADNA306_1","PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE PIM-1","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"PHE A 220;ALA A 236;ILE A 272;ASP A 294;LEU A 342;ILE A 354","HRM A 601 ( 4.1A);HRM A 601 (-3.5A);HRM A 601 ( 4.8A);None;None;HRM A 601 (-3.7A)","0.84A","1yi4A-5y86A:24.7","1yi4A-5y86A:12.45"],["2EUF_B_LQQB401_1","CELL DIVISION PROTEIN KINASE 6","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"ILE A 215;VAL A 223;LYS A 238;PHE A 288;ASN A 340;LEU A 342;ASP A 355","None;HRM A 601 ( 4.9A);HRM A 601 (-3.3A);HRM A 601 (-3.6A);None;None;HRM A 601 (-4.7A)","0.75A","2eufB-5y86A:30.1","2eufB-5y86A:13.53"],["2EUF_B_LQQB401_1","CELL DIVISION PROTEIN KINASE 6","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"VAL A 223;LYS A 238;PHE A 288;ASP A 294;ASN A 340;LEU A 342;ASP A 355","HRM A 601 ( 4.9A);HRM A 601 (-3.3A);HRM A 601 (-3.6A);None;None;None;HRM A 601 (-4.7A)","0.59A","2eufB-5y86A:30.1","2eufB-5y86A:13.53"],["2J0D_A_ERYA1498_0","CYTOCHROME P450 3A4","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"ILE A 168;ILE A 162;ALA A 175;ARG A 202;GLU A 210","None","1.12A","2j0dA-5y86A:undetectable","2j0dA-5y86A:undetectable"],["2Y7J_A_B49A1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"ILE A 215;VAL A 223;ALA A 236;ILE A 272;PHE A 288;LEU A 290;LEU A 342","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.8A);HRM A 601 (-3.6A);HRM A 601 (-4.6A);None","0.44A","2y7jA-5y86A:26.1","2y7jA-5y86A:12.88"],["2Y7J_B_B49B1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"ILE A 215;VAL A 223;ALA A 236;ILE A 272;PHE A 288;LEU A 290;ASP A 355","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.8A);HRM A 601 (-3.6A);HRM A 601 (-4.6A);HRM A 601 (-4.7A)","0.70A","2y7jB-5y86A:26.3","2y7jB-5y86A:12.88"],["2Y7J_B_B49B1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"ILE A 215;VAL A 223;ALA A 236;ILE A 272;PHE A 288;LEU A 290;LEU A 342","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.8A);HRM A 601 (-3.6A);HRM A 601 (-4.6A);None","0.46A","2y7jB-5y86A:26.3","2y7jB-5y86A:12.88"],["2Y7J_C_B49C1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"ILE A 215;VAL A 223;ALA A 236;ILE A 272;PHE A 288;LEU A 290;LEU A 342","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.8A);HRM A 601 (-3.6A);HRM A 601 (-4.6A);None","0.47A","2y7jC-5y86A:26.0","2y7jC-5y86A:12.88"],["2Y7J_D_B49D1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"ILE A 215;VAL A 223;ALA A 236;ILE A 272;PHE A 288;LEU A 290;LEU A 342","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.8A);HRM A 601 (-3.6A);HRM A 601 (-4.6A);None","0.50A","2y7jD-5y86A:26.2","2y7jD-5y86A:12.88"],["3ABL_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",4,"GLN A 305;PHE A 304;LEU A 402;PHE A 315","None","1.26A","3ablC-5y86A:undetectable;3ablJ-5y86A:undetectable","3ablC-5y86A:undetectable;3ablJ-5y86A:undetectable"],["3BC9_A_ACRA901_1","ALPHA AMYLASE, CATALYTIC REGION","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",4,"ASP A 506;SER A 508;SER A 387;GLU A 362","None","1.24A","3bc9A-5y86A:undetectable","3bc9A-5y86A:10.17"],["3HEC_A_STIA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"ALA A 236;LYS A 238;GLU A 253;ILE A 272;LEU A 290","HRM A 601 (-3.5A);HRM A 601 (-3.3A);HRM A 601 ( 4.6A);HRM A 601 ( 4.8A);HRM A 601 (-4.6A)","0.63A","3hecA-5y86A:21.9","3hecA-5y86A:13.49"],["3HEG_A_BAXA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"VAL A 223;ALA A 236;LYS A 238;GLU A 253;LEU A 257;ILE A 272","HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 (-3.3A);HRM A 601 ( 4.6A);None;HRM A 601 ( 4.8A)","1.03A","3hegA-5y86A:24.3","3hegA-5y86A:13.49"],["3OHT_A_1N1A1000_1","P38A","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"GLY A 216;VAL A 223;ALA A 236;LYS A 238;LEU A 257;ILE A 272","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 (-3.3A);None;HRM A 601 ( 4.8A)","0.79A","3ohtA-5y86A:7.0","3ohtA-5y86A:11.43"],["3OHT_B_1N1B1000_1","P38A","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"GLY A 216;VAL A 223;ALA A 236;LYS A 238;ILE A 272","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 (-3.3A);HRM A 601 ( 4.8A)","0.51A","3ohtB-5y86A:7.4","3ohtB-5y86A:11.43"],["3RGF_A_BAXA465_1","CYCLIN-DEPENDENT KINASE 8","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"VAL A 223;ALA A 236;GLU A 253;LEU A 257;ILE A 272;PHE A 288;LEU A 326","HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.6A);None;HRM A 601 ( 4.8A);HRM A 601 (-3.6A);None","0.59A","3rgfA-5y86A:20.8","3rgfA-5y86A:11.41"],["3RGF_A_BAXA465_1","CYCLIN-DEPENDENT KINASE 8","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"VAL A 223;ALA A 236;LEU A 257;ILE A 272;PHE A 288;LEU A 326;HIS A 333","HRM A 601 ( 4.9A);HRM A 601 (-3.5A);None;HRM A 601 ( 4.8A);HRM A 601 (-3.6A);None;None","0.63A","3rgfA-5y86A:20.8","3rgfA-5y86A:11.41"],["3TI1_A_B49A299_1","CYCLIN-DEPENDENT KINASE 2","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"ILE A 215;ALA A 236;PHE A 288;ASP A 294;LEU A 342","None;HRM A 601 (-3.5A);HRM A 601 (-3.6A);None;None","0.71A","3ti1A-5y86A:27.1","3ti1A-5y86A:13.09"],["3WAR_A_NIOA401_1","CASEIN KINASE II SUBUNIT ALPHA","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"VAL A 223;LYS A 238;ILE A 272;PHE A 288;ILE A 354;ASP A 355","HRM A 601 ( 4.9A);HRM A 601 (-3.3A);HRM A 601 ( 4.8A);HRM A 601 (-3.6A);HRM A 601 (-3.7A);HRM A 601 (-4.7A)","0.50A","3warA-5y86A:21.7","3warA-5y86A:12.84"],["3ZOS_B_0LIB1000_1","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"ALA A 236;LYS A 238;GLU A 253;ILE A 272;LEU A 326;HIS A 333;LEU A 342","HRM A 601 (-3.5A);HRM A 601 (-3.3A);HRM A 601 ( 4.6A);HRM A 601 ( 4.8A);None;None;None","0.74A","3zosB-5y86A:14.4","3zosB-5y86A:12.90"],["4BKJ_A_STIA1000_1","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"VAL A 223;ALA A 236;GLU A 253;ILE A 256;ILE A 272;MET A 286;LEU A 342","HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.6A);None;HRM A 601 ( 4.8A);None;None","0.91A","4bkjA-5y86A:19.7","4bkjA-5y86A:12.90"],["4BKJ_B_STIB1000_1","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"ALA A 236;GLU A 253;ILE A 256;ILE A 272;MET A 286;LEU A 342;ASP A 355","HRM A 601 (-3.5A);HRM A 601 ( 4.6A);None;HRM A 601 ( 4.8A);None;None;HRM A 601 (-4.7A)","1.16A","4bkjB-5y86A:19.8","4bkjB-5y86A:12.90"],["4BKJ_B_STIB1000_1","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"VAL A 223;ALA A 236;GLU A 253;ILE A 256;ILE A 272;MET A 286;LEU A 342","HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.6A);None;HRM A 601 ( 4.8A);None;None","0.90A","4bkjB-5y86A:19.8","4bkjB-5y86A:12.90"],["4I41_A_MIXA500_1","SERINE\/THREONINE-PROTEIN KINASE PIM-1","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",11,"PHE A 220;VAL A 223;ALA A 236;ILE A 272;ASP A 294;ASP A 335;LYS A 337;ASN A 340;LEU A 342;ILE A 354;ASP A 355","HRM A 601 ( 4.1A);HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.8A);None;None;PO4 A 602 (-3.5A);None;None;HRM A 601 (-3.7A);HRM A 601 (-4.7A)","0.74A","4i41A-5y86A:24.8","4i41A-5y86A:12.59"],["4IAA_A_RTZA401_1","SERINE\/THREONINE-PROTEIN KINASE PIM-1","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",8,"PHE A 220;VAL A 223;ALA A 236;LYS A 238;ASP A 294;LEU A 342;ILE A 354;ASP A 355","HRM A 601 ( 4.1A);HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 (-3.3A);None;None;HRM A 601 (-3.7A);HRM A 601 (-4.7A)","0.87A","4iaaA-5y86A:24.5","4iaaA-5y86A:13.07"],["4IAA_A_RTZA401_1","SERINE\/THREONINE-PROTEIN KINASE PIM-1","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",8,"VAL A 223;ALA A 236;LYS A 238;ASP A 294;GLU A 339;LEU A 342;ILE A 354;ASP A 355","HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 (-3.3A);None;None;None;HRM A 601 (-3.7A);HRM A 601 (-4.7A)","0.76A","4iaaA-5y86A:24.5","4iaaA-5y86A:13.07"],["4OGR_A_ADNA401_1","CYCLIN-DEPENDENT KINASE 9","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"ILE A 215;VAL A 223;ALA A 236;ASN A 340;LEU A 342","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);None;None","0.55A","4ogrA-5y86A:29.8","4ogrA-5y86A:11.66"],["4OGR_A_ADNA401_1","CYCLIN-DEPENDENT KINASE 9","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"VAL A 223;ALA A 236;ASP A 294;ASN A 340;LEU A 342","HRM A 601 ( 4.9A);HRM A 601 (-3.5A);None;None;None","0.63A","4ogrA-5y86A:29.8","4ogrA-5y86A:11.66"],["4OGR_I_ADNI401_1","CYCLIN-DEPENDENT KINASE 9","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"VAL A 223;ALA A 236;ASP A 294;ASN A 340;LEU A 342;ASP A 355","HRM A 601 ( 4.9A);HRM A 601 (-3.5A);None;None;None;HRM A 601 (-4.7A)","0.74A","4ogrI-5y86A:23.8","4ogrI-5y86A:11.66"],["4OTI_A_MI1A1001_1","SERINE\/THREONINE-PROTEIN KINASE N1","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",7,"GLY A 216;GLY A 218;GLY A 221;VAL A 223;ALA A 236;LYS A 238;LEU A 342","None;PO4 A 602 (-3.5A);None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 (-3.3A);None","0.59A","4otiA-5y86A:14.2","4otiA-5y86A:14.54"],["4QMS_A_1N1A401_1","SERINE\/THREONINE-PROTEIN KINASE 24","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"ILE A 215;ALA A 236;GLU A 253;LEU A 291;LEU A 342;ASP A 355","None;HRM A 601 (-3.5A);HRM A 601 ( 4.6A);None;None;HRM A 601 (-4.7A)","0.73A","4qmsA-5y86A:25.4","4qmsA-5y86A:11.88"],["4QMS_A_1N1A401_1","SERINE\/THREONINE-PROTEIN KINASE 24","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"ILE A 215;ALA A 236;LYS A 238;LEU A 291;LEU A 342;ASP A 355","None;HRM A 601 (-3.5A);HRM A 601 (-3.3A);None;None;HRM A 601 (-4.7A)","0.86A","4qmsA-5y86A:25.4","4qmsA-5y86A:11.88"],["4QMZ_A_B49A401_1","SERINE\/THREONINE-PROTEIN KINASE 24","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"ILE A 215;GLY A 216;VAL A 223;ALA A 236;LEU A 291;LEU A 342","None;None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);None;None","0.59A","4qmzA-5y86A:25.4","4qmzA-5y86A:11.88"],["4RZ7_A_1E8A901_1","CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"ILE A 215;ALA A 236;LYS A 238;ILE A 272;LEU A 290;LEU A 342","None;HRM A 601 (-3.5A);HRM A 601 (-3.3A);HRM A 601 ( 4.8A);HRM A 601 (-4.6A);None","0.44A","4rz7A-5y86A:8.8","4rz7A-5y86A:6.98"],["4XV2_B_P06B801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"ALA A 236;LYS A 238;LEU A 257;ASP A 355;PHE A 356","HRM A 601 (-3.5A);HRM A 601 (-3.3A);None;HRM A 601 (-4.7A);None","0.86A","4xv2B-5y86A:20.8","4xv2B-5y86A:13.01"],["5IZJ_G_AZ1G2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAR-DAR","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"GLY A 216;GLY A 218;SER A 219;VAL A 223;LYS A 238","None;PO4 A 602 (-3.5A);PO4 A 602 (-2.7A);HRM A 601 ( 4.9A);HRM A 601 (-3.3A)","0.65A","5izjA-5y86A:24.1","5izjA-5y86A:12.46"],["5J5X_B_AZ1B2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAL-DAR-DAR-DAR-DAR","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"GLY A 216;GLY A 218;VAL A 223;LYS A 238;ASP A 355","None;PO4 A 602 (-3.5A);HRM A 601 ( 4.9A);HRM A 601 (-3.3A);HRM A 601 (-4.7A)","0.72A","5j5xA-5y86A:24.8","5j5xA-5y86A:12.46"],["5L2I_A_LQQA900_1","CYCLIN-DEPENDENT KINASE 6","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"GLY A 216;VAL A 223;ALA A 236;PHE A 288;ASP A 294;LEU A 342","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 (-3.6A);None;None","0.66A","5l2iA-5y86A:13.1","5l2iA-5y86A:13.07"],["5LW1_B_ADNB401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"ILE A 215;GLY A 216;VAL A 223;ALA A 236;ILE A 272","None;None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.8A)","0.43A","5lw1B-5y86A:26.4","5lw1B-5y86A:19.19"],["5LW1_E_ADNE401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"GLY A 216;VAL A 223;ALA A 236;ILE A 272;LEU A 290","None;HRM A 601 ( 4.9A);HRM A 601 (-3.5A);HRM A 601 ( 4.8A);HRM A 601 (-4.6A)","0.46A","5lw1E-5y86A:26.1","5lw1E-5y86A:19.19"],["5MQT_A_STIA302_1","DEOXYCYTIDINE KINASE","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"ILE A 381;MET A 427;PRO A 478;PHE A 442;CYH A 452","None","1.36A","5mqtA-5y86A:undetectable","5mqtA-5y86A:12.04"],["5OWR_A_1N1A401_1","SERINE\/THREONINE-PROTEIN KINASE 10","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",4,"ALA A 236;GLU A 253;LEU A 342;ASP A 355","HRM A 601 (-3.5A);HRM A 601 ( 4.6A);None;HRM A 601 (-4.7A)","0.64A","5owrA-5y86A:13.6","5owrA-5y86A:14.38"],["5VLM_E_CVIE301_0","REGULATORY PROTEIN TETR","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"MET A 274;GLU A 252;LEU A 257;ILE A 254;VAL A 240","None","1.45A","5vlmE-5y86A:undetectable","5vlmE-5y86A:undetectable"],["5Y9M_X_NIOX401_1","CASEIN KINASE II SUBUNIT ALPHA'","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"VAL A 223;LYS A 238;PHE A 288;ILE A 354;ASP A 355","HRM A 601 ( 4.9A);HRM A 601 (-3.3A);HRM A 601 (-3.6A);HRM A 601 (-3.7A);HRM A 601 (-4.7A)","0.31A","5y9mX-5y86A:22.0","5y9mX-5y86A:22.00"],["5YF9_B_NIOB401_1","CASEIN KINASE II SUBUNIT ALPHA'","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"VAL A 223;LYS A 238;PHE A 288;ILE A 354;ASP A 355","HRM A 601 ( 4.9A);HRM A 601 (-3.3A);HRM A 601 (-3.6A);HRM A 601 (-3.7A);HRM A 601 (-4.7A)","0.51A","5yf9B-5y86A:27.7","5yf9B-5y86A:22.00"],["5YF9_X_NIOX401_1","CASEIN KINASE II SUBUNIT ALPHA'","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"VAL A 223;LYS A 238;ILE A 272;PHE A 288;ILE A 354;ASP A 355","HRM A 601 ( 4.9A);HRM A 601 (-3.3A);HRM A 601 ( 4.8A);HRM A 601 (-3.6A);HRM A 601 (-3.7A);HRM A 601 (-4.7A)","0.50A","5yf9X-5y86A:19.1","5yf9X-5y86A:22.00"],["5YWM_X_NIOX403_0","CASEIN KINASE II SUBUNIT ALPHA'","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",6,"VAL A 223;LYS A 238;ILE A 272;PHE A 288;ILE A 354;ASP A 355","HRM A 601 ( 4.9A);HRM A 601 (-3.3A);HRM A 601 ( 4.8A);HRM A 601 (-3.6A);HRM A 601 (-3.7A);HRM A 601 (-4.7A)","0.37A","5ywmX-5y86A:27.4","5ywmX-5y86A:22.00"],["6APH_A_ADNA501_1","ADENOSYLHOMOCYSTEINASE","5y86","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3","Homo sapiens",5,"LEU A 257;GLU A 253;ASP A 355;LEU A 326;PHE A 288","None;HRM A 601 ( 4.6A);HRM A 601 (-4.7A);None;HRM A 601 (-3.6A)","1.45A","6aphA-5y86A:undetectable","6aphA-5y86A:9.86"]]