SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5y88

(;
) 		3 / 3 VAL U 691
LYS U 699
HIS T 129
 None
 0.60A 3elzA-5y88U:
undetectable		 3elzA-5y88U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 5y88 -
(-) 		4 / 8 TYR U 640
ASP U 707
VAL U 682
LEU U 703
 None
 0.86A 4f8hA-5y88U:
2.3
4f8hB-5y88U:
2.4		 4f8hA-5y88U:
undetectable
4f8hB-5y88U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 5y88 -
(-) 		4 / 8 TYR U 640
ASP U 707
VAL U 682
LEU U 703
 None
 0.98A 4f8hB-5y88U:
2.4
4f8hC-5y88U:
2.4		 4f8hB-5y88U:
undetectable
4f8hC-5y88U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 5y88 -
(-) 		4 / 8 TYR U 640
ASP U 707
VAL U 682
LEU U 703
 None
 0.89A 4f8hC-5y88U:
2.5
4f8hD-5y88U:
2.4		 4f8hC-5y88U:
undetectable
4f8hD-5y88U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 5y88 -
(-) 		4 / 8 TYR U 640
ASP U 707
VAL U 682
LEU U 703
 None
 0.89A 4f8hD-5y88U:
2.4
4f8hE-5y88U:
2.4		 4f8hD-5y88U:
undetectable
4f8hE-5y88U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 5y88 -
(-) 		4 / 8 VAL U 682
LEU U 703
TYR U 640
ASP U 707
 None
 0.91A 4f8hA-5y88U:
2.3
4f8hE-5y88U:
2.5		 4f8hA-5y88U:
undetectable
4f8hE-5y88U:
undetectable