SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y96'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 5y96 RECEPTOR-LIKE
PROTEIN KINASE
ANXUR1
(Arabidopsis
thaliana) 		4 / 6 PRO B 352
PHE B 190
LEU B 189
ILE B 269
 None
 1.08A 1sbrA-5y96B:
undetectable
1sbrB-5y96B:
undetectable		 1sbrA-5y96B:
17.44
1sbrB-5y96B:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5y96 RECEPTOR-LIKE
PROTEIN KINASE
ANXUR1
(Arabidopsis
thaliana) 		5 / 12 LEU B 389
ASN B 390
LEU B 252
GLN B 315
MET B 374
 None
 1.45A 1ya3A-5y96B:
undetectable		 1ya3A-5y96B:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5y96 RECEPTOR-LIKE
PROTEIN KINASE
ANXUR1
(Arabidopsis
thaliana) 		5 / 12 LEU B 389
ASN B 390
LEU B 252
GLN B 315
MET B 374
 None
 1.46A 2aa5B-5y96B:
undetectable		 2aa5B-5y96B:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5y96 RECEPTOR-LIKE
PROTEIN KINASE
ANXUR1
(Arabidopsis
thaliana) 		5 / 12 LEU B 389
ASN B 390
LEU B 252
GLN B 315
MET B 374
 None
 1.40A 2oaxA-5y96B:
undetectable		 2oaxA-5y96B:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 5y96 RECEPTOR-LIKE
PROTEIN KINASE
ANXUR1
(Arabidopsis
thaliana) 		5 / 12 LEU B 153
LEU B 129
VAL B 122
ILE B 181
GLU B 182
 None
 1.18A 2weyA-5y96B:
undetectable		 2weyA-5y96B:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 5y96 RECEPTOR-LIKE
PROTEIN KINASE
ANXUR1
(Arabidopsis
thaliana) 		4 / 6 ARG B 102
ASP B 228
ILE B 223
GLU B 393
 None
 1.29A 2ya7C-5y96B:
undetectable		 2ya7C-5y96B:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5y96 RECEPTOR-LIKE
PROTEIN KINASE
ANXUR1
(Arabidopsis
thaliana) 		5 / 12 GLY B 180
LEU B 103
TYR B  89
ILE B 163
LEU B 161
 None
 0.95A 3gwvA-5y96B:
undetectable		 3gwvA-5y96B:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5y96 RECEPTOR-LIKE
PROTEIN KINASE
ANXUR1
(Arabidopsis
thaliana) 		4 / 7 LEU B 153
LEU B 129
ASN B 125
THR B 166
 None
 1.02A 3lm8B-5y96B:
undetectable
3lm8D-5y96B:
undetectable		 3lm8B-5y96B:
20.75
3lm8D-5y96B:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 5y96 RECEPTOR-LIKE
PROTEIN KINASE
ANXUR1
(Arabidopsis
thaliana) 		4 / 8 LEU B 210
GLU B 150
LEU B 100
ARG B 215
 None
 1.15A 5dxeA-5y96B:
undetectable		 5dxeA-5y96B:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5y96 RECEPTOR-LIKE
PROTEIN KINASE
ANXUR1
(Arabidopsis
thaliana) 		4 / 8 LEU B 210
GLU B 150
LEU B 100
ARG B 215
 None
 1.19A 6cbzA-5y96B:
undetectable		 6cbzA-5y96B:
24.75