SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 5y9c MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
9) 		4 / 8 ASP A 202
TYR A 234
ARG A 251
THR A 155
 None
 1.44A 1ceaA-5y9cA:
undetectable
1ceaB-5y9cA:
undetectable		 1ceaA-5y9cA:
13.68
1ceaB-5y9cA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY5_A_ACTA600_0
(RIBONUCLEASE A)		 5y9c MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
9) 		4 / 4 HIS A 365
VAL A 118
ASN A 341
THR A 340
 None
 1.47A 1dy5A-5y9cA:
undetectable		 1dy5A-5y9cA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 5y9c MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
9) 		4 / 8 PHE A  74
LEU A  42
GLY A 109
ASP A 370
 None
 0.88A 1rmtC-5y9cA:
undetectable		 1rmtC-5y9cA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5y9c MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
9) 		5 / 11 PHE A 373
PHE A 375
ILE A 160
GLY A 161
LEU A  78
 None
 0.98A 1z11A-5y9cA:
undetectable		 1z11A-5y9cA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 5y9c MAJOR CAPSID PROTEIN
L1
HEAVY CHAIN OF FAB
FRAGMENT OF ANTIBODY
A12A3
(Alphapapillomavi
rus
9;
Mus
musculus) 		3 / 3 ARG A 135
GLU H  54
TYR H  33
 None
 0.95A 3k37B-5y9cA:
undetectable		 3k37B-5y9cA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 5y9c MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
9) 		4 / 7 PHE A 127
GLY A 265
PHE A 261
PHE A 292
 None
 1.02A 3ko0D-5y9cA:
undetectable
3ko0E-5y9cA:
undetectable		 3ko0D-5y9cA:
13.03
3ko0E-5y9cA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5y9c MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
9) 		4 / 5 TYR A  36
GLN A 372
GLY A  38
SER A  39
 None
 0.84A 4fu8A-5y9cA:
undetectable		 4fu8A-5y9cA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 5y9c MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
9) 		3 / 3 CYH A 229
LYS A 230
HIS A 169
 None
 1.16A 5js5A-5y9cA:
undetectable		 5js5A-5y9cA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5y9c HEAVY CHAIN OF FAB
FRAGMENT OF ANTIBODY
A12A3
(Mus
musculus) 		4 / 5 GLU H 154
PHE H 152
HIS H 205
THR H 117
 None
 1.10A 6b58A-5y9cH:
undetectable		 6b58A-5y9cH:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5y9c MAJOR CAPSID PROTEIN
L1
(Alphapapillomavi
rus
9) 		4 / 8 TYR A  35
THR A  89
TRP A 101
LEU A  99
 None
 1.11A 6cnjD-5y9cA:
undetectable
6cnjE-5y9cA:
undetectable		 6cnjD-5y9cA:
10.88
6cnjE-5y9cA:
10.68