SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.13A 1c8lA-5y9dA:
undetectable		 1c8lA-5y9dA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.07A 1gfzA-5y9dA:
undetectable		 1gfzA-5y9dA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 ARG A 617
THR A 624
VAL A 620
 None
 0.90A 1hxbA-5y9dA:
undetectable		 1hxbA-5y9dA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.04A 1l5qA-5y9dA:
undetectable		 1l5qA-5y9dA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.04A 1l5qB-5y9dA:
undetectable		 1l5qB-5y9dA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.00A 1l7xA-5y9dA:
undetectable		 1l7xA-5y9dA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.03A 1l7xB-5y9dA:
undetectable		 1l7xB-5y9dA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 ARG A 242
ILE A 412
TRP A 437
 None
 1.19A 1m8eB-5y9dA:
undetectable		 1m8eB-5y9dA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.10A 1v54A-5y9dA:
2.6
1v54C-5y9dA:
undetectable		 1v54A-5y9dA:
undetectable
1v54C-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.09A 1v54N-5y9dA:
2.8
1v54P-5y9dA:
2.2		 1v54N-5y9dA:
undetectable
1v54P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 1v55A-5y9dA:
1.5
1v55C-5y9dA:
2.2		 1v55A-5y9dA:
undetectable
1v55C-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 1v55C-5y9dA:
2.2
1v55N-5y9dA:
2.0
1v55P-5y9dA:
2.2		 1v55C-5y9dA:
undetectable
1v55N-5y9dA:
undetectable
1v55P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.10A 2dyrA-5y9dA:
2.8
2dyrC-5y9dA:
undetectable		 2dyrA-5y9dA:
undetectable
2dyrC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.09A 2dyrN-5y9dA:
3.0
2dyrP-5y9dA:
undetectable		 2dyrN-5y9dA:
undetectable
2dyrP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 2dysA-5y9dA:
3.0
2dysC-5y9dA:
2.2		 2dysA-5y9dA:
undetectable
2dysC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 2dysN-5y9dA:
1.0
2dysP-5y9dA:
2.2		 2dysN-5y9dA:
undetectable
2dysP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 2eijA-5y9dA:
2.9
2eijC-5y9dA:
2.2		 2eijA-5y9dA:
undetectable
2eijC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 2eijN-5y9dA:
1.9
2eijP-5y9dA:
2.1		 2eijN-5y9dA:
undetectable
2eijP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 2eikA-5y9dA:
3.0
2eikC-5y9dA:
undetectable		 2eikA-5y9dA:
undetectable
2eikC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 2eikN-5y9dA:
3.0
2eikP-5y9dA:
2.2		 2eikN-5y9dA:
undetectable
2eikP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 2eilA-5y9dA:
3.0
2eilC-5y9dA:
undetectable		 2eilA-5y9dA:
undetectable
2eilC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 2eilN-5y9dA:
0.7
2eilP-5y9dA:
2.2		 2eilN-5y9dA:
undetectable
2eilP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.15A 2eimA-5y9dA:
0.5
2eimC-5y9dA:
2.2		 2eimA-5y9dA:
undetectable
2eimC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 2eimN-5y9dA:
0.2
2eimP-5y9dA:
2.2		 2eimN-5y9dA:
undetectable
2eimP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 2einA-5y9dA:
undetectable
2einC-5y9dA:
2.2		 2einA-5y9dA:
undetectable
2einC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.16A 2einN-5y9dA:
3.0
2einP-5y9dA:
2.2		 2einN-5y9dA:
undetectable
2einP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 ARG A 617
THR A 624
VAL A 620
 None
 0.88A 2qakA-5y9dA:
undetectable		 2qakA-5y9dA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 VAL A 609
ASP A 610
GLU A 585
 None
 0.44A 2qeuA-5y9dA:
undetectable		 2qeuA-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 VAL A 609
ASP A 610
GLU A 585
 None
 0.45A 2qeuC-5y9dA:
2.3		 2qeuC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VTB_B_ACTB1500_0
(CRYPTOCHROME DASH)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 4 ARG A 305
PHE A 632
VAL A  56
ASP A 101
 None
 1.30A 2vtbB-5y9dA:
0.0		 2vtbB-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1436_1
(ORF12)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 9 HIS A 548
VAL A 478
ILE A 514
GLY A 457
ALA A 395
 None
 1.29A 2xh9B-5y9dA:
undetectable		 2xh9B-5y9dA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 2y69A-5y9dA:
3.0
2y69C-5y9dA:
2.2		 2y69A-5y9dA:
undetectable
2y69C-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 2y69C-5y9dA:
2.2
2y69N-5y9dA:
3.0
2y69P-5y9dA:
2.2		 2y69C-5y9dA:
undetectable
2y69N-5y9dA:
undetectable
2y69P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 2zxwA-5y9dA:
2.8
2zxwC-5y9dA:
2.2		 2zxwA-5y9dA:
undetectable
2zxwC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 2zxwN-5y9dA:
2.8
2zxwP-5y9dA:
2.1		 2zxwN-5y9dA:
undetectable
2zxwP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 3abkA-5y9dA:
3.5
3abkC-5y9dA:
2.2		 3abkA-5y9dA:
undetectable
3abkC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 3abkN-5y9dA:
3.0
3abkP-5y9dA:
undetectable		 3abkN-5y9dA:
undetectable
3abkP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 3ablA-5y9dA:
2.9
3ablC-5y9dA:
2.2
3ablP-5y9dA:
2.2		 3ablA-5y9dA:
undetectable
3ablC-5y9dA:
undetectable
3ablP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 3ablC-5y9dA:
2.2
3ablN-5y9dA:
1.1
3ablP-5y9dA:
2.2		 3ablC-5y9dA:
undetectable
3ablN-5y9dA:
undetectable
3ablP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 3abmA-5y9dA:
3.0
3abmC-5y9dA:
2.2
3abmP-5y9dA:
2.2		 3abmA-5y9dA:
undetectable
3abmC-5y9dA:
undetectable
3abmP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 3abmN-5y9dA:
1.9
3abmP-5y9dA:
undetectable		 3abmN-5y9dA:
undetectable
3abmP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 3ag1A-5y9dA:
2.8
3ag1C-5y9dA:
2.2		 3ag1A-5y9dA:
undetectable
3ag1C-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.08A 3ag1N-5y9dA:
0.2
3ag1P-5y9dA:
2.1		 3ag1N-5y9dA:
undetectable
3ag1P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.14A 3ag2A-5y9dA:
1.1
3ag2C-5y9dA:
2.2		 3ag2A-5y9dA:
undetectable
3ag2C-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 3ag2N-5y9dA:
2.8
3ag2P-5y9dA:
2.2		 3ag2N-5y9dA:
undetectable
3ag2P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 3ag3A-5y9dA:
2.3
3ag3C-5y9dA:
2.2		 3ag3A-5y9dA:
undetectable
3ag3C-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 3ag3N-5y9dA:
2.0
3ag3P-5y9dA:
2.2		 3ag3N-5y9dA:
undetectable
3ag3P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.14A 3ag4A-5y9dA:
0.7
3ag4C-5y9dA:
2.2		 3ag4A-5y9dA:
undetectable
3ag4C-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 3ag4N-5y9dA:
2.8
3ag4P-5y9dA:
2.2		 3ag4N-5y9dA:
undetectable
3ag4P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 3asnA-5y9dA:
2.3
3asnC-5y9dA:
2.2		 3asnA-5y9dA:
undetectable
3asnC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.10A 3asnC-5y9dA:
2.2
3asnN-5y9dA:
2.7
3asnP-5y9dA:
2.2		 3asnC-5y9dA:
undetectable
3asnN-5y9dA:
undetectable
3asnP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 3asoA-5y9dA:
undetectable
3asoC-5y9dA:
2.2
3asoP-5y9dA:
2.2		 3asoA-5y9dA:
undetectable
3asoC-5y9dA:
undetectable
3asoP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 3asoC-5y9dA:
2.2
3asoN-5y9dA:
1.9
3asoP-5y9dA:
2.2		 3asoC-5y9dA:
undetectable
3asoN-5y9dA:
undetectable
3asoP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 5 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.04A 3bcrA-5y9dA:
undetectable		 3bcrA-5y9dA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 CYH A 197
HIS A 196
PHE A 115
 None
 1.00A 3cr4X-5y9dA:
undetectable		 3cr4X-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.04A 3dd1A-5y9dA:
undetectable		 3dd1A-5y9dA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.05A 3dd1B-5y9dA:
undetectable		 3dd1B-5y9dA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.05A 3ddsA-5y9dA:
undetectable		 3ddsA-5y9dA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.04A 3ddsB-5y9dA:
undetectable		 3ddsB-5y9dA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.02A 3ddwA-5y9dA:
undetectable		 3ddwA-5y9dA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.03A 3ddwB-5y9dA:
undetectable		 3ddwB-5y9dA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 ARG A 242
ILE A 412
TRP A 437
 None
 1.21A 3e6tB-5y9dA:
0.0		 3e6tB-5y9dA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 10 ILE A 332
ILE A 331
GLY A 420
VAL A 645
LEU A 341
 None
 1.25A 3elzB-5y9dA:
undetectable		 3elzB-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 5 ILE A 514
THR A 549
PHE A 403
PHE A 542
 None
 1.33A 3em0A-5y9dA:
undetectable		 3em0A-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 SER A 538
GLN A 539
PHE A 542
 FAD  A 701 ( 4.9A)
None
None
 0.69A 3g4lC-5y9dA:
undetectable		 3g4lC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 12 LEU A 307
LEU A 311
PHE A 627
LEU A 575
THR A  28
 None
 1.20A 3gwuA-5y9dA:
undetectable		 3gwuA-5y9dA:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 12 PHE A 542
PHE A 506
PHE A 579
ALA A 346
ILE A 411
 None
 1.11A 3nxuB-5y9dA:
undetectable		 3nxuB-5y9dA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 GLN A  21
THR A  20
LEU A 572
 None
 0.75A 3ondA-5y9dA:
undetectable		 3ondA-5y9dA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 GLN A  21
THR A  20
LEU A 572
 None
 0.76A 3ondB-5y9dA:
undetectable		 3ondB-5y9dA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 9 LEU A 629
ASP A 101
GLY A 433
ILE A 412
ILE A 634
 None
 1.06A 3s56B-5y9dA:
undetectable		 3s56B-5y9dA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 5 ASN A 428
ALA A 636
PRO A 637
TYR A  60
 None
 1.42A 3twpD-5y9dA:
undetectable		 3twpD-5y9dA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 3wg7A-5y9dA:
2.9
3wg7C-5y9dA:
2.2
3wg7P-5y9dA:
2.2		 3wg7A-5y9dA:
undetectable
3wg7C-5y9dA:
undetectable
3wg7P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.10A 3wg7C-5y9dA:
2.2
3wg7N-5y9dA:
1.1
3wg7P-5y9dA:
2.2		 3wg7C-5y9dA:
undetectable
3wg7N-5y9dA:
undetectable
3wg7P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.15A 3x2qA-5y9dA:
0.3
3x2qC-5y9dA:
2.2
3x2qP-5y9dA:
2.2		 3x2qA-5y9dA:
undetectable
3x2qC-5y9dA:
undetectable
3x2qP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 3x2qC-5y9dA:
2.2
3x2qN-5y9dA:
2.2
3x2qP-5y9dA:
2.2		 3x2qC-5y9dA:
undetectable
3x2qN-5y9dA:
undetectable
3x2qP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 12 ASP A 436
GLY A 244
SER A 103
GLY A 429
ASP A 101
 None
 1.24A 4blvB-5y9dA:
undetectable		 4blvB-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 4 PRO A  52
LEU A  54
ILE A  48
ARG A  93
 None
 1.21A 4f4dA-5y9dA:
undetectable		 4f4dA-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JI8_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 LYS A  88
LYS A 360
TRP A  92
 None
 1.31A 4ji8L-5y9dA:
undetectable		 4ji8L-5y9dA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 12 PHE A 627
GLU A  16
GLN A 619
VAL A  24
LEU A  31
 None
 1.39A 4k38B-5y9dA:
undetectable		 4k38B-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 12 PHE A 627
GLU A  16
GLN A 619
VAL A  24
LEU A  31
 None
 1.40A 4k39A-5y9dA:
undetectable		 4k39A-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 5 PRO A  52
LEU A  54
ILE A  48
ARG A  93
 None
 1.06A 4klrA-5y9dA:
undetectable		 4klrA-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 12 ILE A 331
LEU A 342
PRO A 343
LEU A 311
ILE A 332
 None
 1.05A 4m2xE-5y9dA:
undetectable		 4m2xE-5y9dA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		6 / 12 TYR A  60
GLY A 433
GLY A 431
ILE A 309
ASN A 428
ASN A 635
 None
 1.29A 4obwB-5y9dA:
undetectable		 4obwB-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 5 ILE A 233
VAL A 231
PHE A 215
HIS A 192
 None
 1.23A 4rzvA-5y9dA:
undetectable		 4rzvA-5y9dA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.14A 5b1aA-5y9dA:
0.8
5b1aC-5y9dA:
2.2
5b1aP-5y9dA:
2.2		 5b1aA-5y9dA:
undetectable
5b1aC-5y9dA:
undetectable
5b1aP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 5b1aN-5y9dA:
1.0
5b1aP-5y9dA:
undetectable		 5b1aN-5y9dA:
undetectable
5b1aP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.14A 5b1bA-5y9dA:
0.1
5b1bC-5y9dA:
2.2
5b1bP-5y9dA:
2.2		 5b1bA-5y9dA:
undetectable
5b1bC-5y9dA:
undetectable
5b1bP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 5b1bN-5y9dA:
2.9
5b1bP-5y9dA:
2.2		 5b1bN-5y9dA:
undetectable
5b1bP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 5b3sA-5y9dA:
1.9
5b3sC-5y9dA:
2.2
5b3sP-5y9dA:
2.2		 5b3sA-5y9dA:
undetectable
5b3sC-5y9dA:
undetectable
5b3sP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.10A 5b3sN-5y9dA:
1.9
5b3sP-5y9dA:
undetectable		 5b3sN-5y9dA:
undetectable
5b3sP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 5iy5A-5y9dA:
undetectable
5iy5C-5y9dA:
2.2		 5iy5A-5y9dA:
undetectable
5iy5C-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 5iy5C-5y9dA:
2.2
5iy5N-5y9dA:
2.9
5iy5P-5y9dA:
2.2		 5iy5C-5y9dA:
undetectable
5iy5N-5y9dA:
undetectable
5iy5P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 12 PHE A 633
GLY A 628
THR A  28
ASN A  32
HIS A 301
 None
 1.11A 5kocB-5y9dA:
undetectable		 5kocB-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		5 / 12 ASN A 448
VAL A 449
GLY A 455
ILE A 514
SER A 461
 None
 1.35A 5lsaA-5y9dA:
undetectable		 5lsaA-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASN A 113
LEU A 114
ARG A 107
GLY A 188
 None
None
None
FAD  A 701 (-3.9A)
 1.07A 5o4yA-5y9dA:
undetectable		 5o4yA-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 VAL A 198
VAL A 216
GLN A 127
 None
 0.67A 5qgyA-5y9dA:
undetectable		 5qgyA-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		3 / 3 VAL A 198
VAL A 216
GLN A 127
 None
 0.66A 5qh0A-5y9dA:
undetectable		 5qh0A-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.10A 5w97A-5y9dA:
1.1
5w97C-5y9dA:
2.2
5w97c-5y9dA:
2.2		 5w97A-5y9dA:
undetectable
5w97C-5y9dA:
undetectable
5w97c-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.09A 5w97C-5y9dA:
2.2
5w97a-5y9dA:
1.1
5w97c-5y9dA:
2.2		 5w97C-5y9dA:
undetectable
5w97a-5y9dA:
undetectable
5w97c-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 5wauA-5y9dA:
2.1
5wauC-5y9dA:
2.2
5wauc-5y9dA:
2.2		 5wauA-5y9dA:
undetectable
5wauC-5y9dA:
undetectable
5wauc-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 5wauC-5y9dA:
2.2
5waua-5y9dA:
2.1
5wauc-5y9dA:
2.2		 5wauC-5y9dA:
undetectable
5waua-5y9dA:
undetectable
5wauc-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.09A 5x19A-5y9dA:
undetectable
5x19C-5y9dA:
2.2
5x19P-5y9dA:
2.2		 5x19A-5y9dA:
undetectable
5x19C-5y9dA:
undetectable
5x19P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.06A 5x19N-5y9dA:
3.0
5x19P-5y9dA:
2.2		 5x19N-5y9dA:
undetectable
5x19P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.07A 5x1bA-5y9dA:
3.0
5x1bC-5y9dA:
2.1
5x1bP-5y9dA:
2.2		 5x1bA-5y9dA:
undetectable
5x1bC-5y9dA:
undetectable
5x1bP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.10A 5x1bN-5y9dA:
2.2
5x1bP-5y9dA:
2.2		 5x1bN-5y9dA:
undetectable
5x1bP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.10A 5x1fA-5y9dA:
2.1
5x1fC-5y9dA:
2.2
5x1fP-5y9dA:
1.4		 5x1fA-5y9dA:
undetectable
5x1fC-5y9dA:
undetectable
5x1fP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 5x1fN-5y9dA:
2.0
5x1fP-5y9dA:
1.4		 5x1fN-5y9dA:
undetectable
5x1fP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 5xdqA-5y9dA:
0.1
5xdqC-5y9dA:
2.3
5xdqP-5y9dA:
2.2		 5xdqA-5y9dA:
undetectable
5xdqC-5y9dA:
undetectable
5xdqP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 5xdqC-5y9dA:
2.3
5xdqN-5y9dA:
2.6
5xdqP-5y9dA:
2.2		 5xdqC-5y9dA:
undetectable
5xdqN-5y9dA:
undetectable
5xdqP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 5xdxC-5y9dA:
1.9
5xdxN-5y9dA:
2.7
5xdxP-5y9dA:
2.2		 5xdxC-5y9dA:
undetectable
5xdxN-5y9dA:
undetectable
5xdxP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 5z84A-5y9dA:
0.6
5z84C-5y9dA:
2.2
5z84P-5y9dA:
2.2		 5z84A-5y9dA:
undetectable
5z84C-5y9dA:
undetectable
5z84P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 5z84C-5y9dA:
2.2
5z84N-5y9dA:
2.7
5z84P-5y9dA:
2.2		 5z84C-5y9dA:
undetectable
5z84N-5y9dA:
undetectable
5z84P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.15A 5z85A-5y9dA:
2.7
5z85C-5y9dA:
2.2
5z85P-5y9dA:
2.2		 5z85A-5y9dA:
undetectable
5z85C-5y9dA:
undetectable
5z85P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.14A 5z85C-5y9dA:
2.2
5z85N-5y9dA:
2.9
5z85P-5y9dA:
2.2		 5z85C-5y9dA:
undetectable
5z85N-5y9dA:
undetectable
5z85P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.14A 5z86A-5y9dA:
2.9
5z86C-5y9dA:
2.2
5z86P-5y9dA:
2.2		 5z86A-5y9dA:
undetectable
5z86C-5y9dA:
undetectable
5z86P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.14A 5z86C-5y9dA:
2.2
5z86N-5y9dA:
1.9
5z86P-5y9dA:
2.2		 5z86C-5y9dA:
undetectable
5z86N-5y9dA:
undetectable
5z86P-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 5zcoA-5y9dA:
0.3
5zcoC-5y9dA:
2.2
5zcoP-5y9dA:
1.4		 5zcoA-5y9dA:
undetectable
5zcoC-5y9dA:
undetectable
5zcoP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 5zcoC-5y9dA:
2.2
5zcoN-5y9dA:
2.7
5zcoP-5y9dA:
undetectable		 5zcoC-5y9dA:
undetectable
5zcoN-5y9dA:
undetectable
5zcoP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.15A 5zcpA-5y9dA:
1.9
5zcpC-5y9dA:
2.2
5zcpP-5y9dA:
2.2		 5zcpA-5y9dA:
undetectable
5zcpC-5y9dA:
undetectable
5zcpP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.14A 5zcpC-5y9dA:
2.2
5zcpN-5y9dA:
2.9
5zcpP-5y9dA:
2.2		 5zcpC-5y9dA:
undetectable
5zcpN-5y9dA:
undetectable
5zcpP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 5zcqA-5y9dA:
undetectable
5zcqC-5y9dA:
2.2
5zcqP-5y9dA:
2.2		 5zcqA-5y9dA:
undetectable
5zcqC-5y9dA:
undetectable
5zcqP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.13A 5zcqN-5y9dA:
2.0
5zcqP-5y9dA:
undetectable		 5zcqN-5y9dA:
undetectable
5zcqP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.08A 6nknA-5y9dA:
2.9
6nknC-5y9dA:
2.1		 6nknA-5y9dA:
undetectable
6nknC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 8 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.10A 6nknC-5y9dA:
2.1
6nknN-5y9dA:
0.0
6nknP-5y9dA:
2.1		 6nknC-5y9dA:
undetectable
6nknN-5y9dA:
undetectable
6nknP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.12A 6nmfA-5y9dA:
1.1
6nmfC-5y9dA:
2.1
6nmfP-5y9dA:
2.1		 6nmfA-5y9dA:
undetectable
6nmfC-5y9dA:
undetectable
6nmfP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.10A 6nmfN-5y9dA:
undetectable
6nmfP-5y9dA:
2.1		 6nmfN-5y9dA:
undetectable
6nmfP-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 6 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.14A 6nmpA-5y9dA:
undetectable
6nmpC-5y9dA:
2.1		 6nmpA-5y9dA:
undetectable
6nmpC-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y9d ACYL-COENZYME A
OXIDASE 1
(Yarrowia
lipolytica) 		4 / 7 ASP A 519
THR A 518
TYR A 521
HIS A 548
 None
 1.11A 6nmpN-5y9dA:
3.0
6nmpP-5y9dA:
2.2		 6nmpN-5y9dA:
undetectable
6nmpP-5y9dA:
undetectable