SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_1
(ALCOHOL
DEHYDROGENASE)		 5y9p -
(-) 		4 / 4 GLU A 221
MET A 208
LEU A 211
SER A 212
 None
 0.80A 1ee2B-5y9pA:
undetectable		 1ee2B-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 5y9p -
(-) 		3 / 3 MET A 208
LEU A 211
SER A 212
 None
 0.35A 1ee2A-5y9pA:
undetectable		 1ee2A-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 5y9p -
(-) 		5 / 10 GLY A  81
VAL A  89
ILE A 145
ARG A  82
GLY A  83
 None
 1.22A 1fohA-5y9pA:
undetectable		 1fohA-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 5y9p -
(-) 		5 / 10 GLY A  81
VAL A  89
ILE A 145
ARG A  82
GLY A  83
 None
 1.24A 1fohB-5y9pA:
undetectable		 1fohB-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 5y9p -
(-) 		5 / 10 GLY A  81
VAL A  89
ILE A 145
ARG A  82
GLY A  83
 None
 1.28A 1fohC-5y9pA:
undetectable		 1fohC-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)		 5y9p -
(-) 		5 / 10 GLY A  81
VAL A  89
ILE A 145
ARG A  82
GLY A  83
 None
 1.26A 1fohD-5y9pA:
undetectable		 1fohD-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 5y9p -
(-) 		4 / 8 LEU A 211
TYR A 218
GLY A 225
TYR A 207
 None
 1.05A 1jlfA-5y9pA:
3.1
1jlfB-5y9pA:
3.1		 1jlfA-5y9pA:
undetectable
1jlfB-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5y9p -
(-) 		4 / 7 LEU A 211
TYR A 218
GLY A 225
TYR A 207
 None
 1.03A 1lweA-5y9pA:
3.1		 1lweA-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 5y9p -
(-) 		4 / 6 ASN A 223
HIS A 244
TYR A 218
GLY A 227
 None
 1.38A 1mxdA-5y9pA:
undetectable		 1mxdA-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 5y9p -
(-) 		5 / 10 LEU A 119
VAL A 127
GLY A  76
ILE A 193
LEU A 123
 None
 1.19A 3ogpB-5y9pA:
undetectable		 3ogpB-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 5y9p -
(-) 		5 / 9 ASP A 170
ILE A 169
ILE A 151
ILE A 157
ILE A  77
 None
 0.95A 3s43A-5y9pA:
undetectable		 3s43A-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 5y9p -
(-) 		3 / 3 LEU A 119
MET A 199
ASP A  78
 None
 0.55A 3v5wA-5y9pA:
undetectable		 3v5wA-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 5y9p -
(-) 		6 / 12 GLN A 180
ILE A 169
ALA A 156
GLY A 133
ALA A  93
ILE A  77
 None
 1.47A 5kb6A-5y9pA:
undetectable		 5kb6A-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 5y9p -
(-) 		6 / 12 GLN A 180
ILE A 169
ALA A 156
GLY A 133
ALA A  93
ILE A  77
 None
 1.47A 5kb6B-5y9pA:
undetectable		 5kb6B-5y9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 5y9p -
(-) 		5 / 12 TYR A  55
ILE A  65
LEU A 167
VAL A 181
SER A 190
 None
 1.37A 5l8oB-5y9pA:
1.0		 5l8oB-5y9pA:
undetectable