SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 5y9v RYANODINE RECEPTOR 1
(Plutella
xylostella) 		6 / 11 PHE A  65
LEU A  25
ALA A 189
VAL A 198
LEU A  17
LEU A 146
 None
 1.39A 1rlbF-5y9vA:
undetectable		 1rlbF-5y9vA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 5y9v RYANODINE RECEPTOR 1
(Plutella
xylostella) 		4 / 6 PHE A 129
ALA A 128
LEU A 127
SER A 121
 None
 0.79A 1sbrA-5y9vA:
undetectable
1sbrB-5y9vA:
undetectable		 1sbrA-5y9vA:
17.10
1sbrB-5y9vA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 5y9v RYANODINE RECEPTOR 1
(Plutella
xylostella) 		5 / 12 VAL A 187
LEU A  25
SER A  26
LEU A 176
LEU A  48
 None
 1.21A 1ya4B-5y9vA:
undetectable		 1ya4B-5y9vA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 5y9v RYANODINE RECEPTOR 1
(Plutella
xylostella) 		3 / 3 TYR A 114
GLN A  69
TRP A 144
 None
 1.13A 4kn2C-5y9vA:
undetectable		 4kn2C-5y9vA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 5y9v RYANODINE RECEPTOR 1
(Plutella
xylostella) 		4 / 6 CYH A  46
LEU A  36
HIS A 177
LEU A 176
 None
 0.96A 5hpuC-5y9vA:
undetectable
5hpuD-5y9vA:
undetectable		 5hpuC-5y9vA:
undetectable
5hpuD-5y9vA:
undetectable