SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 5y9w POLLEN RECEPTOR-LIKE
KINASE 6
(Arabidopsis
thaliana) 		4 / 8 ILE B  76
PHE B  37
LEU B  48
VAL B  78
 None
 0.90A 1fslB-5y9wB:
undetectable		 1fslB-5y9wB:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5y9w POLLEN RECEPTOR-LIKE
KINASE 6
(Arabidopsis
thaliana) 		4 / 5 ILE B 101
ILE B 135
ILE B  87
LEU B 170
 None
 0.80A 1zgyA-5y9wB:
undetectable		 1zgyA-5y9wB:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 5y9w POLLEN RECEPTOR-LIKE
KINASE 6
(Arabidopsis
thaliana) 		5 / 12 LEU B 194
LEU B 173
ILE B 212
ASN B 225
LEU B 222
 None
 1.05A 2bdmA-5y9wB:
undetectable		 2bdmA-5y9wB:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 5y9w POLLEN RECEPTOR-LIKE
KINASE 6
(Arabidopsis
thaliana) 		5 / 12 ILE B 135
LEU B 112
LEU B 146
THR B 165
LEU B 173
 None
 1.08A 3a50D-5y9wB:
undetectable		 3a50D-5y9wB:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 5y9w POLLEN RECEPTOR-LIKE
KINASE 6
(Arabidopsis
thaliana) 		5 / 9 LEU B  48
PHE B  63
ARG B 102
LEU B 126
GLY B  64
 None
None
SO4  B 703 (-3.2A)
None
None
 1.20A 3nxuB-5y9wB:
undetectable		 3nxuB-5y9wB:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5y9w POLLEN RECEPTOR-LIKE
KINASE 6
(Arabidopsis
thaliana) 		5 / 12 ILE B 160
MET B 191
ILE B 212
LEU B 222
ILE B 184
 None
 1.10A 4pthA-5y9wB:
undetectable		 4pthA-5y9wB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 5y9w POLLEN RECEPTOR-LIKE
KINASE 6
(Arabidopsis
thaliana) 		4 / 4 LEU B 197
ILE B 212
PRO B 185
LEU B 204
 None
 1.12A 5eb3A-5y9wB:
undetectable		 5eb3A-5y9wB:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 5y9w POLLEN RECEPTOR-LIKE
KINASE 6
(Arabidopsis
thaliana) 		5 / 12 LEU B 112
ILE B 135
LEU B 180
GLY B 158
ILE B 160
 None
 1.12A 5j7wC-5y9wB:
undetectable		 5j7wC-5y9wB:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 5y9w POLLEN RECEPTOR-LIKE
KINASE 6
(Arabidopsis
thaliana) 		5 / 12 GLU B 183
LEU B 197
LEU B 199
ILE B 164
GLU B 187
 None
 1.20A 5v0vA-5y9wB:
undetectable		 5v0vA-5y9wB:
8.58