SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
5 / 12 ILE A  11
ILE A 150
ILE A  70
PHE A  61
VAL A 140
None
0.99A 1qhsA-5ybaA:
undetectable
1qhsA-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
3 / 3 TYR A  56
GLY A  58
PHE A  75
None
0.60A 2m2pB-5ybaA:
undetectable
2m2pB-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
4 / 6 PHE A  23
PHE A  37
GLY A  72
GLY A  73
None
0.87A 2qr2A-5ybaA:
undetectable
2qr2B-5ybaA:
undetectable
2qr2A-5ybaA:
undetectable
2qr2B-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
4 / 5 GLY A  72
GLY A  73
PHE A  23
PHE A  37
None
0.80A 2qr2A-5ybaA:
undetectable
2qr2B-5ybaA:
undetectable
2qr2A-5ybaA:
undetectable
2qr2B-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
4 / 8 PHE A  23
PHE A  37
GLY A  72
GLY A  73
None
0.75A 2qx4A-5ybaA:
undetectable
2qx4B-5ybaA:
undetectable
2qx4A-5ybaA:
undetectable
2qx4B-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
4 / 6 PHE A  23
PHE A  37
GLY A  72
GLY A  73
None
0.75A 2qx6A-5ybaA:
undetectable
2qx6B-5ybaA:
undetectable
2qx6A-5ybaA:
undetectable
2qx6B-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
4 / 6 THR A 127
SER A 107
LEU A 105
THR A 123
None
0.84A 3deuB-5ybaA:
undetectable
3deuB-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
5 / 9 PHE A  37
PHE A 137
PHE A   9
GLY A  72
THR A  59
None
1.21A 3t3rB-5ybaA:
undetectable
3t3rB-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
5 / 9 PHE A  37
PHE A 137
PHE A   9
GLY A  73
THR A  59
None
1.12A 3t3rB-5ybaA:
undetectable
3t3rB-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
5 / 10 PHE A  23
PHE A 137
PHE A   9
GLY A  72
THR A  59
None
1.30A 3t3rD-5ybaA:
undetectable
3t3rD-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
4 / 5 PHE A  23
GLY A  73
THR A  59
VAL A 166
None
1.05A 3wrkD-5ybaA:
undetectable
3wrkD-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
4 / 6 ALA A  34
ASN A  27
LEU A  25
ASP A  28
None
1.03A 4g24A-5ybaA:
undetectable
4g24A-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
5 / 12 GLY A 117
ILE A  86
ASN A 110
PHE A  37
LEU A 106
None
1.06A 5fa8A-5ybaA:
undetectable
5fa8A-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
5 / 10 ILE A 150
PHE A  23
GLY A  72
GLY A  73
TYR A  56
None
1.40A 5lbtA-5ybaA:
undetectable
5lbtB-5ybaA:
undetectable
5lbtA-5ybaA:
undetectable
5lbtB-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AGG_Z_AG2Z503_0
(TRNA(ILE2)
2-AGMATINYLCYTIDINE
SYNTHETASE TIAS)
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
4 / 5 GLU A  24
ASN A  27
VAL A  30
ARG A   4
None
1.49A 6aggZ-5ybaA:
undetectable
6aggZ-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis)
3 / 3 GLY A 158
THR A 155
GLU A 156
None
0.61A 6b58A-5ybaA:
undetectable
6b58A-5ybaA:
undetectable