SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ybv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 5ybv KINESIN-LIKE PROTEIN
KIF21A
KN MOTIF AND ANKYRIN
REPEAT
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 7 LEU C1163
ALA A 709
LEU A 707
SER A 674
 None
 0.68A 1dvxA-5ybvC:
undetectable		 1dvxA-5ybvC:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5ybv KN MOTIF AND ANKYRIN
REPEAT
DOMAIN-CONTAINING
PROTEIN 2
KINESIN-LIKE PROTEIN
KIF21A
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP A 771
ARG C1155
LYS C1152
 None
 1.02A 3wipG-5ybvA:
undetectable		 3wipG-5ybvA:
undetectable