SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yd0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 5yd0 SCHLAFEN 8
(Rattus
norvegicus) 		4 / 6 CYH A 283
VAL A 158
HIS A 281
CYH A 318
 ZN  A 900 (-2.8A)
None
ZN  A 900 (-3.0A)
ZN  A 900 (-2.5A)
 1.49A 1ekjG-5yd0A:
undetectable
1ekjH-5yd0A:
undetectable		 1ekjG-5yd0A:
undetectable
1ekjH-5yd0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 5yd0 SCHLAFEN 8
(Rattus
norvegicus) 		4 / 7 LEU A 201
LEU A 254
GLY A 198
LEU A 195
 None
 0.87A 1gtiB-5yd0A:
undetectable		 1gtiB-5yd0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 5yd0 SCHLAFEN 8
(Rattus
norvegicus) 		4 / 4 GLY A  75
LEU A  78
GLY A  26
ARG A  30
 None
 0.99A 1j7kA-5yd0A:
undetectable		 1j7kA-5yd0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 5yd0 SCHLAFEN 8
(Rattus
norvegicus) 		3 / 3 PRO A 325
SER A 327
ASN A 340
 None
 0.80A 3lslG-5yd0A:
undetectable		 3lslG-5yd0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5yd0 SCHLAFEN 8
(Rattus
norvegicus) 		4 / 6 GLY A 239
GLY A 240
ASN A 184
ILE A 231
 None
 0.91A 4fglD-5yd0A:
undetectable		 4fglD-5yd0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 5yd0 SCHLAFEN 8
(Rattus
norvegicus) 		4 / 6 LEU A  78
LEU A  82
GLU A  79
ILE A 106
 None
 0.93A 4ww7A-5yd0A:
undetectable		 4ww7A-5yd0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5yd0 SCHLAFEN 8
(Rattus
norvegicus) 		4 / 4 LEU A  78
LEU A  25
GLY A  26
GLU A  27
 None
 1.29A 5hhjA-5yd0A:
undetectable		 5hhjA-5yd0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 5yd0 SCHLAFEN 8
(Rattus
norvegicus) 		5 / 12 SER A 126
THR A 147
PRO A 325
PHE A 321
LEU A 131
 None
 1.37A 5jo9A-5yd0A:
undetectable		 5jo9A-5yd0A:
undetectable