SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ydf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 5ydf PARAFIBROMIN
(Homo
sapiens) 		5 / 12 PHE A  27
VAL A  25
ASN A  66
VAL A  86
LEU A   8
 None
 1.09A 2ft9A-5ydfA:
undetectable		 2ft9A-5ydfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ydf PARAFIBROMIN
(Homo
sapiens) 		5 / 12 LEU A  61
THR A  38
LEU A  94
LEU A  98
PHE A  27
 None
 1.33A 3g1uB-5ydfA:
undetectable		 3g1uB-5ydfA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ydf PARAFIBROMIN
(Homo
sapiens) 		5 / 12 LEU A  61
THR A  38
LEU A  94
LEU A  98
PHE A  27
 None
 1.32A 3g1uD-5ydfA:
undetectable		 3g1uD-5ydfA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 5ydf PARAFIBROMIN
(Homo
sapiens) 		4 / 7 ILE A  60
LEU A  94
ASP A  93
ASP A  90
 None
 1.06A 4mmcA-5ydfA:
undetectable		 4mmcA-5ydfA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 5ydf PARAFIBROMIN
(Homo
sapiens) 		3 / 3 ASP A  90
TYR A  40
TRP A  43
 None
 1.15A 4p7nA-5ydfA:
undetectable		 4p7nA-5ydfA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5ydf PARAFIBROMIN
(Homo
sapiens) 		4 / 6 LEU A  57
SER A  31
PHE A  30
GLU A  29
 None
 1.18A 5b8iA-5ydfA:
undetectable		 5b8iA-5ydfA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 5ydf PARAFIBROMIN
(Homo
sapiens) 		4 / 5 LEU A   8
LEU A  94
THR A  56
ARG A  77
 None
 0.82A 6ew0F-5ydfA:
undetectable		 6ew0F-5ydfA:
21.74