SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ydg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DGM_A_ADNA375_1
(ADENOSINE KINASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ASP A 161
GLY A 138
ASN A 128
LEU A 159
TYR A 108
 None
 1.41A 1dgmA-5ydgA:
undetectable		 1dgmA-5ydgA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLU A 174
ARG A 184
GLY A 138
TYR A 108
GLY A 136
 None
 1.25A 1httB-5ydgA:
undetectable		 1httB-5ydgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 GLY A 172
GLY A 136
LEU A  88
SER A 130
GLY A 138
 None
 1.26A 1jhoA-5ydgA:
undetectable		 1jhoA-5ydgA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 GLY A 172
GLY A 136
LEU A  88
SER A 130
GLY A 138
 None
 1.28A 1jhrA-5ydgA:
undetectable		 1jhrA-5ydgA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 GLY A 172
GLY A 136
LEU A  88
SER A 130
GLY A 138
 None
 1.29A 1jhyA-5ydgA:
undetectable		 1jhyA-5ydgA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 GLY A 172
GLY A 136
LEU A  88
SER A 130
GLY A 138
 None
 1.29A 1l4nA-5ydgA:
undetectable		 1l4nA-5ydgA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 GLY A 172
GLY A 136
LEU A  88
SER A 130
GLY A 138
 None
 1.27A 1l5kA-5ydgA:
undetectable		 1l5kA-5ydgA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 GLY A 172
GLY A 136
LEU A  88
SER A 130
GLY A 138
 None
 1.27A 1l5lA-5ydgA:
undetectable		 1l5lA-5ydgA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 GLY A 172
GLY A 136
LEU A  88
SER A 130
GLY A 138
 None
 1.28A 1l5mA-5ydgA:
undetectable		 1l5mA-5ydgA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A 126
PHE A 176
GLY A 179
ILE A 109
GLU A 119
 None
 1.32A 1mrgA-5ydgA:
undetectable		 1mrgA-5ydgA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 PHE A 176
GLY A 179
ILE A 109
ALA A 113
GLU A 119
 None
 1.26A 1mrgA-5ydgA:
undetectable		 1mrgA-5ydgA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 GLU A 119
ASP A 106
GLN A 110
ILE A 126
 None
 0.91A 4ii8A-5ydgA:
undetectable		 4ii8A-5ydgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 GLY A 172
GLY A 136
LEU A  88
SER A 130
GLY A 138
 None
 1.32A 4kqiA-5ydgA:
undetectable		 4kqiA-5ydgA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ALA A 122
ILE A  89
GLY A 138
THR A 145
VAL A 116
 None
 1.16A 4nptA-5ydgA:
undetectable		 4nptA-5ydgA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A 126
PHE A 176
GLY A 179
ILE A 109
GLU A 119
 None
 1.23A 4yp2B-5ydgA:
undetectable		 4yp2B-5ydgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 PHE A 176
GLY A 179
ILE A 109
ALA A 113
GLU A 119
 None
 1.21A 4yp2B-5ydgA:
undetectable		 4yp2B-5ydgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A 126
PHE A 176
GLY A 179
ILE A 109
GLU A 119
 None
 1.24A 5cf9B-5ydgA:
undetectable		 5cf9B-5ydgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 PHE A 176
GLY A 179
ILE A 109
ALA A 113
GLU A 119
 None
 1.20A 5cf9B-5ydgA:
undetectable		 5cf9B-5ydgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLU A 174
ARG A 184
GLY A 138
TYR A 108
GLY A 136
 None
 1.18A 5e3iA-5ydgA:
undetectable		 5e3iA-5ydgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 5ydg MULTIPLE ORGANELLAR
RNA EDITING FACTOR
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 GLU A 174
ARG A 184
GLY A 138
TYR A 108
GLY A 136
 None
 1.19A 5e3iB-5ydgA:
undetectable		 5e3iB-5ydgA:
undetectable