SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ydp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 6 ILE A 205
LEU A 108
ARG A 181
THR A 153
 None
 1.09A 3wg7A-5ydpA:
undetectable
3wg7J-5ydpA:
undetectable		 3wg7A-5ydpA:
18.45
3wg7J-5ydpA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 6 ILE A 205
ARG A 181
THR A 153
LEU A 156
 None
 1.04A 3wg7N-5ydpA:
undetectable
3wg7W-5ydpA:
undetectable		 3wg7N-5ydpA:
18.45
3wg7W-5ydpA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 6 GLY A 146
ARG A 173
GLU A 154
ARG A 151
 None
 1.23A 4bqfA-5ydpA:
undetectable		 4bqfA-5ydpA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		5 / 10 ALA A 159
ILE A  93
ALA A 175
ALA A 176
ILE A 179
 None
 0.90A 4lbgA-5ydpA:
undetectable		 4lbgA-5ydpA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		5 / 9 ALA A 159
ILE A  93
ALA A 175
ALA A 176
ILE A 179
 None
 0.94A 4lbgB-5ydpA:
undetectable		 4lbgB-5ydpA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		5 / 9 LEU A  67
GLY A  76
VAL A  35
VAL A  56
LEU A  42
 None
 1.22A 4qd3A-5ydpA:
undetectable		 4qd3A-5ydpA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 6 ILE A 205
LEU A 108
ARG A 181
THR A 153
 None
 0.96A 5b1aN-5ydpA:
undetectable
5b1aW-5ydpA:
undetectable		 5b1aN-5ydpA:
18.45
5b1aW-5ydpA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 7 ILE A 205
ARG A 181
THR A 153
LEU A 156
 None
 1.00A 5b1bA-5ydpA:
2.1
5b1bJ-5ydpA:
undetectable		 5b1bA-5ydpA:
18.45
5b1bJ-5ydpA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 4 LEU A  83
LEU A 148
GLY A 146
GLU A 150
 None
 1.18A 5hhjA-5ydpA:
undetectable		 5hhjA-5ydpA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 7 ILE A 205
ARG A 181
THR A 153
LEU A 156
 None
 0.97A 5iy5A-5ydpA:
undetectable
5iy5J-5ydpA:
undetectable		 5iy5A-5ydpA:
18.45
5iy5J-5ydpA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 6 ILE A 104
VAL A 213
TRP A 164
SER A 163
 None
 0.99A 5jwaH-5ydpA:
undetectable		 5jwaH-5ydpA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 6 ILE A 205
ARG A 181
THR A 153
LEU A 156
 None
 1.01A 5z86N-5ydpA:
undetectable
5z86W-5ydpA:
undetectable		 5z86N-5ydpA:
18.45
5z86W-5ydpA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 6 ILE A 205
ARG A 181
THR A 153
LEU A 156
 None
 0.98A 5zcoN-5ydpA:
undetectable
5zcoW-5ydpA:
undetectable		 5zcoN-5ydpA:
18.45
5zcoW-5ydpA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN
(Dietzia
sp.
DQ12-45-1b) 		4 / 6 ILE A 205
LEU A 108
ARG A 181
THR A 153
 None
 1.13A 6nmfN-5ydpA:
undetectable
6nmfW-5ydpA:
undetectable		 6nmfN-5ydpA:
18.45
6nmfW-5ydpA:
14.69