SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yeg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 5yeg TRANSCRIPTIONAL
REPRESSOR CTCF
(Homo
sapiens) 		4 / 5 HIS B 425
CYH B 409
ILE B 411
HIS B 430
 ZN  B 502 (-3.3A)
ZN  B 502 (-2.3A)
ZN  B 502 ( 4.8A)
ZN  B 502 (-3.3A)
 1.49A 3qpkA-5yegB:
undetectable		 3qpkA-5yegB:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB601_0
(LACCASE-1)		 5yeg TRANSCRIPTIONAL
REPRESSOR CTCF
(Homo
sapiens) 		4 / 4 HIS B 425
CYH B 409
ILE B 411
HIS B 430
 ZN  B 502 (-3.3A)
ZN  B 502 (-2.3A)
ZN  B 502 ( 4.8A)
ZN  B 502 (-3.3A)
 1.48A 3qpkB-5yegB:
undetectable		 3qpkB-5yegB:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5yeg TRANSCRIPTIONAL
REPRESSOR CTCF
(Homo
sapiens) 		3 / 3 ARG B 389
LYS B 393
ARG B 368
 None
 1.26A 3w1wA-5yegB:
undetectable
3w1wB-5yegB:
undetectable		 3w1wA-5yegB:
16.99
3w1wB-5yegB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5yeg TRANSCRIPTIONAL
REPRESSOR CTCF
(Homo
sapiens) 		3 / 3 ARG B 368
ARG B 389
LYS B 393
 None
 1.33A 3w1wA-5yegB:
undetectable
3w1wB-5yegB:
undetectable		 3w1wA-5yegB:
16.99
3w1wB-5yegB:
16.99