SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yeu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5yeu -
(-) 		4 / 5 PHE A 491
TYR A 511
LEU A 454
VAL A 462
 None
 1.42A 1dz6A-5yeuA:
undetectable		 1dz6A-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 5yeu -
(-) 		4 / 6 ALA A 192
LEU A 315
SER A 196
THR A 193
 MG  A 602 ( 4.7A)
None
None
MG  A 602 ( 4.0A)
 1.12A 1tyrA-5yeuA:
undetectable		 1tyrA-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 5yeu -
(-) 		3 / 3 TYR A 339
TYR A 233
ILE A 336
 None
 0.78A 3eteA-5yeuA:
undetectable
3eteB-5yeuA:
undetectable		 3eteA-5yeuA:
undetectable
3eteB-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5yeu -
(-) 		4 / 7 TYR A 252
ASN A 163
LEU A 166
ASP A 167
 None
 1.15A 3lslA-5yeuA:
undetectable
3lslD-5yeuA:
undetectable		 3lslA-5yeuA:
undetectable
3lslD-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5yeu -
(-) 		4 / 7 TYR A 252
ASN A 163
LEU A 166
ASP A 167
 None
 1.09A 3lslA-5yeuA:
undetectable
3lslD-5yeuA:
undetectable		 3lslA-5yeuA:
undetectable
3lslD-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 5yeu -
(-) 		4 / 6 TYR A 252
ASN A 163
LEU A 166
ASP A 167
 None
 1.05A 3lslG-5yeuA:
undetectable		 3lslG-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5yeu -
(-) 		4 / 4 ILE A 391
LEU A 370
LYS A 389
ASN A 417
 None
 1.22A 4g19D-5yeuA:
undetectable		 4g19D-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 5yeu -
(-) 		5 / 12 TYR A 461
PHE A 491
LEU A 475
LEU A 211
LEU A 499
 None
 1.19A 4j03A-5yeuA:
undetectable		 4j03A-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5yeu -
(-) 		4 / 6 LEU A 283
SER A 242
PHE A 243
GLU A 363
 None
 1.15A 5b8iA-5yeuA:
undetectable		 5b8iA-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 5yeu -
(-) 		5 / 9 LEU A 219
GLY A 218
LEU A 212
LEU A 475
GLU A 480
 None
 1.24A 5dqfA-5yeuA:
undetectable		 5dqfA-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5yeu -
(-) 		3 / 3 ARG A 161
HIS A 158
ARG A 162
 None
 0.94A 5iaoC-5yeuA:
undetectable		 5iaoC-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5yeu -
(-) 		3 / 3 ARG A 161
HIS A 158
ARG A 162
 None
 0.92A 5iaoF-5yeuA:
undetectable		 5iaoF-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5yeu -
(-) 		3 / 3 LYS A 442
LEU A 440
ARG A 286
 None
 0.74A 5yw0A-5yeuA:
undetectable		 5yw0A-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)		 5yeu -
(-) 		5 / 12 LEU A 454
LEU A 190
PHE A 458
ILE A 210
VAL A 209
 None
 1.28A 6debB-5yeuA:
undetectable		 6debB-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5yeu -
(-) 		4 / 6 VAL A 462
LEU A 475
LEU A 472
HIS A 468
 None
 0.85A 6e43A-5yeuA:
undetectable		 6e43A-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5yeu -
(-) 		4 / 6 VAL A 462
LEU A 475
LEU A 472
HIS A 468
 None
 0.88A 6e43B-5yeuA:
undetectable		 6e43B-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5yeu -
(-) 		4 / 6 VAL A 462
LEU A 475
LEU A 472
HIS A 468
 None
 0.86A 6e43C-5yeuA:
undetectable		 6e43C-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5yeu -
(-) 		4 / 6 VAL A 462
LEU A 475
LEU A 472
HIS A 468
 None
 0.88A 6e43D-5yeuA:
undetectable		 6e43D-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 5yeu -
(-) 		3 / 3 TYR A 139
HIS A 397
PHE A 243
 None
 0.98A 6esmA-5yeuA:
undetectable		 6esmA-5yeuA:
undetectable