SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ygf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5ygf GH18329P
(Drosophila
melanogaster) 		5 / 10 VAL A 276
ILE A 403
LEU A 384
VAL A 448
LEU A 450
 None
 1.07A 3gwxA-5ygfA:
undetectable		 3gwxA-5ygfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5ygf GH18329P
(Drosophila
melanogaster) 		3 / 3 THR A 433
ASP A 348
GLU A 331
 None
 0.85A 3qowA-5ygfA:
undetectable		 3qowA-5ygfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 5ygf GH18329P
(Drosophila
melanogaster) 		4 / 7 VAL A 265
LEU A 384
MET A 465
ILE A 461
 None
 0.86A 3rfmA-5ygfA:
undetectable		 3rfmA-5ygfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 5ygf GH18329P
(Drosophila
melanogaster) 		3 / 3 THR A 433
ASP A 348
GLU A 331
 None
 0.83A 5fa8A-5ygfA:
undetectable		 5fa8A-5ygfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 5ygf GH18329P
(Drosophila
melanogaster) 		3 / 3 LYS A 322
ASP A 324
ILE A 365
 None
 0.72A 5kc4E-5ygfA:
undetectable		 5kc4E-5ygfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 5ygf GH18329P
(Drosophila
melanogaster) 		5 / 12 MET A 465
ALA A 404
GLU A 411
LEU A 409
VAL A 268
 None
 1.24A 5vlmB-5ygfA:
undetectable		 5vlmB-5ygfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 5ygf GH18329P
(Drosophila
melanogaster) 		5 / 12 MET A 465
ALA A 404
GLU A 411
LEU A 409
VAL A 268
 None
 1.13A 5vlmH-5ygfA:
undetectable		 5vlmH-5ygfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 5ygf GH18329P
(Drosophila
melanogaster) 		3 / 3 PRO A 399
SER A 401
SER A 402
 None
 0.69A 6bpyA-5ygfA:
undetectable		 6bpyA-5ygfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5ygf GH18329P
(Drosophila
melanogaster) 		5 / 9 SER A 258
GLY A 280
SER A 283
VAL A 263
ILE A 279
 None
 1.26A 6giqA-5ygfA:
undetectable
6giqE-5ygfA:
undetectable
6giqI-5ygfA:
undetectable		 6giqA-5ygfA:
undetectable
6giqE-5ygfA:
undetectable
6giqI-5ygfA:
undetectable