SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ygk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VHU_A_SNLA1001_2 (MINERALOCORTICOID RECEPTOR)	5ygk	- (-)	4 / 5	LEU A 48 LEU A 4 LEU A 7 MET A 29	None None DST A 301 (-4.1A) DST A 302 ( 4.4A)	1.04A	3vhuA-5ygkA: undetectable	3vhuA-5ygkA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZJQ_A_NCAA300_0 (PROTOGLOBIN)	5ygk	- (-)	4 / 7	VAL A 45 PHE A 115 PHE A 36 ILE A 162	None	0.85A	3zjqA-5ygkA: undetectable	3zjqA-5ygkA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZJQ_B_NCAB300_0 (PROTOGLOBIN)	5ygk	- (-)	4 / 7	VAL A 45 PHE A 115 PHE A 36 ILE A 162	None	0.89A	3zjqB-5ygkA: undetectable	3zjqB-5ygkA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_C_DXCC1478_0 (TRANSLATION ELONGATION FACTOR SELB)	5ygk	- (-)	4 / 6	THR A 51 ILE A 50 THR A 193 PHE A 36	DST A 301 (-4.3A) None None None	1.05A	4acbC-5ygkA: 2.3	4acbC-5ygkA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_B_ACTB701_0 (RNA (33-MER) RNA POLYMERASE 3D-POL)	5ygk	- (-)	3 / 3	HIS A 118 GLY A 89 ILE A 120	None	0.64A	4k50A-5ygkA: undetectable	4k50A-5ygkA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_J_ACTJ701_0 (RNA (33-MER) RNA POLYMERASE 3D-POL)	5ygk	- (-)	3 / 3	HIS A 118 GLY A 89 ILE A 120	None	0.63A	4k50I-5ygkA: undetectable	4k50I-5ygkA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LTW_A_STRA301_2 (ANCESTRAL STEROID RECEPTOR 2)	5ygk	- (-)	4 / 8	ALA A 52 PHE A 36 VAL A 45 PHE A 115	None	0.84A	4ltwA-5ygkA: undetectable	4ltwA-5ygkA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3VHU_A_SNLA1001_2","MINERALOCORTICOID RECEPTOR","5ygk","-","-",4,"LEU A  48;LEU A   4;LEU A   7;MET A  29","None;None;DST A 301 (-4.1A);DST A 302 ( 4.4A)","1.04A","3vhuA-5ygkA:undetectable","3vhuA-5ygkA:undetectable"],["3ZJQ_A_NCAA300_0","PROTOGLOBIN","5ygk","-","-",4,"VAL A  45;PHE A 115;PHE A  36;ILE A 162","None","0.85A","3zjqA-5ygkA:undetectable","3zjqA-5ygkA:undetectable"],["3ZJQ_B_NCAB300_0","PROTOGLOBIN","5ygk","-","-",4,"VAL A  45;PHE A 115;PHE A  36;ILE A 162","None","0.89A","3zjqB-5ygkA:undetectable","3zjqB-5ygkA:undetectable"],["4ACB_C_DXCC1478_0","TRANSLATION ELONGATION FACTOR SELB","5ygk","-","-",4,"THR A  51;ILE A  50;THR A 193;PHE A  36","DST A 301 (-4.3A);None;None;None","1.05A","4acbC-5ygkA:2.3","4acbC-5ygkA:undetectable"],["4K50_B_ACTB701_0","RNA (33-MER);RNA POLYMERASE 3D-POL","5ygk","-","-",3,"HIS A 118;GLY A  89;ILE A 120","None","0.64A","4k50A-5ygkA:undetectable","4k50A-5ygkA:undetectable"],["4K50_J_ACTJ701_0","RNA (33-MER);RNA POLYMERASE 3D-POL","5ygk","-","-",3,"HIS A 118;GLY A  89;ILE A 120","None","0.63A","4k50I-5ygkA:undetectable","4k50I-5ygkA:undetectable"],["4LTW_A_STRA301_2","ANCESTRAL STEROID RECEPTOR 2","5ygk","-","-",4,"ALA A  52;PHE A  36;VAL A  45;PHE A 115","None","0.84A","4ltwA-5ygkA:undetectable","4ltwA-5ygkA:undetectable"]]