SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yhb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5yhb POLYHEDRIN
(Cypovirus
1) 		3 / 3 LYS A 135
TYR A 136
ARG A 139
 None
 1.19A 4gc9A-5yhbA:
undetectable		 4gc9A-5yhbA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5yhb POLYHEDRIN
(Cypovirus
1) 		4 / 5 TYR A 165
ASN A 237
GLU A 217
TYR A 232
 None
 1.44A 4twdC-5yhbA:
undetectable
4twdD-5yhbA:
undetectable		 4twdC-5yhbA:
21.71
4twdD-5yhbA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5yhb POLYHEDRIN
(Cypovirus
1) 		4 / 6 TYR A 165
ASN A 237
GLU A 217
TYR A 232
 None
 1.44A 4twdG-5yhbA:
undetectable
4twdH-5yhbA:
undetectable		 4twdG-5yhbA:
21.71
4twdH-5yhbA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 5yhb POLYHEDRIN
(Cypovirus
1) 		4 / 7 ASN A 228
PRO A 227
TRP A  38
TYR A  40
 None
 1.49A 4v2yB-5yhbA:
undetectable		 4v2yB-5yhbA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5yhb POLYHEDRIN
(Cypovirus
1) 		4 / 5 PHE A  65
ARG A 209
ILE A  61
ILE A  51
 None
PD  A 304 ( 2.6A)
None
None
 1.09A 5dzk4-5yhbA:
undetectable
5dzkg-5yhbA:
undetectable
5dzkm-5yhbA:
undetectable
5dzkn-5yhbA:
undetectable		 5dzk4-5yhbA:
2.19
5dzkg-5yhbA:
19.92
5dzkm-5yhbA:
22.43
5dzkn-5yhbA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5yhb POLYHEDRIN
(Cypovirus
1) 		5 / 12 GLY A 181
VAL A 117
VAL A  35
ILE A 109
VAL A  39
 None
 0.96A 5n0sA-5yhbA:
undetectable		 5n0sA-5yhbA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5yhb POLYHEDRIN
(Cypovirus
1) 		5 / 12 GLY A 181
VAL A 117
VAL A  35
ILE A 109
VAL A  39
 None
 0.95A 5n0tA-5yhbA:
undetectable		 5n0tA-5yhbA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5yhb POLYHEDRIN
(Cypovirus
1) 		5 / 12 GLY A 181
VAL A 117
VAL A  35
ILE A 109
VAL A  39
 None
 0.98A 5n0wB-5yhbA:
undetectable		 5n0wB-5yhbA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 5yhb POLYHEDRIN
(Cypovirus
1) 		4 / 7 ASN A 228
PRO A 227
TRP A  38
TYR A  40
 None
 1.45A 5oh1B-5yhbA:
undetectable		 5oh1B-5yhbA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 5yhb POLYHEDRIN
(Cypovirus
1) 		4 / 7 ASN A 228
PRO A 227
TRP A  38
TYR A  40
 None
 1.46A 5oh3B-5yhbA:
undetectable		 5oh3B-5yhbA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5yhb POLYHEDRIN
(Cypovirus
1) 		5 / 12 LEU A 168
ILE A 109
ILE A 225
TYR A 224
LEU A 220
 None
 0.97A 5y2tB-5yhbA:
undetectable		 5y2tB-5yhbA:
undetectable