SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yhq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 5yhq CAPSID PROTEIN VP3
(Enterovirus
A) 		3 / 3 ASN C 211
PHE C 157
VAL C  71
 None
 0.86A 1kijA-5yhqC:
undetectable		 1kijA-5yhqC:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5yhq CAPSID PROTEIN VP1
(Enterovirus
A) 		3 / 3 ASN A 223
TRP A 198
GLN A 219
 None
 1.42A 1xoqA-5yhqA:
undetectable		 1xoqA-5yhqA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_A_CU9A301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5yhq CAPSID PROTEIN VP1
(Enterovirus
A) 		5 / 12 TYR A  80
VAL A  86
MET A 248
ILE A 250
SER A 121
 None
 1.48A 3peoA-5yhqA:
0.0
3peoE-5yhqA:
0.0		 3peoA-5yhqA:
20.58
3peoE-5yhqA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5yhq CAPSID PROTEIN VP3
(Enterovirus
A) 		3 / 3 GLN C 219
GLU C  50
LYS C 114
 None
 1.08A 3su9A-5yhqC:
undetectable		 3su9A-5yhqC:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 5yhq CAPSID PROTEIN VP1
CAPSID PROTEIN VP3
(Enterovirus
A) 		5 / 12 PHE A 130
ALA A 128
ILE C  24
SER C  21
PHE A 228
 None
 1.47A 5uanB-5yhqA:
undetectable		 5uanB-5yhqA:
20.53