SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yi4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5yi4 DISRUPTED IN
SCHIZOPHRENIA 1
HOMOLOG,NUCLEAR
DISTRIBUTION PROTEIN
NUDE-LIKE 1
(Mus
musculus) 		4 / 8 LEU A  32
THR A  57
VAL A  58
LEU A  55
 None
 0.87A 3uniB-5yi4A:
undetectable		 3uniB-5yi4A:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5yi4 DISRUPTED IN
SCHIZOPHRENIA 1
HOMOLOG,NUCLEAR
DISTRIBUTION PROTEIN
NUDE-LIKE 1
(Mus
musculus) 		4 / 5 GLU A  33
GLU A  54
THR A  57
LEU A 120
 None
 1.28A 5hm8G-5yi4A:
undetectable		 5hm8G-5yi4A:
14.00