SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yim'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 ALA A 399
VAL A 401
TRP A 394
 None
 0.73A 1av2A-5yimA:
undetectable
1av2B-5yimA:
undetectable		 1av2A-5yimA:
undetectable
1av2B-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 PHE A 895
LEU A 768
SER A 814
 None
 0.82A 1e7aA-5yimA:
undetectable		 1e7aA-5yimA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 5yim SDEA
(Legionella
pneumophila) 		4 / 7 GLN A1077
PHE A 635
MET A 919
ALA A 921
 None
 1.08A 1linA-5yimA:
undetectable		 1linA-5yimA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5yim SDEA
(Legionella
pneumophila) 		4 / 8 HIS A 392
ASP A 389
THR A 285
PHE A 333
 None
 1.15A 1p7lC-5yimA:
undetectable		 1p7lC-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5yim SDEA
(Legionella
pneumophila) 		4 / 8 HIS A 392
ASP A 389
THR A 285
PHE A 333
 None
 1.14A 1p7lD-5yimA:
undetectable		 1p7lD-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5yim SDEA
(Legionella
pneumophila) 		4 / 8 HIS A 392
ASP A 389
THR A 285
PHE A 333
 None
 1.13A 1rg9A-5yimA:
undetectable		 1rg9A-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5yim SDEA
(Legionella
pneumophila) 		4 / 8 HIS A 392
ASP A 389
THR A 285
PHE A 333
 None
 1.14A 1rg9B-5yimA:
undetectable		 1rg9B-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5yim SDEA
(Legionella
pneumophila) 		4 / 8 HIS A 392
ASP A 389
THR A 285
PHE A 333
 None
 1.14A 1rg9C-5yimA:
undetectable		 1rg9C-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5yim SDEA
(Legionella
pneumophila) 		4 / 8 HIS A 392
ASP A 389
THR A 285
PHE A 333
 None
 1.13A 1rg9D-5yimA:
undetectable		 1rg9D-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 LEU A 571
GLU A 561
ASP A 410
GLY A 278
HIS A 281
 None
 1.44A 1v8bC-5yimA:
undetectable		 1v8bC-5yimA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 ALA A 399
VAL A 401
TRP A 394
 None
 0.72A 1w5uA-5yimA:
undetectable
1w5uB-5yimA:
undetectable		 1w5uA-5yimA:
undetectable
1w5uB-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 TRP A 394
ALA A 399
VAL A 401
 None
 0.82A 1w5uA-5yimA:
undetectable
1w5uB-5yimA:
undetectable		 1w5uA-5yimA:
undetectable
1w5uB-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_B_SAMB417_0
(L-LYSINE
2,3-AMINOMUTASE)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 HIS A 407
THR A 285
ARG A 284
HIS A 277
VAL A 334
 None
 1.35A 2a5hB-5yimA:
undetectable		 2a5hB-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 LEU A 708
LEU A 747
ILE A 740
LEU A 663
THR A 662
 None
 0.97A 2bdmA-5yimA:
undetectable		 2bdmA-5yimA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 5yim SDEA
(Legionella
pneumophila) 		4 / 5 ASP A 356
LEU A 359
LYS A 360
ARG A 355
 None
 1.36A 2gj5A-5yimA:
undetectable		 2gj5A-5yimA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 TRP A 394
ALA A 399
VAL A 401
 None
 0.72A 2izqC-5yimA:
undetectable
2izqD-5yimA:
undetectable		 2izqC-5yimA:
undetectable
2izqD-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5yim SDEA
(Legionella
pneumophila) 		4 / 7 TYR A 246
GLY A 336
ALA A 335
LEU A 252
 None
 0.89A 2wekB-5yimA:
undetectable		 2wekB-5yimA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 SER A 428
VAL A 401
GLN A 405
LEU A 402
ILE A 292
 None
 1.31A 2xrlA-5yimA:
3.8		 2xrlA-5yimA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 THR A1000
SER A 998
PHE A1005
 None
 0.69A 3d4sA-5yimA:
2.3		 3d4sA-5yimA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 ILE A 292
ALA A 437
LEU A 306
VAL A 293
THR A 438
 None
 1.09A 3ix9A-5yimA:
undetectable		 3ix9A-5yimA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 ILE A 292
ALA A 437
LEU A 306
VAL A 293
THR A 438
 None
 1.07A 3ix9B-5yimA:
undetectable		 3ix9B-5yimA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 TRP A 394
ALA A 399
VAL A 401
 None
 0.99A 3l8lA-5yimA:
undetectable
3l8lB-5yimA:
undetectable		 3l8lA-5yimA:
undetectable
3l8lB-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 TRP A 394
ALA A 399
VAL A 401
 None
 0.74A 3l8lC-5yimA:
undetectable
3l8lD-5yimA:
undetectable		 3l8lC-5yimA:
undetectable
3l8lD-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 PRO A 530
SER A 435
ASN A 527
 None
 0.91A 3lslG-5yimA:
undetectable		 3lslG-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 SER A 834
PHE A 895
VAL A 878
LEU A 778
THR A 775
 None
 1.31A 3lxeA-5yimA:
undetectable		 3lxeA-5yimA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 SER A 834
PHE A 895
VAL A 878
LEU A 778
THR A 775
 None
 1.34A 3lxeB-5yimA:
undetectable		 3lxeB-5yimA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 GLU A 388
ALA A 384
PHE A 333
ALA A 335
ASP A 356
 None
 1.07A 3nvkF-5yimA:
3.0
3nvkJ-5yimA:
undetectable		 3nvkF-5yimA:
undetectable
3nvkJ-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 ALA A 299
GLY A 434
SER A 435
LEU A 306
ALA A 787
 None
 1.35A 3ou7C-5yimA:
undetectable		 3ou7C-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 GLU A 419
PHE A 459
GLN A 423
 None
 0.89A 3r55A-5yimA:
undetectable		 3r55A-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 SER A 814
GLY A 815
GLN A 727
 None
 0.36A 3v4tH-5yimA:
undetectable		 3v4tH-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_J_SPMJ202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5yim SDEA
(Legionella
pneumophila) 		4 / 7 MET A 664
GLU A 667
GLU A 671
GLU A 737
 None
 1.34A 4r87J-5yimA:
undetectable
4r87L-5yimA:
undetectable		 4r87J-5yimA:
16.67
4r87L-5yimA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_DIFA601_1
(SERUM ALBUMIN)		 5yim SDEA
(Legionella
pneumophila) 		5 / 9 ASN A 818
ALA A 819
VAL A 865
ARG A 766
GLU A 862
 None
 1.43A 4zbrA-5yimA:
1.5		 4zbrA-5yimA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 ASN A 818
SER A 749
ARG A 595
 None
 0.91A 5b2qA-5yimA:
undetectable		 5b2qA-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 PHE A 965
TYR A 962
PRO A 997
SER A 998
LEU A 946
 None
 1.19A 5hbsA-5yimA:
undetectable		 5hbsA-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 PHE A 965
TYR A 962
PRO A 997
SER A 998
LEU A 946
 None
 1.19A 5ljbA-5yimA:
undetectable		 5ljbA-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 PHE A 965
TYR A 962
PRO A 997
SER A 998
LEU A 946
 None
 1.16A 5ljcA-5yimA:
undetectable		 5ljcA-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 5yim SDEA
(Legionella
pneumophila) 		4 / 4 LEU A 739
MET A 744
ILE A 626
LEU A 613
 None
 1.37A 5nfpA-5yimA:
undetectable		 5nfpA-5yimA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5yim SDEA
(Legionella
pneumophila) 		4 / 8 HIS A 392
ASP A 389
THR A 285
PHE A 333
 None
 1.14A 5t8sB-5yimA:
undetectable		 5t8sB-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5yim SDEA
(Legionella
pneumophila) 		5 / 12 LEU A 867
VAL A 865
SER A 864
MET A 840
LEU A 768
 None
 1.17A 5tudA-5yimA:
4.9		 5tudA-5yimA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5US8_B_ADNB503_1
(ARGININOSUCCINATE
SYNTHASE)		 5yim SDEA
(Legionella
pneumophila) 		5 / 10 ARG A1065
GLU A1067
ARG A1069
GLU A1070
ARG A1066
 None
 1.29A 5us8A-5yimA:
0.0
5us8B-5yimA:
0.0		 5us8A-5yimA:
11.01
5us8B-5yimA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5US8_B_ADNB503_1
(ARGININOSUCCINATE
SYNTHASE)		 5yim SDEA
(Legionella
pneumophila) 		5 / 10 ARG A1069
GLU A1070
ARG A1066
ARG A1065
GLU A1067
 None
 1.34A 5us8A-5yimA:
0.0
5us8B-5yimA:
0.0		 5us8A-5yimA:
11.01
5us8B-5yimA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 5yim SDEA
(Legionella
pneumophila) 		4 / 4 VAL A1029
LEU A1033
LEU A 924
ASP A1050
 None
 1.42A 5xv7A-5yimA:
1.8		 5xv7A-5yimA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5yim SDEA
(Legionella
pneumophila) 		4 / 6 PHE A 448
LEU A 568
LEU A 571
HIS A 575
 None
 0.66A 6e43A-5yimA:
2.3		 6e43A-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5yim SDEA
(Legionella
pneumophila) 		4 / 6 PHE A 448
LEU A 568
LEU A 571
HIS A 575
 None
 0.62A 6e43B-5yimA:
2.7		 6e43B-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5yim SDEA
(Legionella
pneumophila) 		4 / 6 PHE A 448
LEU A 568
LEU A 571
HIS A 575
 None
 0.67A 6e43C-5yimA:
1.9		 6e43C-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5yim SDEA
(Legionella
pneumophila) 		4 / 6 PHE A 448
LEU A 568
LEU A 571
HIS A 575
 None
 0.63A 6e43D-5yimA:
3.0		 6e43D-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 5yim SDEA
(Legionella
pneumophila) 		5 / 11 THR A 821
ALA A 751
THR A 748
THR A 745
ALA A 726
 None
 1.37A 6efnA-5yimA:
undetectable		 6efnA-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 5yim SDEA
(Legionella
pneumophila) 		4 / 5 ARG A1069
ALA A 922
GLN A 611
ILE A 626
 None
 1.47A 6g9bA-5yimA:
undetectable
6g9bB-5yimA:
undetectable		 6g9bA-5yimA:
20.24
6g9bB-5yimA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5yim SDEA
(Legionella
pneumophila) 		3 / 3 HIS A 407
HIS A 277
HIS A 281
 None
 0.70A 6giqa-5yimA:
2.9		 6giqa-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 5yim SDEA
(Legionella
pneumophila) 		4 / 7 GLN A 727
GLY A 815
VAL A 871
SER A 864
 None
 1.05A 6hu9S-5yimA:
undetectable
6hu9q-5yimA:
0.7		 6hu9S-5yimA:
undetectable
6hu9q-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 5yim SDEA
(Legionella
pneumophila) 		4 / 4 ASP A 364
ILE A 370
PRO A 371
LEU A 369
 None
 1.40A 6mkeB-5yimA:
undetectable		 6mkeB-5yimA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 5yim SDEA
(Legionella
pneumophila) 		4 / 4 ASP A 364
ILE A 370
PRO A 371
LEU A 369
 None
 1.41A 6mkeA-5yimA:
undetectable		 6mkeA-5yimA:
19.77