SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yj4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 5yj4 MAJOR PRION PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 137
ASP A 144
ASP A 147
TYR A 150
 None
 1.47A 2lh8A-5yj4A:
9.1		 2lh8A-5yj4A:
82.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 5yj4 MAJOR PRION PROTEIN
(Homo
sapiens) 		4 / 5 ILE A 138
ARG A 136
ARG A 151
ASP A 147
 None
 1.31A 2rhmD-5yj4A:
undetectable		 2rhmD-5yj4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5yj4 MAJOR PRION PROTEIN
(Homo
sapiens) 		3 / 3 MET A 129
ASP A 167
ARG A 228
 None
 1.20A 5z6jA-5yj4A:
undetectable		 5z6jA-5yj4A:
undetectable