SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ykd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A  59
HIS A 183
HIS A 239
ASP A 316
 ZN  A 502 (-3.4A)
ZN  A 501 (-3.3A)
ZN  A 501 (-3.4A)
ZN  A 502 (-2.9A)
 0.42A 1e9yB-5ykdA:
21.8		 1e9yB-5ykdA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 6 HIS A  59
HIS A  61
HIS A 183
HIS A 239
ASP A 316
 ZN  A 502 (-3.4A)
ZN  A 502 (-3.3A)
ZN  A 501 (-3.3A)
ZN  A 501 (-3.4A)
ZN  A 502 (-2.9A)
 0.58A 1fweC-5ykdA:
22.7		 1fweC-5ykdA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 169
THR A 165
ASP A 163
GLU A 219
 None
 1.23A 1mxgA-5ykdA:
4.2		 1mxgA-5ykdA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 262
HIS A 239
PHE A  66
HIS A 183
TYR A 155
 None
ZN  A 501 (-3.4A)
None
ZN  A 501 (-3.3A)
None
 1.29A 1o86A-5ykdA:
undetectable		 1o86A-5ykdA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 12 CYH A 319
THR A  60
ASP A  57
GLY A  82
ALA A 406
 None
 1.28A 1oltA-5ykdA:
2.7		 1oltA-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 11 PHE A 152
SER A 101
LEU A 140
VAL A 146
PHE A 149
 KCX  A 150 ( 4.0A)
None
None
None
None
 1.37A 1q23G-5ykdA:
undetectable		 1q23G-5ykdA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 343
GLY A 441
ILE A  90
GLY A  78
ILE A 342
 None
 1.13A 1q8jB-5ykdA:
2.5		 1q8jB-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 237
ALA A 245
GLU A 248
ARG A 226
LEU A 310
 None
 1.47A 2ocfA-5ykdA:
undetectable		 2ocfA-5ykdA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 11 ASP A 316
HIS A  59
GLU A 185
HIS A 239
SER A 289
 ZN  A 502 (-2.9A)
ZN  A 502 (-3.4A)
None
ZN  A 501 (-3.4A)
None
 1.21A 2q0jB-5ykdA:
undetectable		 2q0jB-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A 372
GLU A 262
ARG A 345
ALA A 314
 None
 1.16A 2v41G-5ykdA:
undetectable
2v41H-5ykdA:
undetectable		 2v41G-5ykdA:
undetectable
2v41H-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 171
GLU A 175
TRP A 129
 None
 1.20A 3hrdA-5ykdA:
undetectable
3hrdE-5ykdA:
undetectable
3hrdF-5ykdA:
undetectable		 3hrdA-5ykdA:
10.59
3hrdE-5ykdA:
10.59
3hrdF-5ykdA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 8 ILE A  31
ALA A 389
LEU A  51
PRO A 380
 None
 0.83A 3ozwA-5ykdA:
undetectable		 3ozwA-5ykdA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 9 ASP A 414
THR A 282
TYR A 286
GLY A 285
LEU A 270
 None
 1.25A 3sfuB-5ykdA:
undetectable		 3sfuB-5ykdA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  51
ILE A   5
ILE A  31
ASP A 390
ALA A 391
 None
 0.88A 3uj7A-5ykdA:
undetectable		 3uj7A-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  51
ILE A   5
ILE A  31
ASP A 390
ALA A 391
 None
 0.89A 3uj7B-5ykdA:
undetectable		 3uj7B-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 264
ASP A 316
GLU A 185
HIS A 183
 None
ZN  A 502 (-2.9A)
None
ZN  A 501 (-3.3A)
 1.26A 4aq7A-5ykdA:
undetectable		 4aq7A-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 6 GLY A  85
GLY A  86
GLU A 343
ILE A 342
 None
 0.94A 4fglD-5ykdA:
undetectable		 4fglD-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A  59
HIS A 183
HIS A 239
ASP A 316
 ZN  A 502 (-3.4A)
ZN  A 501 (-3.3A)
ZN  A 501 (-3.4A)
ZN  A 502 (-2.9A)
 0.41A 4h9mA-5ykdA:
23.5		 4h9mA-5ykdA:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 5 GLU A 185
ARG A 212
PRO A 290
SER A 241
 None
 1.36A 4k17B-5ykdA:
undetectable		 4k17B-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  55
ALA A 373
ALA A 389
ARG A 386
MET A  52
 None
 1.04A 4kicA-5ykdA:
undetectable		 4kicA-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  55
ALA A 373
ALA A 389
ARG A 386
MET A  52
 None
 1.08A 4kicB-5ykdA:
undetectable		 4kicB-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 208
TRP A 280
SER A 289
 None
 1.16A 4lrhD-5ykdA:
undetectable		 4lrhD-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 11 ASP A 344
GLY A 341
ASP A  57
THR A  79
GLY A  78
 None
 0.99A 4qgiA-5ykdA:
undetectable		 4qgiA-5ykdA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 6 HIS A  59
HIS A  61
HIS A 183
HIS A 239
ASP A 316
 ZN  A 502 (-3.4A)
ZN  A 502 (-3.3A)
ZN  A 501 (-3.3A)
ZN  A 501 (-3.4A)
ZN  A 502 (-2.9A)
 0.44A 4ubpC-5ykdA:
22.7		 4ubpC-5ykdA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 7 ASP A  57
ILE A  90
GLY A  78
THR A 315
 None
 1.09A 4zxiA-5ykdA:
undetectable		 4zxiA-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 11 THR A  79
SER A  89
ALA A 117
GLY A 450
ASP A 390
 None
 1.35A 5bxnV-5ykdA:
undetectable
5bxnW-5ykdA:
undetectable		 5bxnV-5ykdA:
15.02
5bxnW-5ykdA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 9 ARG A 345
LEU A 264
GLY A 266
LEU A 268
LEU A 305
 None
 1.16A 5dqfA-5ykdA:
undetectable		 5dqfA-5ykdA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 5 ASP A  57
HIS A  59
GLY A 341
ALA A 340
 None
ZN  A 502 (-3.4A)
None
None
 0.94A 5hwaA-5ykdA:
undetectable		 5hwaA-5ykdA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  80
THR A  79
GLY A  86
GLY A  85
ALA A  84
 None
 0.90A 5lf3K-5ykdA:
undetectable
5lf3L-5ykdA:
undetectable		 5lf3K-5ykdA:
17.65
5lf3L-5ykdA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  80
THR A  79
GLY A  86
GLY A  85
ALA A  84
 None
 0.89A 5lf3Y-5ykdA:
undetectable
5lf3Z-5ykdA:
undetectable		 5lf3Y-5ykdA:
17.65
5lf3Z-5ykdA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  80
THR A  79
GLY A  86
GLY A  85
ALA A  84
 None
 0.92A 5lf7K-5ykdA:
undetectable
5lf7L-5ykdA:
undetectable		 5lf7K-5ykdA:
undetectable
5lf7L-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  80
THR A  79
GLY A  86
GLY A  85
ALA A  84
 None
 0.92A 5lf7Y-5ykdA:
undetectable
5lf7Z-5ykdA:
undetectable		 5lf7Y-5ykdA:
undetectable
5lf7Z-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 253
HIS A 311
LEU A 367
SER A 307
 None
 1.11A 5syjA-5ykdA:
undetectable		 5syjA-5ykdA:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 253
HIS A 311
LEU A 367
SER A 307
 None
 1.12A 5syjB-5ykdA:
undetectable		 5syjB-5ykdA:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A  93
ILE A  95
PHE A 152
PRO A 336
 KCX  A 150 ( 4.0A)
None
KCX  A 150 ( 4.0A)
None
 1.12A 5x23A-5ykdA:
undetectable		 5x23A-5ykdA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 235
PHE A 152
LEU A 264
ILE A 240
HIS A  61
 None
KCX  A 150 ( 4.0A)
None
None
ZN  A 502 (-3.3A)
 1.28A 5y2tA-5ykdA:
undetectable		 5y2tA-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		5 / 12 THR A 370
VAL A 394
GLY A  54
SER A 369
VAL A 354
 None
 1.19A 6a94B-5ykdA:
undetectable		 6a94B-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A  46
LEU A  44
SER A 428
GLN A  49
 None
 1.11A 6ji6A-5ykdA:
undetectable		 6ji6A-5ykdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 5ykd D-HYDANTOINASE/DIHYD
ROPYRIMIDINASE
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 266
HIS A 409
ASN A 416
GLY A 285
 None
 0.96A 6n7fA-5ykdA:
undetectable		 6n7fA-5ykdA:
20.93