SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yl7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 6 HIS A 157
LEU A 165
LEU A 167
PRO A 168
 None
 1.21A 1hz4A-5yl7A:
undetectable		 1hz4A-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		3 / 3 ALA A 254
VAL A 265
TRP A 171
 None
 0.87A 1jo3A-5yl7A:
undetectable		 1jo3A-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		3 / 3 ALA A 254
VAL A 265
TRP A 171
 None
 0.87A 1jo3B-5yl7A:
undetectable		 1jo3B-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 8 ASN A 197
GLY A 250
THR A 405
GLY A 261
 None
None
None
CA  A 801 ( 4.3A)
 0.73A 1jr1B-5yl7A:
undetectable		 1jr1B-5yl7A:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 6 TRP A 171
HIS A 430
TYR A 158
GLY A 164
 None
 1.42A 1mxdA-5yl7A:
2.2		 1mxdA-5yl7A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		3 / 3 ALA A 254
VAL A 265
TRP A 171
 None
 0.73A 1nt6A-5yl7A:
undetectable		 1nt6A-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		3 / 3 ALA A 254
VAL A 265
TRP A 171
 None
 0.73A 1nt6B-5yl7A:
undetectable		 1nt6B-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 LEU A 454
ALA A 481
ALA A 478
VAL A 431
LEU A 165
 None
 1.32A 1rbpA-5yl7A:
undetectable		 1rbpA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 7 GLY A 372
ARG A 459
VAL A 368
PRO A 389
 None
 1.02A 1rxcD-5yl7A:
undetectable		 1rxcD-5yl7A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 7 GLY A 372
ARG A 459
VAL A 368
PRO A 389
 None
 1.05A 1rxcF-5yl7A:
undetectable		 1rxcF-5yl7A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 7 GLY A 372
ARG A 459
VAL A 368
PRO A 389
 None
 0.98A 1rxcL-5yl7A:
undetectable		 1rxcL-5yl7A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 6 LEU A 316
GLY A 317
ASN A 355
ILE A 287
 None
 0.82A 1xf1B-5yl7A:
14.5		 1xf1B-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 5 GLY A 423
GLN A 422
VAL A 402
SER A 367
 None
 1.34A 1zzqB-5yl7A:
undetectable		 1zzqB-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 THR A 284
GLY A 318
GLY A 317
GLY A 282
ASP A 349
 None
 1.06A 2b25A-5yl7A:
undetectable		 2b25A-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 7 ARG A 275
ASN A 212
ASP A 213
GLY A 281
 None
None
CA  A 802 ( 2.2A)
None
 1.02A 2f6dA-5yl7A:
undetectable		 2f6dA-5yl7A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 ILE A 287
ALA A 329
THR A 338
VAL A 181
LEU A 184
 None
 1.21A 2rctA-5yl7A:
undetectable		 2rctA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 4 ARG A 370
GLY A 163
GLU A 160
SER A 378
 None
 1.33A 2xctS-5yl7A:
undetectable
2xctU-5yl7A:
0.9		 2xctS-5yl7A:
8.39
2xctU-5yl7A:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_C_TMQC613_1
(DHFR-TS)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 VAL A 248
ALA A 428
ILE A 342
ILE A 287
LEU A 277
 None
 1.03A 3clbC-5yl7A:
undetectable		 3clbC-5yl7A:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_C_TMQC613_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 11 VAL A 248
ALA A 428
ILE A 342
ILE A 287
LEU A 277
 None
 1.03A 3hbbC-5yl7A:
undetectable		 3hbbC-5yl7A:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 8 TYR A 158
VAL A 265
VAL A 473
GLY A 433
 None
 0.95A 3hjoA-5yl7A:
undetectable		 3hjoA-5yl7A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 GLY A 261
GLY A 264
GLN A 155
ALA A 254
ASN A 197
 CA  A 801 ( 4.3A)
None
None
None
None
 1.05A 3kkzB-5yl7A:
undetectable		 3kkzB-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 10 TYR A 158
VAL A 265
GLY A 264
VAL A 473
GLY A 433
 None
 1.07A 3km6A-5yl7A:
undetectable		 3km6A-5yl7A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 9 TYR A 158
VAL A 265
GLY A 264
VAL A 473
GLY A 433
 None
 1.07A 3kmoA-5yl7A:
undetectable		 3kmoA-5yl7A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 GLY A 176
ASN A 197
VAL A 434
TRP A 171
THR A 173
 None
 0.98A 3p2kB-5yl7A:
2.0		 3p2kB-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 5 SER A 219
PRO A 273
TYR A 188
VAL A 274
 None
 1.36A 3sufC-5yl7A:
undetectable		 3sufC-5yl7A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		3 / 3 PRO A 150
ASP A 149
GLU A 260
 None
CA  A 801 (-3.3A)
None
 0.66A 3v4tC-5yl7A:
undetectable		 3v4tC-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 SER A 378
ARG A 374
VAL A 431
HIS A 430
LEU A 165
 None
 1.45A 3vt7A-5yl7A:
undetectable		 3vt7A-5yl7A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 7 GLY A 372
ARG A 459
VAL A 368
PRO A 389
 None
 1.04A 4e1vB-5yl7A:
undetectable		 4e1vB-5yl7A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 8 ASN A 197
GLY A 250
THR A 405
GLY A 261
 None
None
None
CA  A 801 ( 4.3A)
 0.64A 4fo4B-5yl7A:
undetectable		 4fo4B-5yl7A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 7 TRP A 243
THR A 246
SER A 417
HIS A 191
 None
 1.25A 4o4dA-5yl7A:
undetectable		 4o4dA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 ALA A 263
GLY A 264
ASN A 197
GLY A 261
ASN A 257
 None
None
None
CA  A 801 ( 4.3A)
None
 1.24A 4obwD-5yl7A:
2.2		 4obwD-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 LEU A 165
VAL A 434
THR A 251
HIS A 247
GLY A 245
 None
 1.25A 4q15A-5yl7A:
2.0		 4q15A-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 9 ALA A 343
ALA A 428
GLY A 318
GLY A 317
ASP A 185
 None
 1.15A 4qwuK-5yl7A:
undetectable
4qwuL-5yl7A:
undetectable		 4qwuK-5yl7A:
16.11
4qwuL-5yl7A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 6 ASP A 193
ALA A 263
THR A 405
TYR A 418
 CA  A 801 (-2.2A)
None
None
None
 1.43A 4w5qA-5yl7A:
2.6		 4w5qA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 6 ASP A 193
ALA A 263
THR A 405
TYR A 418
 CA  A 801 (-2.2A)
None
None
None
 1.41A 4w5rA-5yl7A:
2.6		 4w5rA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 6 ASP A 193
ALA A 263
THR A 405
TYR A 418
 CA  A 801 (-2.2A)
None
None
None
 1.45A 4w5tA-5yl7A:
undetectable		 4w5tA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 6 ASP A 193
ALA A 263
THR A 405
TYR A 418
 CA  A 801 (-2.2A)
None
None
None
 1.44A 4z4cA-5yl7A:
2.8		 4z4cA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 6 ASP A 193
ALA A 263
THR A 405
TYR A 418
 CA  A 801 (-2.2A)
None
None
None
 1.43A 4z4fA-5yl7A:
undetectable		 4z4fA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 5 ASP A 193
ALA A 263
THR A 405
TYR A 418
 CA  A 801 (-2.2A)
None
None
None
 1.43A 4z4gA-5yl7A:
2.2		 4z4gA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 6 ASP A 193
ALA A 263
THR A 405
TYR A 418
 CA  A 801 (-2.2A)
None
None
None
 1.46A 4z4iA-5yl7A:
2.6		 4z4iA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 7 ASN A 257
PRO A 147
PHE A 152
TYR A 418
 None
 1.15A 5amhA-5yl7A:
undetectable		 5amhA-5yl7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 5 SER A 378
ARG A 370
GLY A 163
GLU A 160
 None
 0.84A 5cdqA-5yl7A:
undetectable
5cdqB-5yl7A:
undetectable
5cdqC-5yl7A:
undetectable		 5cdqA-5yl7A:
10.78
5cdqB-5yl7A:
15.14
5cdqC-5yl7A:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 5 SER A 378
ARG A 370
GLY A 163
GLU A 160
 None
 0.84A 5cdqR-5yl7A:
undetectable
5cdqS-5yl7A:
undetectable
5cdqT-5yl7A:
undetectable		 5cdqR-5yl7A:
10.78
5cdqS-5yl7A:
15.14
5cdqT-5yl7A:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 4 LEU A 437
ILE A 438
GLY A 433
ILE A 450
 None
 0.87A 5dzk3-5yl7A:
undetectable
5dzkm-5yl7A:
2.6		 5dzk3-5yl7A:
undetectable
5dzkm-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 5 ILE A 438
GLY A 433
ILE A 450
LEU A 437
 None
 0.88A 5dzki-5yl7A:
undetectable
5dzkj-5yl7A:
undetectable
5dzkx-5yl7A:
undetectable		 5dzki-5yl7A:
undetectable
5dzkj-5yl7A:
undetectable
5dzkx-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 5 ILE A 438
GLY A 433
ILE A 450
LEU A 437
 None
 0.93A 5dzkd-5yl7A:
undetectable
5dzkk-5yl7A:
undetectable
5dzky-5yl7A:
undetectable		 5dzkd-5yl7A:
undetectable
5dzkk-5yl7A:
undetectable
5dzky-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		4 / 7 VAL A 271
ALA A 269
GLY A 433
VAL A 252
 None
 0.77A 5fpdA-5yl7A:
undetectable		 5fpdA-5yl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 VAL A 181
ALA A 343
VAL A 248
GLY A 250
ALA A 249
 None
 1.07A 5kirA-5yl7A:
undetectable		 5kirA-5yl7A:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 VAL A 181
ALA A 343
VAL A 248
GLY A 250
ALA A 249
 None
 1.07A 5kirB-5yl7A:
undetectable		 5kirB-5yl7A:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 9 ASP A 226
GLY A 187
GLY A 245
ALA A 249
VAL A 248
 None
 1.45A 5v3cA-5yl7A:
undetectable		 5v3cA-5yl7A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 9 VAL A 252
HIS A 430
GLY A 433
ILE A 291
ASP A 185
 None
 1.08A 6c2mC-5yl7A:
undetectable		 6c2mC-5yl7A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 VAL A 181
ASP A 310
LEU A 167
LEU A 165
LEU A 454
 None
 1.00A 6ew0B-5yl7A:
undetectable		 6ew0B-5yl7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 VAL A 181
ASP A 310
LEU A 167
LEU A 165
LEU A 454
 None
 1.00A 6ew0D-5yl7A:
undetectable		 6ew0D-5yl7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 VAL A 181
ASP A 310
LEU A 167
LEU A 165
LEU A 454
 None
 1.00A 6ew0F-5yl7A:
undetectable		 6ew0F-5yl7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 VAL A 181
ASP A 310
LEU A 167
LEU A 165
LEU A 454
 None
 1.00A 6ew0G-5yl7A:
undetectable		 6ew0G-5yl7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 VAL A 181
ASP A 310
LEU A 167
LEU A 165
LEU A 454
 None
 1.00A 6ew0H-5yl7A:
undetectable		 6ew0H-5yl7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717
(Pseudoalteromona
s
arctica) 		5 / 12 VAL A 181
ASP A 310
LEU A 167
LEU A 165
LEU A 454
 None
 1.00A 6ew0I-5yl7A:
undetectable		 6ew0I-5yl7A:
20.24