SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ylv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		4 / 5 VAL B  82
GLY B 280
TYR B 278
ASP B 276
 None
 1.30A 3w9tA-5ylvB:
undetectable		 3w9tA-5ylvB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		4 / 5 VAL B  82
GLY B 280
TYR B 278
ASP B 276
 None
 1.30A 3w9tB-5ylvB:
undetectable		 3w9tB-5ylvB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		4 / 5 VAL B  82
GLY B 280
TYR B 278
ASP B 276
 None
 1.30A 3w9tC-5ylvB:
undetectable		 3w9tC-5ylvB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		4 / 5 VAL B  82
GLY B 280
TYR B 278
ASP B 276
 None
 1.31A 3w9tD-5ylvB:
undetectable		 3w9tD-5ylvB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		4 / 5 VAL B  82
GLY B 280
TYR B 278
ASP B 276
 None
 1.30A 3w9tE-5ylvB:
undetectable		 3w9tE-5ylvB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		4 / 5 VAL B  82
GLY B 280
TYR B 278
ASP B 276
 None
 1.31A 3w9tF-5ylvB:
undetectable		 3w9tF-5ylvB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		4 / 5 VAL B  82
GLY B 280
TYR B 278
ASP B 276
 None
 1.30A 3w9tG-5ylvB:
undetectable		 3w9tG-5ylvB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		3 / 3 LYS B 235
LYS B 234
PRO B 238
 None
 1.17A 4dv1L-5ylvB:
undetectable		 4dv1L-5ylvB:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		4 / 4 GLY B 171
LEU B 117
PHE B 116
ILE B 180
 None
 0.92A 4xv2A-5ylvB:
undetectable		 4xv2A-5ylvB:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		5 / 12 VAL B 259
GLY B 171
ALA B 247
ALA B 246
VAL B 245
 None
 0.81A 6c2mC-5ylvB:
undetectable		 6c2mC-5ylvB:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA
(Sus
scrofa) 		4 / 4 LEU B 113
ASP B  87
PRO B  86
ARG B  85
 None
 1.25A 6fgdA-5ylvB:
undetectable		 6fgdA-5ylvB:
undetectable