SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ylz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IE4_A_T44A128_1 (TRANSTHYRETIN)	5ylz	PRE-MRNA-SPLICING FACTOR CEF1 (Saccharomyces cerevisiae)	5 / 10	GLU J 68 ALA J 71 LEU J 76 LEU J 105 GLU J 64	None	1.31A	1ie4A-5ylzJ: undetectable 1ie4C-5ylzJ: undetectable	1ie4A-5ylzJ: undetectable 1ie4C-5ylzJ: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T9W_A_NFNA6002_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	5ylz	PRE-MRNA-SPLICING FACTOR CEF1 (Saccharomyces cerevisiae)	4 / 7	GLN J 96 ALA J 88 PHE J 62 GLU J 54	None	1.36A	1t9wA-5ylzJ: undetectable	1t9wA-5ylzJ: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z0A_A_GLYA73_0 (NONSTRUCTURAL PROTEIN 1)	5ylz	PRE-MRNA-SPLICING FACTOR CEF1 (Saccharomyces cerevisiae)	4 / 5	GLN J 163 ALA J 167 ILE J 171 ARG J 174	None C D 85 ( 3.4A) None G D 86 ( 4.1A)	1.03A	2z0aA-5ylzJ: undetectable	2z0aA-5ylzJ: undetectable