SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5yq0 COFJ
(Escherichia
coli) 		3 / 3 GLU A 158
TYR A  86
PHE A 160
 None
 0.94A 1eqbB-5yq0A:
undetectable		 1eqbB-5yq0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5yq0 COFJ
(Escherichia
coli) 		3 / 3 GLU A 158
TYR A  86
PHE A 160
 None
 0.94A 1eqbA-5yq0A:
undetectable		 1eqbA-5yq0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5yq0 COFJ
(Escherichia
coli) 		3 / 3 GLU A 158
TYR A  86
PHE A 160
 None
 0.94A 1eqbD-5yq0A:
undetectable		 1eqbD-5yq0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5yq0 COFJ
(Escherichia
coli) 		3 / 3 GLU A 158
TYR A  86
PHE A 160
 None
 0.95A 1eqbC-5yq0A:
undetectable		 1eqbC-5yq0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 5yq0 COFJ
(Escherichia
coli) 		5 / 12 PHE A 154
ASN A 130
GLY A 151
ALA A 220
ASN A 228
 None
 1.21A 3v3oB-5yq0A:
undetectable		 3v3oB-5yq0A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5yq0 COFJ
(Escherichia
coli) 		3 / 3 ASN A 240
TRP A 244
ASP A  72
 None
 0.94A 4a7tA-5yq0A:
undetectable
4a7tF-5yq0A:
1.4		 4a7tA-5yq0A:
17.29
4a7tF-5yq0A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 5yq0 COFJ
(Escherichia
coli) 		4 / 8 TRP A 121
PRO A  93
GLY A 151
PRO A 150
 None
 1.16A 5kf8A-5yq0A:
undetectable		 5kf8A-5yq0A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 5yq0 COFJ
(Escherichia
coli) 		5 / 12 TRP A 244
ALA A  78
GLY A  59
SER A 300
ASP A 206
 None
 1.23A 6clxA-5yq0A:
undetectable		 6clxA-5yq0A:
undetectable