SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 12 LEU M 607
HIS M 487
LEU M 491
HIS M 515
PHE M 519
 BCL  M 702 (-4.5A)
None
None
None
BCL  M 702 ( 4.4A)
 1.35A 1d4fC-5yq7M:
undetectable		 1d4fC-5yq7M:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		3 / 3 LEU L 226
HIS L 264
ILE L 263
 None
FE  L1005 (-4.4A)
MQE  L1004 ( 4.5A)
 0.60A 1s9pB-5yq7L:
undetectable		 1s9pB-5yq7L:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 7 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.95A 2v2gA-5yq7M:
undetectable
2v2gB-5yq7M:
undetectable		 2v2gA-5yq7M:
undetectable
2v2gB-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 7 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.91A 2v2gA-5yq7M:
undetectable
2v2gB-5yq7M:
undetectable		 2v2gA-5yq7M:
undetectable
2v2gB-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 7 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.89A 2v2gC-5yq7M:
undetectable
2v2gD-5yq7M:
undetectable		 2v2gC-5yq7M:
undetectable
2v2gD-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 7 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.92A 2v2gC-5yq7M:
undetectable
2v2gD-5yq7M:
undetectable		 2v2gC-5yq7M:
undetectable
2v2gD-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 8 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.95A 2v32A-5yq7M:
undetectable
2v32B-5yq7M:
undetectable		 2v32A-5yq7M:
undetectable
2v32B-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 8 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.89A 2v32C-5yq7M:
undetectable
2v32D-5yq7M:
undetectable		 2v32C-5yq7M:
undetectable
2v32D-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 8 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.93A 2v32C-5yq7M:
undetectable
2v32D-5yq7M:
undetectable		 2v32C-5yq7M:
undetectable
2v32D-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 8 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.87A 2v41C-5yq7M:
undetectable
2v41D-5yq7M:
undetectable		 2v41C-5yq7M:
undetectable
2v41D-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 8 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.88A 2v41C-5yq7M:
undetectable
2v41D-5yq7M:
undetectable		 2v41C-5yq7M:
undetectable
2v41D-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 7 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.89A 2v41E-5yq7M:
undetectable
2v41F-5yq7M:
undetectable		 2v41E-5yq7M:
undetectable
2v41F-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 7 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.89A 2v41E-5yq7M:
undetectable
2v41F-5yq7M:
undetectable		 2v41E-5yq7M:
undetectable
2v41F-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 8 THR M 422
PRO M 421
SER M 495
GLU C 221
 None
 0.89A 2v41G-5yq7M:
undetectable
2v41H-5yq7M:
undetectable		 2v41G-5yq7M:
undetectable
2v41H-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 542
HIS L 229
HIS L 264
HIS M 589
 FE  L1005 ( 3.0A)
FE  L1005 (-3.1A)
FE  L1005 (-4.4A)
FE  L1005 (-3.2A)
 1.06A 2wkoA-5yq7M:
undetectable		 2wkoA-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 11 THR M 545
ILE M 546
GLY M 543
HIS M 589
ILE M 588
 MQE  M 701 (-4.0A)
None
None
FE  L1005 (-3.2A)
MQE  M 701 (-4.4A)
 1.29A 2y7kA-5yq7M:
undetectable		 2y7kA-5yq7M:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 12 THR M 545
ILE M 546
GLY M 543
HIS M 589
ILE M 588
 MQE  M 701 (-4.0A)
None
None
FE  L1005 (-3.2A)
MQE  M 701 (-4.4A)
 1.20A 2y7kC-5yq7M:
undetectable		 2y7kC-5yq7M:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 10 THR M 545
ILE M 546
GLY M 543
HIS M 589
ILE M 588
 MQE  M 701 (-4.0A)
None
None
FE  L1005 (-3.2A)
MQE  M 701 (-4.4A)
 1.28A 2y7pA-5yq7M:
undetectable		 2y7pA-5yq7M:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 7 THR M 545
ILE M 546
GLY M 543
HIS M 589
 MQE  M 701 (-4.0A)
None
None
FE  L1005 (-3.2A)
 0.83A 2y7wC-5yq7M:
undetectable		 2y7wC-5yq7M:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 7 ILE M 505
LEU M 489
PHE M 486
LEU M 479
 BPH  M 703 (-4.1A)
None
None
BCL  M 702 (-4.6A)
 0.87A 3adxA-5yq7M:
undetectable		 3adxA-5yq7M:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		3 / 3 THR C 212
SER C 251
LYS C 257
 HEM  C 503 (-3.0A)
None
None
 1.15A 3aocC-5yq7C:
undetectable		 3aocC-5yq7C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 12 PHE M 481
LEU M 485
HIS M 500
SER M 389
SER M 448
 None
 1.49A 3apvA-5yq7M:
undetectable		 3apvA-5yq7M:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 12 SER M 554
GLU M 557
ILE M 546
LEU M 539
GLY L 262
 None
FE  L1005 (-1.7A)
None
None
None
 1.01A 3k2hA-5yq7M:
undetectable		 3k2hA-5yq7M:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 12 SER M 554
GLU M 557
ILE M 546
LEU M 539
GLY L 262
 None
FE  L1005 (-1.7A)
None
None
None
 1.01A 3k2hB-5yq7M:
undetectable		 3k2hB-5yq7M:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		3 / 3 ASN L 240
ASN L 245
GLU L 236
 None
 0.89A 3kpdC-5yq7L:
undetectable		 3kpdC-5yq7L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		3 / 3 ASN L 240
ASN L 245
GLU L 236
 None
 0.90A 3kpdB-5yq7L:
undetectable		 3kpdB-5yq7L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 12 SER M 554
GLU M 557
ILE M 546
LEU M 539
GLY L 262
 None
FE  L1005 (-1.7A)
None
None
None
 1.12A 4foxA-5yq7M:
undetectable		 4foxA-5yq7M:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 12 SER M 554
GLU M 557
ILE M 546
LEU M 539
GLY L 262
 None
FE  L1005 (-1.7A)
None
None
None
 1.12A 4foxB-5yq7M:
undetectable		 4foxB-5yq7M:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 12 SER M 554
GLU M 557
ILE M 546
LEU M 539
GLY L 262
 None
FE  L1005 (-1.7A)
None
None
None
 1.14A 4foxG-5yq7M:
undetectable		 4foxG-5yq7M:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 7 ILE M 588
HIS M 542
LEU M 538
GLY L 230
 MQE  M 701 (-4.4A)
FE  L1005 ( 3.0A)
MQE  M 701 ( 4.9A)
None
 0.90A 4z69A-5yq7M:
2.9		 4z69A-5yq7M:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		3 / 3 TYR L 204
TYR M 511
GLN C 226
 HEM  C 503 (-4.4A)
None
HEM  C 503 ( 3.8A)
 1.07A 5jsdA-5yq7L:
undetectable
5jsdB-5yq7L:
undetectable		 5jsdA-5yq7L:
8.90
5jsdB-5yq7L:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		3 / 3 TYR L 204
TYR M 511
GLN C 226
 HEM  C 503 (-4.4A)
None
HEM  C 503 ( 3.8A)
 1.06A 5jsdB-5yq7L:
undetectable
5jsdC-5yq7L:
undetectable		 5jsdB-5yq7L:
8.90
5jsdC-5yq7L:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 5 ILE L 105
LEU L  82
GLY L  83
PHE L  86
 None
None
BPH  L1003 ( 4.5A)
None
 0.57A 5kmdC-5yq7L:
3.4
5kmdD-5yq7L:
2.4		 5kmdC-5yq7L:
16.12
5kmdD-5yq7L:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 6 THR M 509
TYR M 511
TYR L 204
PHE C 227
 BPH  M 703 ( 4.7A)
None
HEM  C 503 (-4.4A)
None
 1.32A 5lrbA-5yq7M:
undetectable		 5lrbA-5yq7M:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 5yq7 CYTOCHROME SUBUNIT
OF PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 6 THR M 509
TYR M 511
TYR L 208
PHE C 227
 BPH  M 703 ( 4.7A)
None
None
None
 1.26A 5lrbA-5yq7M:
undetectable		 5lrbA-5yq7M:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 8 HIS L 264
HIS L 229
LEU L 226
GLY L 230
 FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
None
None
 0.80A 5m8rC-5yq7L:
undetectable		 5m8rC-5yq7L:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 8 HIS M 589
HIS M 542
LEU M 539
GLY M 543
 FE  L1005 (-3.2A)
FE  L1005 ( 3.0A)
None
None
 0.74A 5m8rC-5yq7M:
undetectable		 5m8rC-5yq7M:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.00A 5mhwA-5yq7M:
undetectable		 5mhwA-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.00A 5mhxA-5yq7M:
undetectable		 5mhxA-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.00A 5mhyA-5yq7M:
undetectable		 5mhyA-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.01A 5mhzA-5yq7M:
undetectable		 5mhzA-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.01A 5mi1A-5yq7M:
undetectable		 5mi1A-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.01A 5mi2A-5yq7M:
undetectable		 5mi2A-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.02A 5miaA-5yq7M:
undetectable		 5miaA-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.02A 5mibA-5yq7M:
undetectable		 5mibA-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.01A 5micA-5yq7M:
undetectable		 5micA-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.01A 5midA-5yq7M:
undetectable		 5midA-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		4 / 4 HIS M 589
HIS L 264
HIS L 229
HIS M 542
 FE  L1005 (-3.2A)
FE  L1005 (-4.4A)
FE  L1005 (-3.1A)
FE  L1005 ( 3.0A)
 1.02A 5mieA-5yq7M:
undetectable		 5mieA-5yq7M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		5 / 12 HIS L 264
LEU M 539
ILE L 263
HIS L 229
HIS M 589
 FE  L1005 (-4.4A)
None
MQE  L1004 ( 4.5A)
FE  L1005 (-3.1A)
FE  L1005 (-3.2A)
 1.14A 6n91A-5yq7L:
undetectable		 6n91A-5yq7L:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		5 / 12 HIS L 264
LEU M 539
ILE L 263
HIS L 229
HIS M 589
 FE  L1005 (-4.4A)
None
MQE  L1004 ( 4.5A)
FE  L1005 (-3.1A)
FE  L1005 (-3.2A)
 1.15A 6n91B-5yq7L:
undetectable		 6n91B-5yq7L:
19.54