SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ys6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 5ys6 PRV GLYCOPROTEN B
(Suid
alphaherpesvirus
1) 		4 / 8 TYR A 293
PHE A 311
THR A 371
LEU A 421
 None
 0.93A 1ea1A-5ys6A:
undetectable		 1ea1A-5ys6A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5ys6 PRV GLYCOPROTEN B
(Suid
alphaherpesvirus
1) 		4 / 5 PHE A 407
SER A 528
THR A 526
PHE A 531
 None
 1.30A 1icuC-5ys6A:
undetectable
1icuD-5ys6A:
undetectable		 1icuC-5ys6A:
17.79
1icuD-5ys6A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5ys6 PRV GLYCOPROTEN B
(Suid
alphaherpesvirus
1) 		4 / 8 ASN A 354
ARG A 373
TYR A 325
SER A 309
 None
 1.15A 2zw9B-5ys6A:
undetectable		 2zw9B-5ys6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 5ys6 PRV GLYCOPROTEN B
(Suid
alphaherpesvirus
1) 		4 / 5 ILE A 598
SER A 599
PRO A 130
PRO A 128
 None
 1.03A 3bjwC-5ys6A:
undetectable		 3bjwC-5ys6A:
18.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5ys6 PRV GLYCOPROTEN B
(Suid
alphaherpesvirus
1) 		4 / 7 VAL A 203
ILE A 174
TYR A 175
ILE A 283
 None
 1.05A 3hgxA-5ys6A:
undetectable		 3hgxA-5ys6A:
30.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5ys6 PRV GLYCOPROTEN B
(Suid
alphaherpesvirus
1) 		4 / 8 GLY A 606
LEU A 643
VAL A 610
TYR A 609
 None
 0.87A 4fgzB-5ys6A:
undetectable		 4fgzB-5ys6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5ys6 PRV GLYCOPROTEN B
(Suid
alphaherpesvirus
1) 		3 / 3 TYR A 224
PHE A 197
ARG A 226
 None
 1.21A 4g19D-5ys6A:
undetectable		 4g19D-5ys6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5ys6 PRV GLYCOPROTEN B
(Suid
alphaherpesvirus
1) 		4 / 8 LEU A 414
VAL A 454
VAL A 462
PHE A 161
 None
 0.51A 5y9mX-5ys6A:
undetectable		 5y9mX-5ys6A:
21.69