SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ys9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 1.07A 1c8lA-5ys9A:
undetectable		 1c8lA-5ys9A:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		5 / 12 ILE A  38
PHE A  36
LEU A 359
LEU A 639
PHE A 314
 None
 1.01A 1dtlA-5ys9A:
undetectable		 1dtlA-5ys9A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 7 ILE A 644
ARG A 319
PHE A 320
PHE A 441
 None
 1.23A 1e72M-5ys9A:
undetectable		 1e72M-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 1.03A 1gfzA-5ys9A:
undetectable		 1gfzA-5ys9A:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.99A 1l5qA-5ys9A:
undetectable		 1l5qA-5ys9A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.99A 1l5qB-5ys9A:
undetectable		 1l5qB-5ys9A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.97A 1l7xA-5ys9A:
undetectable		 1l7xA-5ys9A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.99A 1l7xB-5ys9A:
undetectable		 1l7xB-5ys9A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		3 / 3 ARG A 256
ILE A 423
TRP A 448
 None
 1.18A 1m8eB-5ys9A:
undetectable		 1m8eB-5ys9A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		5 / 12 ILE A 189
LEU A 218
ALA A 178
PHE A 229
THR A 184
 None
 1.21A 1og5B-5ys9A:
undetectable		 1og5B-5ys9A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		3 / 3 ASP A  40
THR A  42
GLU A  56
 None
 0.83A 1pj7A-5ys9A:
undetectable		 1pj7A-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 585
MET A  41
THR A  42
LEU A  45
 None
 0.86A 1v54A-5ys9A:
3.0
1v54J-5ys9A:
undetectable		 1v54A-5ys9A:
undetectable
1v54J-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 585
MET A  41
THR A  42
LEU A  45
 None
 0.84A 2dyrA-5ys9A:
2.4
2dyrJ-5ys9A:
undetectable		 2dyrA-5ys9A:
undetectable
2dyrJ-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.08A 2dysA-5ys9A:
undetectable
2dysC-5ys9A:
3.3		 2dysA-5ys9A:
undetectable
2dysC-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 585
MET A  41
THR A  42
LEU A  45
 None
 0.86A 2dysA-5ys9A:
1.9
2dysJ-5ys9A:
undetectable		 2dysA-5ys9A:
undetectable
2dysJ-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 585
MET A  41
THR A  42
LEU A  45
 None
 0.87A 2dysN-5ys9A:
3.0
2dysW-5ys9A:
undetectable		 2dysN-5ys9A:
undetectable
2dysW-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 585
MET A  41
THR A  42
LEU A  45
 None
 0.90A 2eijA-5ys9A:
3.0
2eijJ-5ys9A:
undetectable		 2eijA-5ys9A:
undetectable
2eijJ-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 7 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.08A 2eikA-5ys9A:
undetectable
2eikC-5ys9A:
2.5		 2eikA-5ys9A:
undetectable
2eikC-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 7 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.08A 2eilA-5ys9A:
2.4
2eilC-5ys9A:
3.3		 2eilA-5ys9A:
undetectable
2eilC-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 585
MET A  41
THR A  42
LEU A  45
 None
 0.83A 2eilA-5ys9A:
2.4
2eilJ-5ys9A:
undetectable		 2eilA-5ys9A:
undetectable
2eilJ-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.05A 2eimA-5ys9A:
0.7
2eimC-5ys9A:
3.3		 2eimA-5ys9A:
undetectable
2eimC-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.07A 2eimN-5ys9A:
undetectable
2eimP-5ys9A:
3.3		 2eimN-5ys9A:
undetectable
2eimP-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.08A 2einA-5ys9A:
2.4
2einC-5ys9A:
3.2		 2einA-5ys9A:
undetectable
2einC-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.06A 2einN-5ys9A:
2.1
2einP-5ys9A:
3.2		 2einN-5ys9A:
undetectable
2einP-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 110
LEU A 639
MET A  59
GLU A  56
 None
 1.27A 2kuhA-5ys9A:
undetectable		 2kuhA-5ys9A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		6 / 12 GLN A 109
ALA A 311
VAL A 316
GLY A 112
SER A 108
ILE A 259
 None
 1.28A 2v0zO-5ys9A:
undetectable		 2v0zO-5ys9A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		3 / 3 ARG A 119
GLY A 117
SER A 207
 None
 0.50A 2xctB-5ys9A:
undetectable		 2xctB-5ys9A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		5 / 11 ALA A 446
ALA A 444
GLY A 442
PHE A 320
ARG A 319
 None
 1.41A 2xfsB-5ys9A:
undetectable		 2xfsB-5ys9A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 585
MET A  41
THR A  42
LEU A  45
 None
 0.85A 2zxwA-5ys9A:
2.3
2zxwJ-5ys9A:
undetectable		 2zxwA-5ys9A:
undetectable
2zxwJ-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 7 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.10A 3abkN-5ys9A:
undetectable
3abkP-5ys9A:
3.3		 3abkN-5ys9A:
undetectable
3abkP-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 585
MET A  41
THR A  42
LEU A  45
 None
 0.86A 3abmA-5ys9A:
2.5
3abmJ-5ys9A:
undetectable		 3abmA-5ys9A:
undetectable
3abmJ-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 7 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.07A 3ag3N-5ys9A:
undetectable
3ag3P-5ys9A:
3.3		 3ag3N-5ys9A:
undetectable
3ag3P-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 585
MET A  41
THR A  42
LEU A  45
 None
 0.91A 3asnA-5ys9A:
3.0
3asnJ-5ys9A:
undetectable		 3asnA-5ys9A:
undetectable
3asnJ-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 LEU A 585
MET A  41
THR A  42
LEU A  45
 None
 0.88A 3asoA-5ys9A:
1.9
3asoJ-5ys9A:
undetectable		 3asoA-5ys9A:
undetectable
3asoJ-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 5 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.98A 3bcrA-5ys9A:
2.0		 3bcrA-5ys9A:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.99A 3dd1A-5ys9A:
undetectable		 3dd1A-5ys9A:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 1.01A 3dd1B-5ys9A:
undetectable		 3dd1B-5ys9A:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 1.00A 3ddsA-5ys9A:
undetectable		 3ddsA-5ys9A:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.99A 3ddsB-5ys9A:
undetectable		 3ddsB-5ys9A:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.97A 3ddwA-5ys9A:
undetectable		 3ddwA-5ys9A:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.98A 3ddwB-5ys9A:
undetectable		 3ddwB-5ys9A:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		3 / 3 ARG A 256
ILE A 423
TRP A 448
 None
 1.18A 3e6tB-5ys9A:
0.0		 3e6tB-5ys9A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		5 / 10 ILE A 345
GLY A 434
PRO A 647
VAL A 655
LEU A 355
 None
 1.39A 3elzB-5ys9A:
undetectable		 3elzB-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 5 ILE A 522
THR A 558
PHE A 414
PHE A 551
 None
 1.25A 3em0A-5ys9A:
undetectable		 3em0A-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		5 / 12 PHE A 643
PHE A 441
GLY A 431
ALA A 429
ILE A 321
 None
 1.48A 3ld6B-5ys9A:
undetectable		 3ld6B-5ys9A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		3 / 3 ASN A 491
ALA A 490
LYS A 492
 None
 0.78A 3runA-5ys9A:
undetectable		 3runA-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 5 LEU A 233
ALA A 212
PHE A 129
ASN A 275
 None
 1.27A 3uq6A-5ys9A:
undetectable		 3uq6A-5ys9A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 4 LEU A 233
ALA A 212
PHE A 129
ASN A 275
 None
 1.33A 3vaqA-5ys9A:
undetectable		 3vaqA-5ys9A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 4 LEU A 233
ALA A 212
PHE A 129
ASN A 275
 None
 1.30A 3vasA-5ys9A:
undetectable		 3vasA-5ys9A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 8 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.04A 3wg7A-5ys9A:
2.6
3wg7C-5ys9A:
3.3
3wg7P-5ys9A:
3.3		 3wg7A-5ys9A:
undetectable
3wg7C-5ys9A:
undetectable
3wg7P-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 8 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.05A 3x2qA-5ys9A:
3.1
3x2qC-5ys9A:
3.3
3x2qP-5ys9A:
3.3		 3x2qA-5ys9A:
undetectable
3x2qC-5ys9A:
undetectable
3x2qP-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 8 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.06A 3x2qC-5ys9A:
3.3
3x2qN-5ys9A:
2.6
3x2qP-5ys9A:
3.3		 3x2qC-5ys9A:
undetectable
3x2qN-5ys9A:
undetectable
3x2qP-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		5 / 11 ASN A 261
GLY A 248
ALA A 196
GLU A 175
ASN A 193
 FAD  A 801 (-3.7A)
None
None
None
None
 1.18A 4a6nA-5ys9A:
undetectable		 4a6nA-5ys9A:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		5 / 12 GLY A 203
ALA A 208
ILE A 259
VAL A 124
ILE A 120
 None
 1.11A 4aztA-5ys9A:
undetectable		 4aztA-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 TYR A  74
PRO A 647
PHE A 320
ARG A 319
 None
 1.50A 4kf9A-5ys9A:
undetectable		 4kf9A-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		5 / 12 ASN A 459
VAL A 460
GLY A 466
ILE A 470
ILE A 522
 FAD  A 801 (-4.9A)
FAD  A 801 (-4.8A)
None
None
None
 1.25A 4xucA-5ys9A:
undetectable		 4xucA-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 7 LEU A 105
SER A 108
GLY A 123
ILE A 120
 None
 0.74A 4yjiA-5ys9A:
undetectable		 4yjiA-5ys9A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		5 / 12 ILE A 264
PHE A 160
VAL A 124
ILE A 189
VAL A 231
 None
FAD  A 801 (-4.9A)
None
None
None
 1.16A 5n0sB-5ys9A:
undetectable		 5n0sB-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		3 / 3 LYS A 560
HIS A 557
HIS A 561
 None
 0.84A 5oexA-5ys9A:
undetectable		 5oexA-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		3 / 3 LYS A 560
HIS A 557
HIS A 561
 None
 0.81A 5oexB-5ys9A:
undetectable		 5oexB-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		3 / 3 LYS A 560
HIS A 557
HIS A 561
 None
 0.77A 5oexC-5ys9A:
undetectable		 5oexC-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		3 / 3 LYS A 560
HIS A 557
HIS A 561
 None
 0.82A 5oexD-5ys9A:
undetectable		 5oexD-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 7 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.06A 6nmfA-5ys9A:
undetectable
6nmfC-5ys9A:
2.4
6nmfP-5ys9A:
3.2		 6nmfA-5ys9A:
undetectable
6nmfC-5ys9A:
undetectable
6nmfP-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 7 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.06A 6nmfN-5ys9A:
0.1
6nmfP-5ys9A:
3.1		 6nmfN-5ys9A:
undetectable
6nmfP-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 6 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.02A 6nmpA-5ys9A:
undetectable
6nmpC-5ys9A:
3.1		 6nmpA-5ys9A:
undetectable
6nmpC-5ys9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ys9 ACYL-COENZYME A
OXIDASE 3
(Yarrowia
lipolytica) 		4 / 7 ASP A 635
THR A 634
TYR A 633
HIS A 351
 None
 1.06A 6nmpN-5ys9A:
2.8
6nmpP-5ys9A:
3.2		 6nmpN-5ys9A:
undetectable
6nmpP-5ys9A:
undetectable