SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yt7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5yt7	- (-)	4 / 4	HIS A 65 CYH A 131 HIS A 3 MET A 7	CU A 201 (-3.1A) CU A 201 (-2.1A) CU A 201 (-3.1A) CU A 201 (-3.2A)	0.39A	1oe1A-5yt7A: undetectable	1oe1A-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5yt7	- (-)	4 / 5	HIS A 65 CYH A 131 HIS A 3 MET A 7	CU A 201 (-3.1A) CU A 201 (-2.1A) CU A 201 (-3.1A) CU A 201 (-3.2A)	0.39A	1oe2A-5yt7A: 5.7	1oe2A-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5yt7	- (-)	4 / 4	HIS A 65 CYH A 131 HIS A 3 MET A 7	CU A 201 (-3.1A) CU A 201 (-2.1A) CU A 201 (-3.1A) CU A 201 (-3.2A)	0.43A	1oe3A-5yt7A: undetectable	1oe3A-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQD_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	5yt7	- (-)	4 / 4	HIS A 65 CYH A 131 HIS A 3 MET A 7	CU A 201 (-3.1A) CU A 201 (-2.1A) CU A 201 (-3.1A) CU A 201 (-3.2A)	0.49A	2fqdA-5yt7A: undetectable	2fqdA-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQE_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	5yt7	- (-)	4 / 4	HIS A 65 CYH A 131 HIS A 3 MET A 7	CU A 201 (-3.1A) CU A 201 (-2.1A) CU A 201 (-3.1A) CU A 201 (-3.2A)	0.47A	2fqeA-5yt7A: undetectable	2fqeA-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQF_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	5yt7	- (-)	4 / 4	HIS A 65 CYH A 131 HIS A 3 MET A 7	CU A 201 (-3.1A) CU A 201 (-2.1A) CU A 201 (-3.1A) CU A 201 (-3.2A)	0.47A	2fqfA-5yt7A: undetectable	2fqfA-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQG_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	5yt7	- (-)	4 / 4	HIS A 65 CYH A 131 HIS A 3 MET A 7	CU A 201 (-3.1A) CU A 201 (-2.1A) CU A 201 (-3.1A) CU A 201 (-3.2A)	0.50A	2fqgA-5yt7A: undetectable	2fqgA-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QBN_A_CAMA442_0 (CYTOCHROME P450-CAM)	5yt7	- (-)	4 / 7	VAL A 68 VAL A 114 ASP A 112 VAL A 50	None None CA A 202 ( 2.7A) None	0.98A	2qbnA-5yt7A: undetectable	2qbnA-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1337_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5yt7	- (-)	4 / 4	HIS A 65 CYH A 131 HIS A 3 MET A 7	CU A 201 (-3.1A) CU A 201 (-2.1A) CU A 201 (-3.1A) CU A 201 (-3.2A)	0.40A	2xxgA-5yt7A: 4.3	2xxgA-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5yt7	- (-)	4 / 5	HIS A 65 CYH A 131 HIS A 3 MET A 7	CU A 201 (-3.1A) CU A 201 (-2.1A) CU A 201 (-3.1A) CU A 201 (-3.2A)	0.42A	2xxgC-5yt7A: 4.2	2xxgC-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IK3_A_0LIA1_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	5yt7	- (-)	4 / 7	LEU A 87 TYR A 91 VAL A 50 MET A 63	None	0.91A	3ik3A-5yt7A: undetectable	3ik3A-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MIH_A_CUA358_0 (PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE)	5yt7	- (-)	3 / 3	HIS A 3 HIS A 65 MET A 63	CU A 201 (-3.1A) CU A 201 (-3.1A) None	1.02A	3mihA-5yt7A: undetectable	3mihA-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EF3_A_CUA1001_0 (BLUE COPPER OXIDASE CUEO)	5yt7	- (-)	4 / 4	HIS A 65 CYH A 131 HIS A 3 MET A 7	CU A 201 (-3.1A) CU A 201 (-2.1A) CU A 201 (-3.1A) CU A 201 (-3.2A)	0.48A	4ef3A-5yt7A: undetectable	4ef3A-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RZV_A_032A801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5yt7	- (-)	5 / 12	ILE A 106 THR A 103 SER A 23 PHE A 34 GLY A 28	None None NA A 205 (-4.2A) None None	0.81A	4rzvA-5yt7A: undetectable	4rzvA-5yt7A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F32_B_ACTB602_0 (AMINE OXIDASE LKCE)	5yt7	- (-)	4 / 6	ASN A 66 TYR A 91 VAL A 68 VAL A 79	None	1.42A	6f32B-5yt7A: undetectable	6f32B-5yt7A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE1_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5yt7","-","-",4,"HIS A  65;CYH A 131;HIS A   3;MET A   7"," CU A 201 (-3.1A); CU A 201 (-2.1A); CU A 201 (-3.1A); CU A 201 (-3.2A)","0.39A","1oe1A-5yt7A:undetectable","1oe1A-5yt7A:undetectable"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5yt7","-","-",4,"HIS A  65;CYH A 131;HIS A   3;MET A   7"," CU A 201 (-3.1A); CU A 201 (-2.1A); CU A 201 (-3.1A); CU A 201 (-3.2A)","0.39A","1oe2A-5yt7A:5.7","1oe2A-5yt7A:undetectable"],["1OE3_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5yt7","-","-",4,"HIS A  65;CYH A 131;HIS A   3;MET A   7"," CU A 201 (-3.1A); CU A 201 (-2.1A); CU A 201 (-3.1A); CU A 201 (-3.2A)","0.43A","1oe3A-5yt7A:undetectable","1oe3A-5yt7A:undetectable"],["2FQD_A_CUA601_0","BLUE COPPER OXIDASE CUEO","5yt7","-","-",4,"HIS A  65;CYH A 131;HIS A   3;MET A   7"," CU A 201 (-3.1A); CU A 201 (-2.1A); CU A 201 (-3.1A); CU A 201 (-3.2A)","0.49A","2fqdA-5yt7A:undetectable","2fqdA-5yt7A:undetectable"],["2FQE_A_CUA601_0","BLUE COPPER OXIDASE CUEO","5yt7","-","-",4,"HIS A  65;CYH A 131;HIS A   3;MET A   7"," CU A 201 (-3.1A); CU A 201 (-2.1A); CU A 201 (-3.1A); CU A 201 (-3.2A)","0.47A","2fqeA-5yt7A:undetectable","2fqeA-5yt7A:undetectable"],["2FQF_A_CUA601_0","BLUE COPPER OXIDASE CUEO","5yt7","-","-",4,"HIS A  65;CYH A 131;HIS A   3;MET A   7"," CU A 201 (-3.1A); CU A 201 (-2.1A); CU A 201 (-3.1A); CU A 201 (-3.2A)","0.47A","2fqfA-5yt7A:undetectable","2fqfA-5yt7A:undetectable"],["2FQG_A_CUA601_0","BLUE COPPER OXIDASE CUEO","5yt7","-","-",4,"HIS A  65;CYH A 131;HIS A   3;MET A   7"," CU A 201 (-3.1A); CU A 201 (-2.1A); CU A 201 (-3.1A); CU A 201 (-3.2A)","0.50A","2fqgA-5yt7A:undetectable","2fqgA-5yt7A:undetectable"],["2QBN_A_CAMA442_0","CYTOCHROME P450-CAM","5yt7","-","-",4,"VAL A  68;VAL A 114;ASP A 112;VAL A  50","None;None; CA A 202 ( 2.7A);None","0.98A","2qbnA-5yt7A:undetectable","2qbnA-5yt7A:undetectable"],["2XXG_A_CUA1337_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5yt7","-","-",4,"HIS A  65;CYH A 131;HIS A   3;MET A   7"," CU A 201 (-3.1A); CU A 201 (-2.1A); CU A 201 (-3.1A); CU A 201 (-3.2A)","0.40A","2xxgA-5yt7A:4.3","2xxgA-5yt7A:undetectable"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5yt7","-","-",4,"HIS A  65;CYH A 131;HIS A   3;MET A   7"," CU A 201 (-3.1A); CU A 201 (-2.1A); CU A 201 (-3.1A); CU A 201 (-3.2A)","0.42A","2xxgC-5yt7A:4.2","2xxgC-5yt7A:undetectable"],["3IK3_A_0LIA1_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","5yt7","-","-",4,"LEU A  87;TYR A  91;VAL A  50;MET A  63","None","0.91A","3ik3A-5yt7A:undetectable","3ik3A-5yt7A:undetectable"],["3MIH_A_CUA358_0","PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE","5yt7","-","-",3,"HIS A   3;HIS A  65;MET A  63"," CU A 201 (-3.1A); CU A 201 (-3.1A);None","1.02A","3mihA-5yt7A:undetectable","3mihA-5yt7A:undetectable"],["4EF3_A_CUA1001_0","BLUE COPPER OXIDASE CUEO","5yt7","-","-",4,"HIS A  65;CYH A 131;HIS A   3;MET A   7"," CU A 201 (-3.1A); CU A 201 (-2.1A); CU A 201 (-3.1A); CU A 201 (-3.2A)","0.48A","4ef3A-5yt7A:undetectable","4ef3A-5yt7A:undetectable"],["4RZV_A_032A801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5yt7","-","-",5,"ILE A 106;THR A 103;SER A  23;PHE A  34;GLY A  28","None;None; NA A 205 (-4.2A);None;None","0.81A","4rzvA-5yt7A:undetectable","4rzvA-5yt7A:undetectable"],["6F32_B_ACTB602_0","AMINE OXIDASE LKCE","5yt7","-","-",4,"ASN A  66;TYR A  91;VAL A  68;VAL A  79","None","1.42A","6f32B-5yt7A:undetectable","6f32B-5yt7A:undetectable"]]