SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 5yua ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		4 / 7 VAL A1052
THR A1054
PHE A1056
THR A1057
 None
 1.24A 2kotA-5yuaA:
undetectable		 2kotA-5yuaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5yua ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		4 / 6 PHE A1201
PRO A1200
THR A1206
ILE A1202
 None
None
LMT  A1302 (-4.2A)
None
 1.29A 5ih0A-5yuaA:
undetectable		 5ih0A-5yuaA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 5yua ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		4 / 6 THR A1162
GLY A1164
GLU A1165
PHE A1167
 None
 0.13A 5kmfA-5yuaA:
23.6
5kmfC-5yuaA:
24.0		 5kmfA-5yuaA:
94.12
5kmfC-5yuaA:
94.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 5yua ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		4 / 6 MET A1174
THR A1175
LEU A1176
MET A1209
 LMT  A1302 (-3.1A)
LMT  A1302 (-4.9A)
LMT  A1302 (-4.4A)
LMT  A1302 (-4.3A)
 0.41A 6mvxA-5yuaA:
21.9
6mvxB-5yuaA:
19.6
6mvxC-5yuaA:
18.2		 6mvxA-5yuaA:
undetectable
6mvxB-5yuaA:
undetectable
6mvxC-5yuaA:
undetectable