SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ywo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5ywo 2F2 HEAVY CHAIN
(Mus
musculus) 		5 / 11 VAL N 116
GLU N  10
LEU N  81
ILE N  83
ASP N  90
 None
 1.44A 1t6zB-5ywoN:
undetectable		 1t6zB-5ywoN:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 5ywo 2F2 HEAVY CHAIN
(Mus
musculus) 		3 / 3 TYR N 180
GLY N 149
PHE N 151
 None
 0.68A 2m2pB-5ywoN:
undetectable		 2m2pB-5ywoN:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 5ywo 2F2 HEAVY CHAIN
(Mus
musculus) 		3 / 3 MET N  34
VAL N 107
GLU N   6
 None
 0.91A 3c6gA-5ywoN:
undetectable		 3c6gA-5ywoN:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 5ywo 2F2 HEAVY CHAIN
(Mus
musculus) 		4 / 7 TYR N  27
ARG N 101
HIS N  35
ALA N  97
 None
 1.39A 3frqB-5ywoN:
undetectable		 3frqB-5ywoN:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ywo 2F2 HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR N 115
GLU N 153
HIS N 204
 None
 0.82A 3g1uB-5ywoN:
undetectable		 3g1uB-5ywoN:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5ywo 2F2 HEAVY CHAIN
(Mus
musculus) 		4 / 6 VAL N 116
ARG N  67
VAL N  18
PHE N  68
 None
 1.37A 3jx4A-5ywoN:
undetectable
3jx4B-5ywoN:
undetectable		 3jx4A-5ywoN:
11.27
3jx4B-5ywoN:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1480_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5ywo 2F2 HEAVY CHAIN
(Mus
musculus) 		4 / 4 LYS N  13
GLU N  89
ILE N  88
SER N 117
 None
 1.18A 4acaC-5ywoN:
undetectable		 4acaC-5ywoN:
undetectable