SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ywp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 9 LEU A 180
PHE A 167
LEU A 188
GLY A 140
LEU A  41
 None
 1.26A 1e7aB-5ywpA:
undetectable		 1e7aB-5ywpA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 6 THR A 226
PHE A 218
GLU A  55
GLY A 127
 None
 1.16A 1icuA-5ywpA:
undetectable
1icuB-5ywpA:
undetectable		 1icuA-5ywpA:
18.81
1icuB-5ywpA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 6 PHE A 218
GLU A  55
GLY A 127
THR A 226
 None
 1.12A 1icuA-5ywpA:
undetectable
1icuB-5ywpA:
undetectable		 1icuA-5ywpA:
18.81
1icuB-5ywpA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 6 THR A 226
PHE A 218
GLU A  55
GLY A 127
 None
 1.13A 1icuC-5ywpA:
undetectable
1icuD-5ywpA:
undetectable		 1icuC-5ywpA:
18.81
1icuD-5ywpA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5ywp JEV E PROTEIN
JEV M PROTEIN
(Japanese
encephalitis
virus;
Japanese
encephalitis
virus) 		4 / 8 SER A 275
ILE A  48
VAL A 203
SER B  10
 None
 1.10A 1kb9A-5ywpA:
undetectable
1kb9C-5ywpA:
undetectable
1kb9D-5ywpA:
undetectable
1kb9E-5ywpA:
1.4		 1kb9A-5ywpA:
undetectable
1kb9C-5ywpA:
undetectable
1kb9D-5ywpA:
undetectable
1kb9E-5ywpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 7 VAL A 186
VAL A  43
LEU A  31
LEU A 188
 None
 0.75A 1pthA-5ywpA:
undetectable		 1pthA-5ywpA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 7 VAL A 186
VAL A  43
LEU A  31
LEU A 188
 None
 0.75A 1pthB-5ywpA:
undetectable		 1pthB-5ywpA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 7 TRP A 225
PRO A 227
ARG A  57
GLY A 127
 None
 0.97A 2hs1B-5ywpA:
undetectable		 2hs1B-5ywpA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 6 TRP A 225
PRO A 227
ARG A  57
GLY A 127
 None
 0.97A 2hs2B-5ywpA:
undetectable		 2hs2B-5ywpA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 10 LEU A 180
ALA A 165
LEU A 188
VAL A 186
ILE A  33
 None
 1.09A 2w9gA-5ywpA:
undetectable		 2w9gA-5ywpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 10 LEU A 180
ALA A 165
LEU A 188
VAL A 186
ILE A  33
 None
 1.07A 2w9hA-5ywpA:
undetectable		 2w9hA-5ywpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 11 LEU A 180
ALA A 165
LEU A 188
VAL A 186
ILE A  33
 None
 1.10A 3frbX-5ywpA:
undetectable		 3frbX-5ywpA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_A_478A200_1
(HIV-1 PROTEASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 6 TRP A 225
PRO A 227
ARG A  57
GLY A 127
 None
 1.12A 3oxvA-5ywpA:
undetectable		 3oxvA-5ywpA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_B_017B203_1
(PROTEASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 5 TRP A 225
PRO A 227
ARG A  57
GLY A 127
 None
 1.08A 3s53B-5ywpA:
undetectable		 3s53B-5ywpA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 7 TRP A 225
PRO A 227
ARG A  57
GLY A 127
 None
 1.00A 3ucbB-5ywpA:
undetectable		 3ucbB-5ywpA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 6 ILE A  33
THR A  40
VAL A  24
ASP A  28
 None
 1.12A 4iaqA-5ywpA:
undetectable		 4iaqA-5ywpA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 7 ILE A  33
THR A  40
VAL A  24
ASP A  28
 None
 1.16A 4iarA-5ywpA:
undetectable		 4iarA-5ywpA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 8 LEU A  41
THR A  32
ARG A   9
VAL A 355
 None
 0.82A 4qknA-5ywpA:
undetectable		 4qknA-5ywpA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 5 ARG A 353
GLY A 352
THR A 321
GLU A 375
 None
 1.06A 5btiA-5ywpA:
undetectable
5btiB-5ywpA:
undetectable		 5btiA-5ywpA:
11.24
5btiB-5ywpA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 5 ARG A 353
GLY A 352
THR A 321
GLU A 375
 None
 1.07A 5btiC-5ywpA:
undetectable
5btiD-5ywpA:
undetectable		 5btiC-5ywpA:
11.24
5btiD-5ywpA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ASP A 332
SER A 329
TYR A 328
 None
 0.91A 5glmA-5ywpA:
undetectable		 5glmA-5ywpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 6 LYS A  84
SER A 251
VAL A 252
ASP A  67
 None
 1.24A 5hesA-5ywpA:
undetectable		 5hesA-5ywpA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 7 LEU A 289
THR A  40
THR A 356
LEU A  23
 None
 1.11A 5jq7B-5ywpA:
undetectable		 5jq7B-5ywpA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		3 / 3 THR A 317
GLU A 373
HIS A 144
 None
 0.67A 5xioA-5ywpA:
undetectable		 5xioA-5ywpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		3 / 3 THR A 317
GLU A 373
HIS A 144
 None
 0.68A 5xiqB-5ywpA:
undetectable		 5xiqB-5ywpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		3 / 3 THR A 317
GLU A 373
HIS A 144
 None
 0.62A 5xiqD-5ywpA:
undetectable		 5xiqD-5ywpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 5 LEU A 280
THR A 129
PRO A 171
ARG A 193
 None
 1.24A 6ew0B-5ywpA:
undetectable		 6ew0B-5ywpA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 5 LEU A 280
THR A 129
PRO A 171
ARG A 193
 None
 1.23A 6ew0D-5ywpA:
undetectable		 6ew0D-5ywpA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 5 LEU A 280
THR A 129
PRO A 171
ARG A 193
 None
 1.23A 6ew0H-5ywpA:
undetectable		 6ew0H-5ywpA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		4 / 5 LEU A 280
THR A 129
PRO A 171
ARG A 193
 None
 1.22A 6ew0I-5ywpA:
undetectable		 6ew0I-5ywpA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 12 THR A 317
THR A 321
ASP A  42
GLY A   5
PHE A  11
 None
 1.29A 6exiA-5ywpA:
undetectable		 6exiA-5ywpA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLY A 111
GLY A 109
THR A  97
ILE A 113
GLN A 250
 None
 1.13A 6exiC-5ywpA:
undetectable
6exiD-5ywpA:
undetectable		 6exiC-5ywpA:
25.00
6exiD-5ywpA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLN A 158
ASP A  42
LEU A 371
HIS A 144
PHE A   1
 None
 1.22A 6exiD-5ywpA:
undetectable		 6exiD-5ywpA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 12 GLN A 250
GLY A 111
GLY A 109
THR A  97
ILE A 113
 None
 1.01A 6exiC-5ywpA:
undetectable
6exiD-5ywpA:
undetectable		 6exiC-5ywpA:
25.00
6exiD-5ywpA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.47A 6f3mA-5ywpA:
undetectable		 6f3mA-5ywpA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.48A 6f3mC-5ywpA:
undetectable		 6f3mC-5ywpA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 5ywp JEV E PROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.47A 6f3nC-5ywpA:
undetectable		 6f3nC-5ywpA:
10.38