SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ywz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 GLU A 823
THR A 821
HIS A 908
LEU A 747
 None
 1.40A 1d4fC-5ywzA:
undetectable		 1d4fC-5ywzA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 4 THR A 828
LEU A 829
LEU A 777
GLN A 677
 None
 1.25A 1fbmA-5ywzA:
undetectable		 1fbmA-5ywzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 12 LEU A 683
ALA A 724
ILE A 727
ILE A 707
ALA A 710
 None
 1.06A 2bxcA-5ywzA:
2.2		 2bxcA-5ywzA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 LEU A 811
ARG A 810
ALA A 746
ILE A 885
 None
 0.98A 2qhfA-5ywzA:
undetectable		 2qhfA-5ywzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 GLN A 789
GLU A 823
THR A 821
HIS A 908
 None
 1.15A 3glqA-5ywzA:
undetectable		 3glqA-5ywzA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 GLN A 789
GLU A 823
THR A 821
HIS A 908
 None
 1.28A 3glqB-5ywzA:
undetectable		 3glqB-5ywzA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 11 ILE A 719
VAL A 708
ILE A 707
ASN A 730
ILE A 727
 None
 1.14A 3kpcA-5ywzA:
undetectable		 3kpcA-5ywzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 12 ILE A 719
VAL A 708
ILE A 707
ASN A 730
ILE A 727
 None
 1.10A 3kpdB-5ywzA:
undetectable		 3kpdB-5ywzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 11 GLN A 789
PRO A 790
ASP A 791
THR A 692
ILE A 691
 None
 0.93A 3n23A-5ywzA:
undetectable		 3n23A-5ywzA:
5.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 GLN A 789
GLU A 823
THR A 821
HIS A 908
 None
 1.33A 3n58A-5ywzA:
undetectable		 3n58A-5ywzA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 7 THR A 818
GLY A 909
THR A 819
VAL A 743
 None
 0.82A 4qwpB-5ywzA:
undetectable		 4qwpB-5ywzA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 TYR A 903
TYR A 779
GLU A 684
LEU A 769
 None
 1.44A 4qztB-5ywzA:
undetectable		 4qztB-5ywzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		5 / 12 THR A 767
LEU A 769
ILE A 727
VAL A 786
ARG A 904
 None
 1.19A 5dlvB-5ywzA:
undetectable		 5dlvB-5ywzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 THR A 696
THR A 692
TYR A 735
HIS A 693
 None
 1.04A 5ecmA-5ywzA:
undetectable		 5ecmA-5ywzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 5 ALA A 768
TYR A 779
GLY A 718
LEU A 687
 None
 0.78A 5eslA-5ywzA:
undetectable		 5eslA-5ywzA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1
(Mus
musculus) 		4 / 6 PRO A 826
ILE A 792
TYR A 903
GLU A 823
 None
 0.69A 6gqiA-5ywzA:
2.5		 6gqiA-5ywzA:
undetectable