SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yx3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK1_A_T44A3004_1 (SERUM ALBUMIN)	5yx3	CHALCONE-FLAVONONE ISOMERASE FAMILY PROTEIN (Deschampsia antarctica)	4 / 6	PHE A 79 GLU A 187 LEU A 186 VAL A 49	None	1.02A	1hk1A-5yx3A: undetectable	1hk1A-5yx3A: 7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK3_A_T44A3004_1 (SERUM ALBUMIN)	5yx3	CHALCONE-FLAVONONE ISOMERASE FAMILY PROTEIN (Deschampsia antarctica)	4 / 7	PHE A 79 GLU A 187 LEU A 186 VAL A 49	None	0.99A	1hk3A-5yx3A: undetectable	1hk3A-5yx3A: 8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y7I_B_SALB503_1 (SALICYLIC ACID-BINDING PROTEIN 2)	5yx3	CHALCONE-FLAVONONE ISOMERASE FAMILY PROTEIN (Deschampsia antarctica)	5 / 10	ALA A 56 LEU A 60 PHE A 78 PHE A 26 LEU A 211	None	1.43A	1y7iB-5yx3A: undetectable	1y7iB-5yx3A: 15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJG_B_NCTB501_1 (CYTOCHROME P450 2A13)	5yx3	CHALCONE-FLAVONONE ISOMERASE FAMILY PROTEIN (Deschampsia antarctica)	4 / 8	PHE A 26 PHE A 87 LEU A 211 LEU A 210	None	0.87A	4ejgB-5yx3A: undetectable	4ejgB-5yx3A: 11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKQ_A_JMSA602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	5yx3	CHALCONE-FLAVONONE ISOMERASE FAMILY PROTEIN (Deschampsia antarctica)	3 / 3	VAL A 7 SER A 196 MET A 35	None	0.74A	5ikqA-5yx3A: undetectable	5ikqA-5yx3A: 9.94

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HK1_A_T44A3004_1","SERUM ALBUMIN","5yx3","CHALCONE-FLAVONONE ISOMERASE FAMILY PROTEIN","Deschampsia antarctica",4,"PHE A  79;GLU A 187;LEU A 186;VAL A  49","None","1.02A","1hk1A-5yx3A:undetectable","1hk1A-5yx3A:7.88"],["1HK3_A_T44A3004_1","SERUM ALBUMIN","5yx3","CHALCONE-FLAVONONE ISOMERASE FAMILY PROTEIN","Deschampsia antarctica",4,"PHE A  79;GLU A 187;LEU A 186;VAL A  49","None","0.99A","1hk3A-5yx3A:undetectable","1hk3A-5yx3A:8.22"],["1Y7I_B_SALB503_1","SALICYLIC ACID-BINDING PROTEIN 2","5yx3","CHALCONE-FLAVONONE ISOMERASE FAMILY PROTEIN","Deschampsia antarctica",5,"ALA A  56;LEU A  60;PHE A  78;PHE A  26;LEU A 211","None","1.43A","1y7iB-5yx3A:undetectable","1y7iB-5yx3A:15.06"],["4EJG_B_NCTB501_1","CYTOCHROME P450 2A13","5yx3","CHALCONE-FLAVONONE ISOMERASE FAMILY PROTEIN","Deschampsia antarctica",4,"PHE A  26;PHE A  87;LEU A 211;LEU A 210","None","0.87A","4ejgB-5yx3A:undetectable","4ejgB-5yx3A:11.37"],["5IKQ_A_JMSA602_2","PROSTAGLANDIN G\/H SYNTHASE 2","5yx3","CHALCONE-FLAVONONE ISOMERASE FAMILY PROTEIN","Deschampsia antarctica",3,"VAL A   7;SER A 196;MET A  35","None","0.74A","5ikqA-5yx3A:undetectable","5ikqA-5yx3A:9.94"]]