SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yz2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OI8_A_ADNA2_1 (UNCHARACTERIZED PROTEIN)	5yz2	MAGNESIUM AND COBALT EFFLUX PROTEIN CORC (Escherichia coli)	5 / 6	ILE A 74 HIS A 100 PRO A 104 LEU A 178 ASP A 183	AMP A 301 ( 4.2A) AMP A 301 (-3.4A) AMP A 301 ( 4.6A) None AMP A 301 (-1.9A)	0.43A	3oi8A-5yz2A: 20.8	3oi8A-5yz2A: 31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OI8_B_ADNB1_1 (UNCHARACTERIZED PROTEIN)	5yz2	MAGNESIUM AND COBALT EFFLUX PROTEIN CORC (Escherichia coli)	7 / 9	ILE A 74 HIS A 100 PRO A 104 LEU A 178 THR A 180 GLU A 182 ASP A 183	AMP A 301 ( 4.2A) AMP A 301 (-3.4A) AMP A 301 ( 4.6A) None AMP A 301 (-2.4A) None AMP A 301 (-1.9A)	0.93A	3oi8A-5yz2A: 20.8 3oi8B-5yz2A: 20.7	3oi8A-5yz2A: 31.82 3oi8B-5yz2A: 31.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MKE_C_FK5C201_0 (PEPTIDYLPROLYL ISOMERASE)	5yz2	MAGNESIUM AND COBALT EFFLUX PROTEIN CORC (Escherichia coli)	4 / 4	ASP A 121 ILE A 116 PRO A 104 LEU A 117	None None AMP A 301 ( 4.6A) None	1.18A	6mkeB-5yz2A: undetectable	6mkeB-5yz2A: 25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MKE_D_FK5D201_0 (PEPTIDYLPROLYL ISOMERASE)	5yz2	MAGNESIUM AND COBALT EFFLUX PROTEIN CORC (Escherichia coli)	4 / 4	ASP A 121 ILE A 116 PRO A 104 LEU A 117	None None AMP A 301 ( 4.6A) None	1.08A	6mkeA-5yz2A: undetectable	6mkeA-5yz2A: 25.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3OI8_A_ADNA2_1","UNCHARACTERIZED PROTEIN","5yz2","MAGNESIUM AND COBALT EFFLUX PROTEIN CORC","Escherichia coli",5,"ILE A  74;HIS A 100;PRO A 104;LEU A 178;ASP A 183","AMP A 301 ( 4.2A);AMP A 301 (-3.4A);AMP A 301 ( 4.6A);None;AMP A 301 (-1.9A)","0.43A","3oi8A-5yz2A:20.8","3oi8A-5yz2A:31.82"],["3OI8_B_ADNB1_1","UNCHARACTERIZED PROTEIN;UNCHARACTERIZED PROTEIN","5yz2","MAGNESIUM AND COBALT EFFLUX PROTEIN CORC","Escherichia coli",7,"ILE A  74;HIS A 100;PRO A 104;LEU A 178;THR A 180;GLU A 182;ASP A 183","AMP A 301 ( 4.2A);AMP A 301 (-3.4A);AMP A 301 ( 4.6A);None;AMP A 301 (-2.4A);None;AMP A 301 (-1.9A)","0.93A","3oi8A-5yz2A:20.8;3oi8B-5yz2A:20.7","3oi8A-5yz2A:31.82;3oi8B-5yz2A:31.82"],["6MKE_C_FK5C201_0","PEPTIDYLPROLYL ISOMERASE","5yz2","MAGNESIUM AND COBALT EFFLUX PROTEIN CORC","Escherichia coli",4,"ASP A 121;ILE A 116;PRO A 104;LEU A 117","None;None;AMP A 301 ( 4.6A);None","1.18A","6mkeB-5yz2A:undetectable","6mkeB-5yz2A:25.29"],["6MKE_D_FK5D201_0","PEPTIDYLPROLYL ISOMERASE","5yz2","MAGNESIUM AND COBALT EFFLUX PROTEIN CORC","Escherichia coli",4,"ASP A 121;ILE A 116;PRO A 104;LEU A 117","None;None;AMP A 301 ( 4.6A);None","1.08A","6mkeA-5yz2A:undetectable","6mkeA-5yz2A:25.29"]]