SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yzc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
GLYCOPROTEIN F2
(Measles
morbillivirus) 		5 / 12 GLY A  34
ILE A  25
GLY A  37
ILE A  38
VAL B 315
 None
 1.03A 2b7zA-5yzcA:
undetectable		 2b7zA-5yzcA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
GLYCOPROTEIN F2
(Measles
morbillivirus) 		5 / 10 LEU B 216
PHE B 217
LEU B 238
ILE A  56
ALA B 267
 None
 1.10A 2bxeB-5yzcB:
undetectable		 2bxeB-5yzcB:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
GLYCOPROTEIN F2
(Measles
morbillivirus) 		4 / 6 ILE A  62
TYR B 181
MET B 190
ILE B 187
 None
 1.21A 3eteA-5yzcA:
undetectable
3eteE-5yzcA:
undetectable		 3eteA-5yzcA:
9.96
3eteE-5yzcA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
GLYCOPROTEIN F2
(Measles
morbillivirus) 		4 / 5 ILE A  62
TYR B 181
MET B 190
ILE B 187
 None
 1.18A 3eteB-5yzcA:
undetectable
3eteC-5yzcA:
undetectable		 3eteB-5yzcA:
9.96
3eteC-5yzcA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
(Measles
morbillivirus) 		5 / 10 LEU B 246
ILE B 265
PRO B 286
SER B 344
GLY B 264
 None
 1.31A 3ijxB-5yzcB:
undetectable
3ijxD-5yzcB:
undetectable		 3ijxB-5yzcB:
14.40
3ijxD-5yzcB:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
(Measles
morbillivirus) 		5 / 10 LEU B 246
ILE B 265
PRO B 286
SER B 344
GLY B 264
 None
 1.30A 3ik6B-5yzcB:
undetectable
3ik6E-5yzcB:
undetectable		 3ik6B-5yzcB:
14.40
3ik6E-5yzcB:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
(Measles
morbillivirus) 		5 / 10 LEU B 246
ILE B 265
PRO B 286
SER B 344
GLY B 264
 None
 1.31A 3iluB-5yzcB:
undetectable
3iluE-5yzcB:
undetectable		 3iluB-5yzcB:
14.40
3iluE-5yzcB:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
(Measles
morbillivirus) 		5 / 11 ILE B 265
PRO B 286
SER B 344
GLY B 264
LEU B 246
 None
 1.32A 3iluB-5yzcB:
undetectable
3iluE-5yzcB:
undetectable		 3iluB-5yzcB:
14.40
3iluE-5yzcB:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
GLYCOPROTEIN F2
(Measles
morbillivirus) 		5 / 12 LEU A  84
GLY B 218
ILE B 229
VAL B 272
ILE A  87
 None
 0.98A 3pwmB-5yzcA:
undetectable		 3pwmB-5yzcA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
(Measles
morbillivirus) 		4 / 5 LEU B 123
GLY B 124
ILE B 131
GLN B 130
 None
 0.99A 4ma8C-5yzcB:
undetectable		 4ma8C-5yzcB:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
GLYCOPROTEIN F2
(Measles
morbillivirus) 		5 / 9 VAL B 280
LEU B 281
SER A  53
LEU B 142
ALA B 174
 None
 1.11A 4rs0A-5yzcB:
undetectable		 4rs0A-5yzcB:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
(Measles
morbillivirus) 		5 / 9 TYR B 251
ALA B 284
ILE B 283
GLY B 250
SER B 262
 None
 1.36A 6awoA-5yzcB:
undetectable		 6awoA-5yzcB:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
(Measles
morbillivirus) 		5 / 9 TYR B 251
ALA B 284
ILE B 283
GLY B 250
SER B 262
 None
 1.37A 6awqA-5yzcB:
undetectable		 6awqA-5yzcB:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 5yzc GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
(Measles
morbillivirus) 		3 / 3 SER B 365
LYS B 364
SER B 362
 None
 0.77A 6az3P-5yzcB:
undetectable		 6az3P-5yzcB:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 5yzc GLYCOPROTEIN F2
GLYCOPROTEIN
F1,MEASLES VIRUS
FUSION PROTEIN
(Measles
morbillivirus;
Measles
morbillivirus) 		5 / 12 LEU A  84
GLY B 218
ILE B 229
VAL B 272
ILE A  87
 None
 0.95A 6dgxA-5yzcA:
undetectable		 6dgxA-5yzcA:
15.00