SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5yzz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 5yzz B3 DOMAIN-CONTAINING
TRANSCRIPTION
REPRESSOR VAL1
(Arabidopsis
thaliana) 		5 / 12 PHE C 295
LEU C 332
PHE C 344
ILE C 366
GLY C 391
 None
 1.06A 3nxuA-5yzzC:
undetectable		 3nxuA-5yzzC:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 5yzz B3 DOMAIN-CONTAINING
TRANSCRIPTION
REPRESSOR VAL1
(Arabidopsis
thaliana) 		5 / 10 PRO C 313
ALA C 319
GLU C 296
PHE C 321
LEU C 359
 None
 1.09A 4la0A-5yzzC:
undetectable		 4la0A-5yzzC:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_B_198B601_1
(SERUM ALBUMIN)		 5yzz B3 DOMAIN-CONTAINING
TRANSCRIPTION
REPRESSOR VAL1
(Arabidopsis
thaliana) 		5 / 9 PRO C 313
ALA C 319
GLU C 296
PHE C 321
LEU C 359
 None
 1.08A 4la0B-5yzzC:
undetectable		 4la0B-5yzzC:
8.16