SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A  73
LEU A 191
VAL A 108
ALA A  42
PRO A 120
 None
 1.10A 1dfoA-5z06A:
undetectable		 1dfoA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A  73
LEU A 191
VAL A 108
ALA A  42
PRO A 120
 None
 1.10A 1dfoB-5z06A:
undetectable		 1dfoB-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A  73
LEU A 191
VAL A 108
ALA A  42
PRO A 120
 None
 1.09A 1dfoC-5z06A:
undetectable		 1dfoC-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A  73
LEU A 191
VAL A 108
ALA A  42
PRO A 120
 None
 1.09A 1dfoD-5z06A:
undetectable		 1dfoD-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A  73
LEU A 191
VAL A 108
ALA A  42
PRO A 120
 None
 1.12A 1eqbA-5z06A:
undetectable		 1eqbA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A  73
LEU A 191
VAL A 108
ALA A  42
PRO A 120
 None
 1.12A 1eqbB-5z06A:
undetectable		 1eqbB-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A  73
LEU A 191
VAL A 108
ALA A  42
PRO A 120
 None
 1.12A 1eqbC-5z06A:
undetectable		 1eqbC-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A  73
LEU A 191
VAL A 108
ALA A  42
PRO A 120
 None
 1.12A 1eqbD-5z06A:
undetectable		 1eqbD-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A 648
LEU A 634
GLY A 664
ASN A 312
ALA A 311
 None
 1.12A 2bm9C-5z06A:
undetectable		 2bm9C-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 7 ASP A 379
ASN A 405
GLN A 469
TRP A 465
 None
 1.02A 2cmlA-5z06A:
undetectable		 2cmlA-5z06A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 LEU A 683
ALA A 327
HIS A 387
ASP A 408
 GOL  A 807 (-4.3A)
None
GOL  A 807 ( 4.6A)
None
 1.26A 2dpzA-5z06A:
undetectable		 2dpzA-5z06A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 TYR A 651
PHE A 665
LEU A 659
VAL A 688
ALA A 607
 None
 1.26A 2g72A-5z06A:
undetectable		 2g72A-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 7 GLN A 249
TYR A 248
TYR A 261
ILE A 224
 None
 1.23A 2ph9A-5z06A:
undetectable
2ph9B-5z06A:
undetectable		 2ph9A-5z06A:
21.63
2ph9B-5z06A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 7 TYR A 573
TRP A 480
TYR A 504
TYR A 570
 None
 1.32A 2ph9A-5z06A:
undetectable
2ph9B-5z06A:
undetectable		 2ph9A-5z06A:
21.63
2ph9B-5z06A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 GLY A 353
GLY A 346
PHE A 368
PHE A 426
 None
 0.69A 2qx6A-5z06A:
undetectable
2qx6B-5z06A:
undetectable		 2qx6A-5z06A:
16.67
2qx6B-5z06A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 GLN A 510
THR A 571
TRP A 480
 None
 1.02A 2rctA-5z06A:
undetectable		 2rctA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 10 ILE A 350
LEU A 375
ILE A 347
SER A 439
ILE A 440
 None
 1.20A 2w9sC-5z06A:
undetectable		 2w9sC-5z06A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 11 SER A 343
TYR A 315
ALA A 320
GLY A 325
SER A 324
 None
 1.28A 2xf3A-5z06A:
undetectable		 2xf3A-5z06A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 11 SER A 343
TYR A 315
ALA A 320
GLY A 325
SER A 324
 None
 1.28A 2xf3B-5z06A:
undetectable		 2xf3B-5z06A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A600_1
(ORF12)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 10 SER A 343
TYR A 315
ALA A 320
GLY A 325
SER A 324
 None
 1.32A 2xfsA-5z06A:
undetectable		 2xfsA-5z06A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 VAL A 410
ASN A 481
TRP A 480
 None
GOL  A 805 (-3.7A)
None
 0.69A 2y00B-5z06A:
undetectable		 2y00B-5z06A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 10 PHE A 345
GLY A 346
VAL A 351
ALA A 352
THR A 421
 None
 1.23A 3a3yA-5z06A:
undetectable		 3a3yA-5z06A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 MET A 348
PHE A 345
ALA A 342
GLY A 325
LEU A 375
 None
 1.21A 3aodC-5z06A:
undetectable		 3aodC-5z06A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 TYR A 517
GLY A 506
SER A 509
LEU A 461
HIS A 475
 GOL  A 805 (-4.6A)
None
None
None
GOL  A 805 (-4.6A)
 1.32A 3ou7C-5z06A:
undetectable		 3ou7C-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 5 LEU A 265
GLY A 266
PHE A 243
ARG A 241
 None
 0.96A 3smtA-5z06A:
undetectable		 3smtA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 10 ALA A 116
ARG A 138
LEU A 137
ASN A 136
ILE A 189
 None
 1.17A 3wdmB-5z06A:
undetectable		 3wdmB-5z06A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 10 ALA A 116
ARG A 138
LEU A 137
ASN A 136
ILE A 189
 None
 1.07A 3wdmD-5z06A:
undetectable		 3wdmD-5z06A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 8 TYR A 530
THR A 483
TYR A 573
TRP A 480
 None
 1.20A 3wipB-5z06A:
undetectable
3wipC-5z06A:
undetectable		 3wipB-5z06A:
undetectable
3wipC-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 8 TYR A 530
THR A 483
TYR A 573
TRP A 480
 None
 1.20A 3wipC-5z06A:
undetectable
3wipD-5z06A:
undetectable		 3wipC-5z06A:
undetectable
3wipD-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 5 LEU A 415
GLY A 418
ILE A 350
VAL A 351
 None
 0.89A 3wriB-5z06A:
undetectable		 3wriB-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 5 LEU A 415
GLY A 418
ILE A 350
VAL A 351
 None
 0.79A 3wrkA-5z06A:
1.8		 3wrkA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 GLU A 482
PHE A 553
TYR A 517
VAL A 524
 GOL  A 805 ( 2.6A)
GOL  A 805 (-4.4A)
GOL  A 805 (-4.6A)
None
 1.13A 4a97I-5z06A:
2.2		 4a97I-5z06A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 TYR A 315
GLN A 685
GLU A  29
LEU A 679
 None
 1.30A 4ax8A-5z06A:
undetectable		 4ax8A-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A 415
SER A 413
VAL A 447
GLY A 383
ALA A 384
 None
 1.12A 4coxC-5z06A:
undetectable		 4coxC-5z06A:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ARG A 623
TRP A 521
GLY A 522
 GOL  A 802 (-4.5A)
GOL  A 805 (-3.7A)
None
 0.67A 4e7cA-5z06A:
undetectable		 4e7cA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ARG A 518
TYR A 556
ASN A 577
 None
 0.92A 4ffwB-5z06A:
undetectable		 4ffwB-5z06A:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 GLY A 333
ASN A 330
TYR A 315
GLY A 319
 None
 0.90A 4fjpA-5z06A:
undetectable		 4fjpA-5z06A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A206_1
(UNCHARACTERIZED
PROTEIN)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 10 PHE A 553
PRO A 550
GLY A 604
ASN A 584
PHE A 552
 GOL  A 805 (-4.4A)
None
None
None
None
 1.34A 4kouA-5z06A:
undetectable		 4kouA-5z06A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 4 ASN A 591
GLY A 594
ASP A 667
ASP A 624
 None
 1.28A 4n49A-5z06A:
undetectable		 4n49A-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 8 LEU A  73
THR A  74
VAL A  76
SER A  77
 None
 1.06A 4qknA-5z06A:
2.9		 4qknA-5z06A:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ASP A 223
HIS A 221
LYS A 216
 None
 0.99A 4qzuD-5z06A:
undetectable		 4qzuD-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_0
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 PRO A 120
ILE A  87
GLU A 112
THR A  74
TYR A  75
 None
 1.37A 4rfqA-5z06A:
0.0		 4rfqA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 7 ARG A 586
ILE A 589
GLN A 585
ILE A 583
 None
 0.79A 4w5oA-5z06A:
undetectable		 4w5oA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 ARG A 586
ILE A 589
GLN A 585
ILE A 583
 None
 0.87A 4w5qA-5z06A:
undetectable		 4w5qA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 ARG A 586
ILE A 589
GLN A 585
ILE A 583
 None
 0.95A 4w5tA-5z06A:
undetectable		 4w5tA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 TYR A 281
ARG A 255
LYS A 235
 None
 1.29A 4wq5B-5z06A:
undetectable		 4wq5B-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 ARG A 586
ILE A 589
GLN A 585
ILE A 583
 None
 0.75A 4z4cA-5z06A:
undetectable		 4z4cA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 ARG A 586
ILE A 589
GLN A 585
ILE A 583
 None
 0.79A 4z4dA-5z06A:
undetectable		 4z4dA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 7 ARG A 586
ILE A 589
GLN A 585
ILE A 583
 None
 0.81A 4z4eA-5z06A:
undetectable		 4z4eA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 7 ARG A 586
ILE A 589
GLN A 585
ILE A 583
 None
 0.81A 4z4gA-5z06A:
undetectable		 4z4gA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 LEU A 634
ALA A 635
PHE A 637
TYR A 556
LEU A 559
 None
 1.10A 5k9dA-5z06A:
undetectable		 5k9dA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 8 TYR A 651
THR A 627
CYH A 588
LEU A 605
 None
 1.15A 5kxiA-5z06A:
2.4
5kxiB-5z06A:
2.2		 5kxiA-5z06A:
14.04
5kxiB-5z06A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 8 TYR A 651
THR A 627
CYH A 588
LEU A 605
 None
 1.25A 5kxiA-5z06A:
2.4
5kxiB-5z06A:
2.2		 5kxiA-5z06A:
14.04
5kxiB-5z06A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 8 TYR A 651
THR A 627
CYH A 588
LEU A 605
 None
 1.17A 5kxiD-5z06A:
2.5
5kxiE-5z06A:
2.5		 5kxiD-5z06A:
14.04
5kxiE-5z06A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 8 TYR A 651
THR A 627
CYH A 588
LEU A 605
 None
 1.32A 5kxiD-5z06A:
2.5
5kxiE-5z06A:
2.5		 5kxiD-5z06A:
14.04
5kxiE-5z06A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 TYR A 452
SER A 450
TRP A 471
 None
 0.96A 5n8jB-5z06A:
undetectable		 5n8jB-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 TYR A 452
SER A 450
TRP A 471
 None
 0.94A 5n8jA-5z06A:
undetectable		 5n8jA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 TYR A 452
SER A 450
TRP A 471
 None
 0.97A 5n8jD-5z06A:
undetectable		 5n8jD-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 4 PHE A 680
LEU A 648
LEU A 659
VAL A 688
 None
 0.96A 5xxiA-5z06A:
undetectable		 5xxiA-5z06A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 11 MET A 620
TYR A 536
ASN A 532
VAL A 524
GLY A 522
 None
 1.26A 5yjsA-5z06A:
2.0		 5yjsA-5z06A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_B_SALB601_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 9 MET A 620
TYR A 536
ASN A 532
VAL A 524
GLY A 522
 None
 1.27A 5yjsB-5z06A:
0.0		 5yjsB-5z06A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 GLY A 682
GLY A 346
ASN A 684
LEU A 679
ASP A 609
 None
 1.22A 5yn6A-5z06A:
undetectable		 5yn6A-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 GLY A 682
GLY A 346
ASN A 684
LEU A 679
ASP A 609
 None
 1.22A 5yniA-5z06A:
undetectable		 5yniA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 GLY A 682
GLY A 346
ASN A 684
LEU A 679
ASP A 609
 None
 1.22A 5ynmA-5z06A:
undetectable		 5ynmA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 GLY A 713
GLY A 493
PRO A 494
GLY A 497
 None
 0.72A 6ag0C-5z06A:
undetectable		 6ag0C-5z06A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		5 / 12 ILE A 122
LEU A 172
LEU A 137
PHE A 159
LEU A 141
 None
 1.22A 6b54A-5z06A:
undetectable		 6b54A-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		4 / 6 ARG A 586
ILE A 589
GLN A 585
ILE A 583
 None
 0.92A 6cbdA-5z06A:
undetectable		 6cbdA-5z06A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 LEU A 369
GLN A 366
LYS A 438
 None
 0.99A 6exiB-5z06A:
undetectable		 6exiB-5z06A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5z06 BDI_3064 PROTEIN
(Parabacteroides
distasonis) 		3 / 3 LEU A 369
GLN A 366
LYS A 438
 None
 0.96A 6exiA-5z06A:
undetectable		 6exiA-5z06A:
21.25